2-(tetramethyleneimino)ethyl methacrylate | 88677-57-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: 2-(tetramethyleneimino)ethyl methacrylate
• 英文别名: 2-(1-pyrrolidinyl)ethyl methacrylate；2-Pyrrolidin-1-ylethyl 2-methylprop-2-enoate
• CAS: 88677-57-0
• 化学式: C₁₀H₁₇NO₂
• 分子量: 183.25
• InChiKey: DBNCSQNIKKWMEA-UHFFFAOYSA-N

物化性质

• 沸点：
  262.7±23.0 °C(Predicted)
• 密度：
  1.008±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  N-(2-羟乙基)-吡咯烷 、 甲基丙烯酰氯 在 三乙胺 、 对苯二酚 作用下， 以 四氢呋喃 为溶剂， 反应 2.0h， 以78%的产率得到2-(tetramethyleneimino)ethyl methacrylate
  参考文献：
  名称：

  靶向活细胞中特定内吞细胞器的可调、超灵敏 pH 响应纳米颗粒

  摘要：

  切换：可调节的、pH 响应性纳米颗粒可以在不同的内吞隔室中被选择性激活。在高 pH 值下，胶束形成（见左图）通过 Förster 共振能量转移淬灭荧光。胶束在低 pH 值下分解，导致荧光发射。这种非线性开/关纳米平台在诊断成像和药物输送应用中提供了许多令人兴奋的机会。

  DOI：

  10.1002/anie.201100884

文献信息

• Block ethylenic copolymers comprising a vinyllactam block, cosmetic or pharmaceutical compositions containing them and cosmetic use of these copolymers
  申请人：Mougin Nathalie

  公开号：US20060088487A1

  公开（公告）日：2006-04-27

  Disclosed herein are a linear block ethylenic copolymer comprising: at least one block A obtained from monomers comprising from 52% to 99% by weight of at least one ethylenic monomer comprising a lactam ring, of formula (I): and from 1% to 48% by weight of at least one ionic hydrophilic monomer; and at least one block B obtained from monomers not comprising an ethylenic monomer comprising a lactam ring of formula (I), or comprising a minor proportion thereof; a cosmetic or pharmaceutical composition, such as a hair composition, comprising the copolymer; a cosmetic process for making up or caring for keratin materials, comprising applying to the keratin materials the composition; and other uses of the copolymer.

  本文揭示了一种线性块状乙烯共聚物，包括：至少一种A块，其由包含至少一种含有内酰胺环的乙烯单体的重量为52%至99%的单体和含有至少一种离子亲水性单体的重量为1%至48%的单体得到；以及至少一种B块，其由不包含内酰胺环的乙烯单体或含有该单体的少量比例的单体得到；一种化妆品或药用组合物，如头发组合物，包括该共聚物；一种用于化妆或护理角蛋白材料的化妆过程，包括将该组合物涂抹到角蛋白材料上；以及该共聚物的其他用途。
• Block ethylenic copolymers comprising a vinyllactam block, cosmetic or pharmaceutical compositions comprising them and cosmetic use of these copolymers
  申请人：Mougin Nathalie

  公开号：US20050238594A1

  公开（公告）日：2005-10-27

  The present disclosure relates to linear block ethylenic copolymers that have reduced tack and thus do not leave a tacky feel, and to cosmetic and pharmaceutical compositions comprising the linear block ethylenic copolymer. Further disclosed herein is a cosmetic process for making up or caring for keratin materials, comprising the application to the keratin materials of such a composition, and also discloses herein are various cosmetic uses of such a composition. The tack of the copolymers disclosed herein is even reduced under conditions of high humidity, for example for RH values ranging from 50% to 100%.

  本公开涉及具有降低粘性的线性块状乙烯共聚物，因此不会留下粘性感，并且涉及包含线性块状乙烯共聚物的化妆品和药物组合物。此外，本文还公开了一种化妆过程，用于化妆或护理角蛋白材料，包括将该组合物应用于角蛋白材料，并且还公开了该组合物的各种化妆用途。本文所公开的共聚物的粘性甚至在高湿度条件下也得到了降低，例如在RH值为50％至100％的情况下。
• BLOCK ETHYLENIC COPOLYMERS COMPRISING A VINYLLACTAM BLOCK, COSMETIC COMPOSITIONS CONTAINING THEM AND COSMETIC USE OF THESE COPOLYMERS
  申请人：Mougin Nathalie

  公开号：US20100040572A1

  公开（公告）日：2010-02-18

  Linear block ethylenic copolymer comprising: at least one block A derived from monomers comprising from 52 to 100 % by weight of an ethylenic monomer containing a lactam ring corresponding to formula (I) below: and at least one block B derived from monomers not comprising an ethylenic monomer containing a lactam ring of formula (I), or comprising a minor proportion thereof, the at least one block B having a glass transition temperature Tg ranging from −55° C. to +55° C. Compositions and processes using the compound are also disclosed.

  线性块状乙烯共聚物包括：至少一个A块，由单体组成，其中单体包括52至100重量％的含有乳酸内酰胺环的乙烯单体，对应于下式（I）：以及至少一个B块，由不含有式（I）中的乙烯单体含有乳酸内酰胺环的单体或含有少量乙烯单体含有乳酸内酰胺环的单体组成，该至少一个B块的玻璃化转变温度Tg范围为-55℃至+55℃。还公开了使用该化合物的组合物和工艺。
• Block ethylenic copolymers comprising a vinyllactam block, cosmetic compositions containing them and cosmetic use of these copolymers
  申请人：Mougin Nathalie

  公开号：US20050101740A1

  公开（公告）日：2005-05-12

  Linear block ethylenic copolymer comprising: at least one block A derived from monomers comprising from 52 to 100% by weight of an ethylenic monomer containing a lactam ring corresponding to formula (I) below: and at least one block B derived from monomers not comprising an ethylenic monomer containing a lactam ring of formula (I), or comprising a minor proportion thereof, the at least one block B having a glass transition temperature Tg ranging from −55° C. to +55° C. Compositions and processes using the compound are also disclosed.

  线性块状乙烯共聚物，包括：至少一个A块，由含有内酰胺环的乙烯单体组成，其重量占52％至100％，对应于以下公式（I）：以及至少一个B块，由不含有公式（I）中所述内酰胺环的乙烯单体组成或含有其中少量的乙烯单体组成，所述至少一个B块的玻璃转移温度Tg范围为-55℃至+55℃。还公开了使用该化合物的组合物和工艺。
• LACTAMIC POLYMER CONTAINING AN ACETOACETATE MOIETY
  申请人：Hood David K.

  公开号：US20140296441A1

  公开（公告）日：2014-10-02

  The invention provides lactamic polymers comprising an acetoacetate moiety. The lactamic polymers may be readily functionalized and the functionalized lactamic polymers may be further derivatized to provide a wide variety of useful polymers having desirable chemical and physical properties. The lactamic polymers of the invention may be employed in a wide variety of compositions. (A); (B) wherein R 1 -R 6 , w, x, y, z, and n are described herein.

  该发明提供了含有乙酰乙酸酯基团的内酰胺聚合物。这些内酰胺聚合物可以很容易地进行官能化，并且官能化的内酰胺聚合物可以进一步衍生化，以提供具有理想化学和物理性质的各种有用聚合物。该发明的内酰胺聚合物可以用于各种组合物中。(A); (B)，其中R1-R6，w，x，y，z和n如本文所述。