5-methyl-1,3-dioxolane-2,4-dione | 17578-13-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氧戊环
• 英文名称: 5-methyl-1,3-dioxolane-2,4-dione
• 英文别名: lactic acid O-carboxyanhydride；5-methyl-[1,3]dioxolane-2,4-dione；5-Methyl-[1,3]dioxolan-2,4-dion；O-carboxy-α-hydroxypropionic anhydride；O-carboxy anhydride of (D,L) lactic acid
• CAS: 17578-13-1
• 化学式: C₄H₄O₄
• 分子量: 116.073
• InChiKey: JLXQJNCZXSYXAK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  5-methyl-1,3-dioxolane-2,4-dione 、 methyloxirane 在 [N,N'-bis(3,5-di-tertbutylsalicylidene)-1,2-cyclohexanediimine]CoCl 、 双(三苯基正膦基)氯化铵 作用下， 反应 1.0h， 以100%的产率得到碳酸丙烯酯
  参考文献：
  名称：

  One-pot atom-efficient synthesis of bio-renewable polyesters and cyclic carbonates through tandem catalysis

  摘要：

  通过使用金属salen络合物作为催化剂，首次成功地实现了高收率合成明确定义的生物可再生聚酯和环状碳酸酯的一锅法合成。

  DOI：

  10.1039/c5cc01329a
• 作为产物：
  描述：

  乳酸 在 1,4-二氧六环 、 光气 作用下， 生成 5-methyl-1,3-dioxolane-2,4-dione
  参考文献：
  名称：

  302.羟基和巯基酸的脱水羧基衍生物

  摘要：

  DOI：

  10.1039/jr9510001357

文献信息

• Alternating Sequence Controlled Copolymer Synthesis of α-Hydroxy Acids via Syndioselective Ring-Opening Polymerization of <i>O</i>-Carboxyanhydrides Using Zirconium/Hafnium Alkoxide Initiators
  作者：Yangyang Sun、Zhaowei Jia、Changjuan Chen、Yong Cong、Xiaoyang Mao、Jincai Wu

  DOI：10.1021/jacs.7b04712

  日期：2017.8.9

  challenges until now for lack of suitable catalysts/initiators. In this work, a highly syndioselective ROP of OCAs system as the first stereoselective example in this area is reported using zirconium/hafnium alkoxides as initiators with the highest Pr value up to 0.95. Furthermore, these initiators were successfully applied in the precisely alternating sequence controlled copolymerization of PheOCA and

  O-羧酸酐（OCA）的开环聚合（ROP）由于易于修饰OCA的侧基，可以得到具有不同官能团的多种聚（α-羟基酸）（PAHAs），这可以扩展PAHAs的应用广泛。由于缺乏合适的催化剂/引发剂，O-羧酸酐的立体选择性聚合和OCA的进一步顺序控制交替共聚仍然是一个巨大的挑战。在这项工作中，报道了使用锆/铪醇盐作为引发剂的 OCA 系统的高度间选择性 ROP 作为该领域的第一个立体选择性例子，最高 Pr 值高达 0.95。此外，这些引发剂已成功应用于 PheOCA 和 Tyr(Bn)OCA 的精确交替顺序控制共聚，
• Flavour Improving Substances
  申请人：Haiber Stephan

  公开号：US20100087524A1

  公开（公告）日：2010-04-08

  One aspect of the invention relates to a product selected from the group consisting of foodstuffs, beverages, oral care products, tobacco products and flavourings, said product containing at least 0.01 mg/kg of one or more flavour improving substances selected from the group of substituted phenol esters represented by the following the formula, salts of these compounds and combinations thereof: Formula (I). The invention also relates to novel substituted phenol esters represented by the above formula. Examples of the present flavour improving substances include lactoyl vanillin, lactoyl ethylvanillin, lactoyl isovanillin, lactoyl p-hydroxybenzaldehyde, lactoyl p-hydroxy-m-methoxycinnamaldehyde, lactoyl p-hydroxy-m-methoxycinnamic acid, lactoyl vanillic acid, lactoyl homovanillic acid, lactoyl-m-hydroxybenzoic acid, lactoyl isovanillic acid, lactoyl-p-hydroxy-m-methoxyacetophenone, oleyl vanillin, decanoyl vanillin, divanillyl succinate, lactoyl-o-hydroxy-m-methoxybenzaldehyde, lactoyl eugenol, gluconyl vanillin, and edible salts and esters thereof.

