tetramethyl bicyclo[2.2.2]oct-7-ene-2,3,5,6-tetracarboxylate | 56745-93-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: tetramethyl bicyclo[2.2.2]oct-7-ene-2,3,5,6-tetracarboxylate
• 英文别名: 5.6.7.8-exo-Tetracarbomethoxy-bicyclo<2.2.2>-oct-2-en；tetramethyl (2R,3S,5R,6S)-bicyclo[2.2.2]oct-7-ene-2,3,5,6-tetracarboxylate
• CAS: 56745-93-8；56782-33-3；56782-35-5；56782-36-6；72598-54-0；81203-29-4；108211-26-3；108211-27-4
• 化学式: C₁₆H₂₀O₈
• 分子量: 340.33
• InChiKey: CAOGMEMPDFAZPR-TZGWRFBESA-N

物化性质

• 熔点：
  149-149.5 °C(Solvent: Methanol)
• 沸点：
  418.8±45.0 °C(Predicted)
• 密度：
  1.276±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  24
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  105
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  tetramethyl bicyclo[2.2.2]oct-7-ene-2,3,5,6-tetracarboxylate 在 HOF* CH₃CN 作用下， 反应 0.02h， 以80%的产率得到(6R,7S,8R,9S)-3-Oxa-tricyclo[3.2.2.0^2,4]nonane-6,7,8,9-tetracarboxylic acid tetramethyl ester
  参考文献：
  名称：

  An easy way for constructing hard-to-make epoxides employing HOF·CH3CN

  摘要：

  HOF-CH2CN, a very efficient oxygen transfer agent, was reacted with various types of difficult-to-epoxidize olefine. All products were obtained in a single-step, fast and high yield reaction. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2004.03.030

文献信息

• IORDACHE F.; GHIRALEU F.; STANESCU L.; BADEA F.; AVRAM M., REV. ROUM. CHIM., 31,(1986) N 3, 261-267
  作者：IORDACHE F.、 GHIRALEU F.、 STANESCU L.、 BADEA F.、 AVRAM M.

  DOI：——

  日期：——
• An easy way for constructing hard-to-make epoxides employing HOF·CH3CN
  作者：Elizabeth Golan、Aviv Hagooly、Shlomo Rozen

  DOI：10.1016/j.tetlet.2004.03.030

  日期：2004.4

  HOF-CH2CN, a very efficient oxygen transfer agent, was reacted with various types of difficult-to-epoxidize olefine. All products were obtained in a single-step, fast and high yield reaction. (C) 2004 Elsevier Ltd. All rights reserved.