diphenyl-2-pyridylmethyl methacrylate | 88718-71-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: diphenyl-2-pyridylmethyl methacrylate
• 英文别名: Diphenyl(pyridin-2-yl)methyl 2-methylprop-2-enoate；[diphenyl(pyridin-2-yl)methyl] 2-methylprop-2-enoate
• CAS: 88718-71-2
• 化学式: C₂₂H₁₉NO₂
• 分子量: 329.398
• InChiKey: YUWSXYQUCFBRQW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  25
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  39.2
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  diphenyl-2-pyridylmethyl methacrylate 在 间氯过氧苯甲酸 作用下， 以 二氯甲烷 为溶剂， 反应 20.0h， 生成
  参考文献：
  名称：

  Pyridyl N-Oxide Substituted Helically Chiral Poly(methacrylate)s in Asymmetric Organocatalysis

  摘要：

  Four pyridyl substituted helically chiral poly(methacrylate)s poly-1-poly-4 were oxidized with m-CPBA, yielding four pyridyl N-oxide substituted polymers poly-5-poly-8. Poly[(3-pyridyl N-oxide)-dibenzosuberyl methacrylate] poly(3PyDBSMA-NO) poly-5 was found to be quantitatively oxidized and showed a stable helical conformation. It was an active organocatalyst in the asymmetric allylation of benzaldehyde with allyltrichlorosilane.

  DOI：

  10.1021/ma0503357

文献信息

• Polymerizable, optically active polymer and process for preparing polymerizable polymer
  申请人：DAICEL CHEMICAL INDUSTRIES, LTD.

  公开号：EP0095086A1

  公开（公告）日：1983-11-30

  A polymerizable polymer is obtained by the anionic polymerization and termination by use of a vinyl monomer. It produces a graft copolymer by co-polymerization with another monomer. The process produces a new, polymerizable, optically active polymer and a graft copolymer thereof.

  一种可聚合聚合物是通过阴离子聚合并使用乙烯基单体终止而得到的。它通过与另一种单体共聚产生接枝共聚物。该工艺可生产出一种新的、可聚合的光学活性聚合物及其接枝共聚物。
• Responsive microgel and methods related thereto
  申请人：——

  公开号：US20030152623A1

  公开（公告）日：2003-08-14

  A responsive microgel is provided which responds volumetrically and reversibly to a change in one or more aqueous conditions selected from the group consisting of (temperature, pH, and ionic conditions) comprised of an ionizable network of covalently cross-linked homopolymeric ionizable monomers wherein the ionizable network is covalently attached to an amphiphilic copolymer to form a plurality of ‘dangling chains’ and wherein the ‘dangling chains’ of amphiphilic copolymer form immobile micelle-like aggregates in aqueous solution. A responsive microgel is further provided that comprises at least one therapeutic entity and delivers a substantially linear and sustained release of the therapeutic entity under physiological conditions.

  本发明提供了一种响应型微凝胶，该微凝胶可对选自由温度、pH 值和离子条件组成的组中的一种或多种水性条件的变化作出体积上和可逆的响应、和离子条件）组成的共价交联均聚可离子化单体的可离子化网络，其中可离子化网络与两性共聚物共价连接，形成多条 "悬链"，两性共聚物的 "悬链 "在水溶液中形成不动的胶束状聚集体。还提供了一种响应性微凝胶，它包含至少一种治疗实体，并能在生理条件下提供治疗实体的线性和持续释放。
• RESPONSIVE MICROGEL AND METHODS RELATED THERETO
  申请人：SUPRATEK PHARMA, INC.

  公开号：EP1478403A1

  公开（公告）日：2004-11-24
• JP1066207A
  申请人：——

  公开号：JP1066207A

  公开（公告）日：1989-03-13
• JPS6069111A
  申请人：——

  公开号：JPS6069111A

  公开（公告）日：1985-04-19