  本发明的一个方面涉及从食品、饮料、口腔护理产品、烟草产品和调味品组成的群体中选择的产品，该产品含有至少0.01毫克/千克的一种或多种从以下公式所代表的取代酚酯群体中选择的提味物质：Formula (I)。该发明还涉及由上述公式代表的新型取代酚酯。当前提味物质的例子包括乳酰香草醛、乳酰乙基香草醛、乳酰异香草醛、乳酰对羟基苯甲醛、乳酰对羟基间甲氧基肉桂醛、乳酰对羟基间甲氧基肉桂酸、乳酰香草酸、乳酰异香草酸、乳酰-m-羟基苯甲酸、乳酰异香草酸、乳酰对羟基间甲氧基苯乙酮、油酰香草醛、癸酰香草醛、二香草酸丁酯、乳酰-o-羟基间甲氧基苯甲醛、乳酰丁香酚、葡萄糖香草醛，以及其可食用的盐和酯。
• Tailoring Electrolyte Additives with Synergistic Functional Moieties for Silicon Negative Electrode-Based Lithium Ion Batteries: A Case Study on Lactic Acid <i>O</i>-Carboxyanhydride
  作者：Roman Nölle、Jan-Patrick Schmiegel、Martin Winter、Tobias Placke

  DOI：10.1021/acs.chemmater.9b03173

  日期：2020.1.14

  material for lithium ion batteries (LIBs) with increased energy density. However, the huge volume changes during (de-)lithiation of the Si, accompanied with the breakdown of the initially formed solid electrolyte interphase (SEI), result in the gradual consumption of active lithium and electrolyte and, hence, a poor cycling performance of LIBs with Si-based N. The addition of various electrolyte additives

  硅（Si）引起了极大的关注，被用作能量密度提高的锂离子电池（LIB）的负极（N）材料。然而，在硅的（去）锂化期间，巨大的体积变化，伴随着最初形成的固体电解质中间相（SEI）的分解，导致活性锂和电解质逐渐消耗，因此循环性能差。具有硅基N的LIB。事实证明，添加各种电解质添加剂可通过形成更有效/更具柔韧性的方法来减少活性锂的消耗，从而更好地保护Si上的SEI。在这项研究中，我们合成了新的电解质添加剂乳酸O-羧基酸酐（lacOCA），旨在在其结构中结合两个不同的部分，两者均显示出作为有效的SEI添加剂的功能。在放电容量保持率和库仑效率方面，向基线电解质中添加少量2 wt％的lacOCA可以显着提高NMC-111 || Si全电池的电化学性能。lacOCA的性能也优于同类的丙交酯和二碳酸二乙酯，它们被选择单独代表掺入lacOCA结构中的部分，从而证明了两个不同部分在一个分子中的协同作用。
• LC-MS Study To Reduce Ion Suppression and To Identify <i>N</i>-Lactoylguanosine 5‘-Monophosphate in Bonito:  A New Umami Molecule?
  作者：Eva de Rijke、Bart Ruisch、Jan Bakker、Jan Visser、Jeroen Leenen、Stephan Haiber、Adri de Klerk、Chris Winkel、Thorsten König

  DOI：10.1021/jf0704007

  日期：2007.8.1

  In this study a specific taste modulating flavor ingredient, N-lactoylguanosine 5'-monophosphate (N-lactoyl GMP), was determined in bonito (Japanese, Katsuobushi, dried fermented skipjack) and in powdered bonito using liquid chromatography-electrospray ionization (+) mass spectrometry-mass spectrometry (LC-ESI(+)-MS/MS) with a methanol/ammonium acetate or formate gradient. Furthermore, the influence of ion suppression due to sample matrix effect was investigated and was found to substantially influence the total MS response of N-lactoyl GMP; by adjusting the LC conditions the response could be approximately 5-fold-enhanced. The N-lactoyl GMP concentrations in different types of bonito products were between 0.2 and 2.4 mu g/g.
• Gulbins,K. et al., Angewandte Chemie, 1961, vol. 73, p. 434
  作者：Gulbins,K. et al.

  DOI：——

  日期：——