P-ETHOXYBENZYLIDENE P-HEPTYLANILINE | 39777-17-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: P-ETHOXYBENZYLIDENE P-HEPTYLANILINE
• 英文别名: [1-(4-Ethoxy-phenyl)-meth-(E)-ylidene]-(4-heptyl-phenyl)-amine
• CAS: 39777-17-8
• 化学式: C₂₂H₂₉NO
• 分子量: 323.478
• InChiKey: FPODOKAXFSGBSS-PTGBLXJZSA-N

物化性质

• 沸点：
  455.9±38.0 °C(Predicted)
• 密度：
  0.95±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.35
• 重原子数：
  24.0
• 可旋转键数：
  10.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.41
• 拓扑面积：
  21.59
• 氢给体数：
  0.0
• 氢受体数：
  2.0

文献信息

• METHODS AND COMPOSITIONS OF TRAIL-DEATH RECEPTOR AGONISTS/ACTIVATORS
  申请人：Srivastava Rakesh K.

  公开号：US20080214547A1

  公开（公告）日：2008-09-04

  This invention describes a series of methods and compositions for prevention and treatment of diseases such as cancer. One aspect of the invention describes small molecule-based drugs that can be used to bind to death receptors TRAIL-R1/DR4 and/or TRAIL-R2/DR5 and induce apoptosis in cancer cells, while sparing normal cells. The invention also describes TRAIL Death Receptor Agonists/Activators (DRAs) and their uses, such as the induction of apoptosis through caspase-8 and caspase-3 activation. The present invention also describes the methods of treating cancers, such as breast, prostate, colon, pancreatic, ovarian, lung, and brain cancers, leukemia, lymphoma, multiple myeloma, and mesothelioma, using DRAs either as single-agent treatments, or in combination with other therapies.
• SMALL SCALE FUNCTIONAL MATERIALS
  申请人：Shaffer, II Edward O.

  公开号：US20100294989A1

  公开（公告）日：2010-11-25

  The disclosure provides for a small scale functional material, where the small scale functional material is imbibed with a material having a functionality response to an externally applied field.
• PHASE COMPENSATION FILM
  申请人：Storer Joey W.

  公开号：US20100302487A1

  公开（公告）日：2010-12-02

  The disclosure provides for a phase compensation film that includes nano-particles of a cross-linked polymer with a largest dimension of a quarter of a wavelength of visible light or less, and a liquid crystal substance imbibed substantially throughout the cross-linked polymer of the nano-particles to provide a phase compensation value for a pixel of a liquid crystal display.
• US3977768A
  申请人：——

  公开号：US3977768A

  公开（公告）日：1976-08-31
• US3989639A
  申请人：——

  公开号：US3989639A

  公开（公告）日：1976-11-02