1-Ethoxy-2,4(1H,3H)-pyrimidinedione | 58909-44-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 1-Ethoxy-2,4(1H,3H)-pyrimidinedione
• 英文别名: 1-ethoxypyrimidine-2,4-dione
• CAS: 58909-44-7
• 化学式: C₆H₈N₂O₃
• 分子量: 156.14
• InChiKey: LUSOOAZYADXWHN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.4
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  58.6
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• NUCLEIC ACIDS, PROTEINS, AND ANTIBODIES
  申请人：Human Genome Sciences, Inc.

  公开号：EP1254219A2

  公开（公告）日：2002-11-06
• US4091211A
  申请人：——

  公开号：US4091211A

  公开（公告）日：1978-05-23
• US4348518A
  申请人：——

  公开号：US4348518A

  公开（公告）日：1982-09-07
• [EN] NUCLEIC ACIDS, PROTEINS, AND ANTIBODIES<br/>[FR] ACIDES NUCLEIQUES, PROTEINES ET ANTICORPS
  申请人：HUMAN GENOME SCIENCES INC

  公开号：WO2001055300A2

  公开（公告）日：2001-08-02

  The present invention relates to novel lung cancer related polynucleotides and the polypeptides encoded by these polynucleotides herein collectively known as 'lung cancer antigens', and the use of such lung cancer antigens for detecting disorders of the lung, particularly the presence of lung cancer and lung cancer metastases. More specifically, isolated lung cancer associated nucleic acid molecules are provided encoding novel lung cancer associated polypeptides. Novel lung cancer polypeptides and antibodies that bind to these polypeptides are provided. Also provided are vectors, host cells, and recombinant and synthetic methods for producing human lung cancer associated polynucleotides and/or polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing, treating, preventing and/or prognosing disorders related to the lung, including lung cancer, and therapeutic methods for treating such disorders. The invention further relates to screening methods for identifying agonists and antagonists of polynucleotides and polypeptides of the invention. The present invention further relates to methods and/or compositions for inhibiting the production and function of the polypeptides of the present invention.