4-[2-(4-dimethylaminophenyl)phenyl]-N,N-dimethylaniline | 130951-79-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-[2-(4-dimethylaminophenyl)phenyl]-N,N-dimethylaniline
• 英文别名: 4-[2-[4-(dimethylamino)phenyl]phenyl]-N,N-dimethylaniline
• CAS: 130951-79-0
• 化学式: C₂₂H₂₄N₂
• 分子量: 316.446
• InChiKey: TWXMDDZUOWVTJI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.3
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  6.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  chlorozinc(1+),N,N-dimethylaniline 、 邻二氯苯 在 Ni(Cl){2-(Ph₂P)C₆H₄NCH(Ph)P(O)Ph₂} 作用下， 以 四氢呋喃 、 N-甲基吡咯烷酮 为溶剂， 反应 24.0h， 以86%的产率得到4-[2-(4-dimethylaminophenyl)phenyl]-N,N-dimethylaniline
  参考文献：
  名称：

  室温下镍催化的芳基氯化物与芳基锌的交叉偶联。

  摘要：

  P，N，O-螯合物镍络合物可有效催化芳基氯化物与芳基锌试剂在1：1 THF-NMP混合物中的交叉偶联反应。反应在室温下以低催化剂负载进行。

  DOI：

  10.1039/c0cc03064c

文献信息

• Selective Mechanochemical Monoarylation of Unbiased Dibromoarenes by <i>in Situ</i> Crystallization
  作者：Tamae Seo、Koji Kubota、Hajime Ito

  DOI：10.1021/jacs.0c01739

  日期：2020.6.3

  Palladium-catalyzed Suzuki-Miyaura cross-coupling reactions of liquid, unbiased dibromoarenes under mechanochemical conditions selectively afford the monoarylated products. The lower reactivity of the crystalline monoarylated products rela-tive to the liquid starting materials should be attributed predom-inantly to the low diffusion efficiency of the former in the re-action mixture, which results in

  在机械化学条件下，钯催化的液体无偏二溴芳烃的 Suzuki-Miyaura 交叉偶联反应选择性地提供单芳基化产物。结晶单芳基化产物相对于液体原料的较低反应性主要归因于前者在反应混合物中的低扩散效率，这导致选择性单芳基化。本研究揭示了一种新方法，该方法使用固体中的原位相变来设计通过传统的基于溶液的合成难以实现的选择性有机转化。
• An Extremely Active and General Catalyst for Suzuki Coupling Reaction of Unreactive Aryl Chlorides
  作者：Dong-Hwan Lee、Myung-Jong Jin

  DOI：10.1021/ol102677r

  日期：2011.1.21

  2a acted as a powerful catalyst which allows easy access to the Suzuki coupling reaction of less reactive aryl chlorides under mild conditions. A wide range of sterically hindered and deactivated aryl chlorides could be efficiently coupled at a low catalyst loading of 0.1 mol %. Furthermore, this catalytic system also proved to be highly effective in one-pot multiple couplings.

  β-二酮亚氨基膦Pd络合物2a用作强力催化剂，可在温和条件下轻松进入反应性较低的芳基氯化物的Suzuki偶联反应。可以在0.1 mol％的低催化剂负载量下有效地偶联各种空间受阻和失活的芳基氯化物。此外，该催化体系在一锅多联中也被证明是非常有效的。
• Cross-Coupling of ArX with ArMgBr Catalyzed by N-Heterocyclic Carbene-Based Nickel Complexes
  作者：Wang-Jun Guo、Zhong-Xia Wang

  DOI：10.1021/jo302425x

  日期：2013.2.1

  N-Heterocyclic carbene-based pincer nickel complexes were synthesized and characterized. These complexes efficiently catalyze cross-coupling of aryl Grignard reagents with aryl chlorides or fluorides under mild conditions.
• ORGANIC ELECTROLUMINESCENT DEVICE
  申请人：HODOGAYA CHEMICAL CO., LTD.

  公开号：US20170358754A1

  公开（公告）日：2017-12-14

  The organic EL device of the present invention has an anode, a first hole transport layer, a second hole transport layer, a luminous layer, an electron transport layer, and a cathode in the order of description. The second hole transport layer includes an arylamine derivative represented by the following general formula (1): and the electron transport layer includes a pyrimidine compound represented by the following general formula (2):
• ORGANIC ELECTROLUMINESCENCE DEVICE
  申请人：HODOGAYA CHEMICAL CO., LTD.

  公开号：US20180212153A1

  公开（公告）日：2018-07-26

  According to the present invention, there is provided an organic electroluminescent device which has an anode, a hole transport layer, a luminous layer, an electron transport layer, and a cathode arranged in order of description. The device is characterized in that: the hole transport layer includes a specific arylamine compound, and that the luminous layer includes a specific indenoindole derivative or a specific carbazole derivative. The organic EL device of the present invention has improved efficiency of hole transport from the hole transport layer to the luminous layer and also improved efficiency of electron transport from the electron transport layer to the luminous layer, in comparison to conventional organic EL devices.