(2,4,6-Trimethylbenzaldehyd)-2,4,6-trimethylanil | 17432-51-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (2,4,6-Trimethylbenzaldehyd)-2,4,6-trimethylanil
• 英文别名: N,1-bis(2,4,6-trimethylphenyl)methanimine
• CAS: 17432-51-8
• 化学式: C₁₉H₂₃N
• 分子量: 265.398
• InChiKey: NZRUYBVZVFQKDH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  12.4
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (2,4,6-Trimethylbenzaldehyd)-2,4,6-trimethylanil 在 氢气 、 Ba{N(SiMe3)2}2 作用下， 以 甲苯 为溶剂， 120.0 ℃ 、600.01 kPa 条件下， 反应 2.0h， 生成 2,4,6-trimethyl-N-[(2,4,6-trimethylphenyl)methyl]aniline
  参考文献：
  名称：

  氢化催化中的杂金属 Mg-Ba 氢化物簇

  摘要：

  异金属催化：已经制备了三种不同的 Mg/Ba 氢化物簇，并在固态和溶液中进行了研究。已经评估了 Mg 和 Ba 在加氢催化中的协同作用。

  DOI：

  10.1002/cctc.202101071

文献信息

• Exo- and endo-cyclopalladated compounds of N-benzylideneamines. Synthesis and X-ray structure of [P-2′,4′,6′-Me3C6H2)-3,5-Me2C6H2}Br]2
  作者：Jordi Barro、Jaume Granell、Daniel Sainz、Joaquim Sales、Mercè Font-Bardiá、Xavier Solans

  DOI：10.1016/0022-328x(93)83328-s

  日期：1993.8

  The action of Pd(AcO)2 on the imines C6RmH5-mCH=N(CH2)pC6Rn'H5-n has been studied. Five-membered endo-metallacycles were obtained from the imines 1a (R = 4-Cl, p = 0, R' = 2',4',6'-Me3) and lb (R = 2-Cl, p = 0, R'= 2',4',6'-Me3), by activation of a C(aromatic)-H bond and from the imine lc (R = 2,6-Cl 2, p = 0, R' = 2',4',6'-Me3), by oxidative addition of the ortho C-Cl bonds to Pd0 formed in situ. Six-membered endo-metallacycles were obtained from the imine 1d (R = 2,4,6-Me3, P = 0, R' = 2',4',6'-Me3) by activation of a C(aliphatic)-H bond. Imines le (R = 2,6-Cl2, p = 1, R' = 2'-Me) and If (R = 2,6-Cl2, P = 1, R'= 2'-Cl afforded five-membered exo-metallacycles, but the formation, in low yield, of the endo-compounds by oxidative addition of the ortho C-Cl bonds was also observed. These results show the strong tendency of imines to form endo-cyclic compounds. Complexes [PdBr(C N)(PPh3)] can be obtained by the action of PPh3 on the new cyclometallated compounds prepared. [Pd1-CH2-2-(CH=N-2',4',6'-Me3C6H2)-3,5-Me2C6H2}Br]2 Crystallizes in the monoclinic space group C2/c with a = 19.333(3); b = 13.511(2); c = 14.092(2) angstrom, beta = 96.94(2) and Z = 4. The endo six-membered ring displays a half-skew-chair conformation, with the palladium atom out of the plane (0.937 angstrom) defined by the other atoms.
• Heterometallic Mg−Ba Hydride Clusters in Hydrogenation Catalysis
  作者：Michael Wiesinger、Christian Knüpfer、Holger Elsen、Jonathan Mai、Jens Langer、Sjoerd Harder

  DOI：10.1002/cctc.202101071

  日期：2021.11.8

  Heterometallic catalysis: Three different Mg/Ba hydride clusters have been prepared and were studied in the solid state and in solution. Cooperative effects between Mg and Ba in hydrogenation catalysis have been evaluated.

  异金属催化：已经制备了三种不同的 Mg/Ba 氢化物簇，并在固态和溶液中进行了研究。已经评估了 Mg 和 Ba 在加氢催化中的协同作用。