N-Aethyl-phenoxy-acetamid | 57186-78-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: N-Aethyl-phenoxy-acetamid
• 英文别名: N-Ethyl-phenoxyacetamid；N-ethyl-2-phenoxyacetamide
• CAS: 57186-78-4
• 化学式: C₁₀H₁₃NO₂
• mdl: MFCD02861622
• 分子量: 179.219
• InChiKey: NELYNPDQYTTZHB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.07
• 重原子数：
  13.0
• 可旋转键数：
  4.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  38.33
• 氢给体数：
  1.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  N-Aethyl-phenoxy-acetamid 在 lithium aluminium tetrahydride 、 乙醚 作用下， 生成 N-乙基-2-苯氧基乙胺
  参考文献：
  名称：

  Hypoglycemic Agents. II.^1—3 Arylbiguanides

  摘要：

  DOI：

  10.1021/ja01523a059

文献信息

• Compound Combinations for Attenuation of Bacterial Virulence
  申请人：WISCONSIN ALUMNI RESEARCH FOUNDATION

  公开号：US20170231962A1

  公开（公告）日：2017-08-17

  Methods for modulating quorum sensing in certain Gram-negative bacteria having multiple QS systems including Las, Rhl, and Pqs with associated receptors (LasR, RhlR and PqsR) which are modulated by small molecule modulators, particularly non-native modulators. Certain combinations of modulators of Las, Rhl and Pqs exhibit improved inhibition of virulence in comparison to the respective individual modulators. In particular, certain combinations of modulators exhibit improved inhibition in nutritionally depleted environments. More specifically, certain combinations of modulators exhibit improved inhibition in environments depleted in phosphate and/or environments depleted in iron. Nutrient depleted environments can mimic environments associated with bacterial infection in humans and non-human animals. The methods are useful in particular for modulating QS in Pseudomonas and Buckholderia.

  在某些具有多个QS系统的革兰氏阴性细菌中，包括具有相关受体（LasR、RhlR和PqsR）的Las、Rhl和Pqs的调控方法，这些受体受小分子调节剂（尤其是非天然调节剂）的调节。Las、Rhl和Pqs的某些调节剂组合相比于各自的单个调节剂表现出对毒力的改善抑制。特别是，某些调节剂组合在营养匮乏环境中表现出改善的抑制作用。更具体地说，某些调节剂组合在缺乏磷酸盐和/或缺乏铁的环境中表现出改善的抑制作用。营养匮乏环境可以模拟与人类和非人类动物细菌感染相关的环境。这些方法特别适用于调节假单胞菌和布氏杆菌中的QS。
• VISCOSITY IMPROVER GRAFTED WITH UNSATURATED ACYLATING AGENT AND AN ARYLOXYALYLKENE MONOAMINE
  申请人：McDougall Patrick J.

  公开号：US20140024567A1

  公开（公告）日：2014-01-23

  Disclosed is an oil-soluble lubricating oil additive composition, suitable for use as a dispersant viscosity index improver in lubricating oils; prepared by the process which comprises reacting a hydrocarbon polymer having a number average molecular weight (M n ) between about 7,000 and about 500,000 wherein the polymer backbone has been functionalized with an ethylenically unsaturated acylating agent and an aryloxy-alkylene amine.

  本发明公开了一种油溶性润滑油添加剂组合物，适用于用作润滑油中的分散剂粘度指数改进剂；所述组合物是通过以下过程制备的：反应具有约7,000至约500,000的数均分子量（Mn）的烃基聚合物，其中聚合物骨架已经被乙烯基不饱和酰化剂和芳基氧基-烷基胺官能化。
• Synergistic lubricating oil composition containing a mixture of olefin copolymer dispersant-type viscosity improver and amine compound
  申请人：Chevron Oronite Company LLC

  公开号：US10414999B2

  公开（公告）日：2019-09-17

  Disclosed is an internal combustion engine lubricating oil composition which comprises (a) a major amount of an oil of lubricating viscosity; (b) a dispersant-type olefin copolymer VI improver; and (c) a secondary hydrocarbylamine compound, a tertiary hydrocarbylamine compound, or combinations thereof. A method for reducing cam wear using same is also disclosed.

  本发明公开了一种内燃机润滑油组合物，它包含：(a) 一种润滑粘度油的主要成分；(b) 一种分散剂型烯烃共聚物 VI 改良剂；以及 (c) 一种仲烃基胺化合物、一种叔烃基胺化合物或它们的组合。此外，还公开了一种使用该制剂减少凸轮磨损的方法。
• BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR
  申请人：R-Tech Ueno, Ltd.

  公开号：EP2300430A1

  公开（公告）日：2011-03-30
• SYNERGISTIC LUBRICATING OIL COMPOSITION CONTAINING A MIXTURE OF OLEFIN COPOLYMER DISPERSANT-TYPE VISCOSITY IMPROVER AND AMINE COMPOUND
  申请人：Chevron Oronite Company LLC

  公开号：EP3405554A1

  公开（公告）日：2018-11-28