morpholine-4-carbodithioic acid-(2-carbamoyl-ethyl ester) | 5337-31-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• 英文名称: morpholine-4-carbodithioic acid-(2-carbamoyl-ethyl ester)
• 英文别名: Morpholin-4-dithiocarbonsaeure-(2-carbamoyl-aethylester)；4-morpholinecarbodithioic acid, ester with 3-mercaptopropionamide；3-Amino-3-oxopropyl morpholine-4-carbodithioate；(3-amino-3-oxopropyl) morpholine-4-carbodithioate
• CAS: 5337-31-5
• 化学式: C₈H₁₄N₂O₂S₂
• mdl: MFCD02343841
• 分子量: 234.343
• InChiKey: VMKSKBVNNLLDDX-UHFFFAOYSA-N

物化性质

• 熔点：
  138.5 °C(Solv: water (7732-18-5))
• 沸点：
  451.8±55.0 °C(Predicted)
• 密度：
  1.335±0.06 g/cm3(Predicted)
• 溶解度：
  >35.1 [ug/mL]

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  113
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2-Cyanoethylmorpholinodithiocarbamat 在 硫酸 作用下， 生成 morpholine-4-carbodithioic acid-(2-carbamoyl-ethyl ester)
  参考文献：
  名称：

  Seyden-Penne, Annales de Chimie (Cachan, France), 1958, vol. <13>3, p. 599,631

  摘要：

  DOI：

文献信息

• Reactions of dithiocarbamic acids derived from alkaloids, morpholine, and piperidine with acrylic acid and its derivatices
  作者：T. S. Zhivotova、A. M. Gazaliev、M. K. Ibraev、S. D. Fazylov、R. Z. Kasenov

  DOI：10.1007/s11167-005-0022-8

  日期：2004.8

  β-(Thiocarbamoylthio)propionic acids derived from alkaloids, morpholine, and piperidine and their esters, amides, and nitriles were prepared by reactions of the corresponding dithiocarbamic acids with acrylic acid and its derivatives. Some of the compounds were tested for insecticidal activity.

  通过使相应的二硫代氨基甲酸与丙烯酸及其衍生物反应，可以制备得自生物碱，吗啉和哌啶的β-（硫代氨基甲酰硫基）丙酸及其酯，酰胺和腈。测试了某些化合物的杀虫活性。
• An expedient, fast and competent synthesis of organic dithiocarbamates over nanocrystalline MgO in water at room temperature
  作者：Bikash Karmakar、Julie Banerji

  DOI：10.1016/j.tetlet.2011.09.131

  日期：2011.12

  A new, expeditious, efficient and eco-friendly method for the synthesis of organic dithiocarbamates has been achieved at room temperature using basic nanocrystalline MgO catalyst in aqueous condition. The method has been applied for the synthesis of a range of compounds with variable functionalities in excellent yield and selectivity. (C)2011 Elsevier Ltd. All rights reserved.
• The Reaction of Dithiocarbamates with Acrylamide
  作者：Charles M. Buess

  DOI：10.1021/ja01629a057

  日期：1955.12