(R)-3-(allylthio)-2-((R)-3-(allylthio)-2-aminopropanamido)propanoic acid | 1609455-99-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (R)-3-(allylthio)-2-((R)-3-(allylthio)-2-aminopropanamido)propanoic acid
• 英文别名: (2R)-2-[[(2R)-2-amino-3-prop-2-enylsulfanylpropanoyl]amino]-3-prop-2-enylsulfanylpropanoic acid
• CAS: 1609455-99-3
• 化学式: C₁₂H₂₀N₂O₃S₂
• 分子量: 304.434
• InChiKey: LHULZANLATXLRF-UWVGGRQHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.4
• 重原子数：
  19
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  143
• 氢给体数：
  3
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  (R)-3-(allylthio)-2-((R)-3-(allylthio)-2-aminopropanamido)propanoic acid 在 盐酸 作用下， 以 水 为溶剂， 反应 18.0h， 以2 mg的产率得到S-烯丙基-L-半胱氨酸
  参考文献：
  名称：

  A new dipeptide isolated from the bulb of garlic

  摘要：

  (R)-3-(allylthio)-2-((R)-3-(allylthio)-2-aminopropanamido)propanoic acid was isolated from the bulb of garlic, together with four known amino acids. Its structure was elucidated on the basis of 2D NMR and MS techniques. To the best of our knowledge, (R)-3-(allylthio)-2-((R)-3-(allylthio)-2-aminopropanamido)propanoic acid, which showed antibacterial activity against the Staphylococcus aureus antibiotic resistant strain, was the first example of dipeptide from garlic.

  DOI：

  10.1080/10286020.2013.868886

文献信息

• A new dipeptide isolated from the bulb of garlic
  作者：Mei-Yun Zhou、Zhao-Jun Wu、Wen-Qing Li、Xing-Peng Hu、Rian Yan、Shi-Yi Ou、Hua Zhou

  DOI：10.1080/10286020.2013.868886

  日期：2014.3.4

  (R)-3-(allylthio)-2-((R)-3-(allylthio)-2-aminopropanamido)propanoic acid was isolated from the bulb of garlic, together with four known amino acids. Its structure was elucidated on the basis of 2D NMR and MS techniques. To the best of our knowledge, (R)-3-(allylthio)-2-((R)-3-(allylthio)-2-aminopropanamido)propanoic acid, which showed antibacterial activity against the Staphylococcus aureus antibiotic resistant strain, was the first example of dipeptide from garlic.