2,7-dibromo-9,9-bis(3-(propionic acid))fluorene | 94257-59-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,7-dibromo-9,9-bis(3-(propionic acid))fluorene
• 英文别名: 2,7-Dibrom-fluoren-di-propionsaeure-(9,9)；3,3'-(2,7-Dibromo-9H-fluorene-9,9-diyl)dipropanoic acid；3-[2,7-dibromo-9-(2-carboxyethyl)fluoren-9-yl]propanoic acid
• CAS: 94257-59-7
• 化学式: C₁₉H₁₆Br₂O₄
• 分子量: 468.142
• InChiKey: LZWOEPHIZWZPPV-UHFFFAOYSA-N

物化性质

• 熔点：
  300-302 °C(Solv: acetic acid (64-19-7))
• 沸点：
  648.2±45.0 °C(Predicted)
• 密度：
  1.692±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  25
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• 储存条件：
  存储条件：2-8°C，密封于干燥处。

反应信息

• 作为反应物：
  描述：

  2,7-dibromo-9,9-bis(3-(propionic acid))fluorene 在 硫酸 、 potassium acetate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 0.5h， 生成 2,7-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9,9-bis(3-((S)-2-methylbutyl propanoate))fluorene
  参考文献：
  名称：

  Design and Synthesis of Polymers for Chiral Photonics

  摘要：

  Chiral photonics deals with enantioselective polarization control of linear and nonlinear optical functions and holds a great promise for a wide range of applications including optical signal processing, biosensing and chiral bioimaging. Development of chiral materials with optical activity exceeding that of natural materials therefore becomes a prerequisite to,realizing the full potential of this field. Herein, we report on a study of structure-property relations of two chiral polymers with ester functional groups in lateral branch. To enhance rotational strength, the macroscopic measure of chirality, we employ a fluorene-quinoxaline motif in the monomer unit. To the best of our knowledge, we find the optical activity of one of the studied polymers to be the highest reported so far. Theoretical calculations reveal a correlation between the topological conformations and the simulated CD spectra in agreement with the experimental measurements and help clarify the mechanism of optical activity enhancement that could create insight for further enhancement of chirality.

  DOI：

  10.1021/ma401731x
• 作为产物：
  描述：

  2,7-二溴芴 在 四丁基溴化铵 、 三氟乙酸 、 sodium hydroxide 作用下， 以 二氯甲烷 、 甲苯 为溶剂， 生成 2,7-dibromo-9,9-bis(3-(propionic acid))fluorene
  参考文献：
  名称：

  溶剂激发的手性聚芴中的螺旋螺线感官偏倚。

  摘要：

  合成并表征了具有手性侧基的共轭均聚物聚（9,9-双（3-（（S）-2-甲基丁基丙酸酯））芴）（PSF）。溶解实验表明，PSF在高温下很好地溶解在消旋mon烯中，并在顺序冷却处理后开始聚集。通过旋涂法将相应的组件转移到石英板上。相比之下，还制备了由氯仿溶液流延的薄膜。经过退火热处理后，这些PSF膜表现出完美的镜面圆二色性（CD）棉花效应和不对称率。光学吸收光谱（UV-vis），CD和荧光光谱结果表明手性侧链成功诱导了M-和P聚集体和薄膜中的螺旋结构，这种显着差异归因于它们不同的超分子构象。

  DOI：

  10.1002/chir.22677

文献信息

• Novel reagents for directed biomarker signal amplification
  申请人：Gaylord Brent S.

  公开号：US20110256549A1

  公开（公告）日：2011-10-20

  Described herein are methods, compositions and articles of manufacture involving neutral conjugated polymers including methods for synthesis of neutral conjugated water-soluble polymers with linkers along the polymer main chain structure and terminal end capping units. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.

  本文描述了涉及中性共轭聚合物的方法、组合物和制造物品，包括合成具有连接物的中性共轭水溶性聚合物的方法，连接物沿聚合物主链结构和末端封端单元。这种聚合物可用于制备新型光电子器件，并在高效生物传感器的开发中发挥作用。该发明进一步涉及这些聚合物在测定方法中的应用。
• Novel Reagents for Directed Biomarker Signal Amplification
  申请人：Gaylord Brent S.

  公开号：US20110257374A1

  公开（公告）日：2011-10-20

  Described herein are methods, compositions and articles of manufacture involving neutral conjugated polymers including methods for synthesis of neutral conjugated water-soluble polymers with linkers along the polymer main chain structure and terminal end capping units. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.

  本文描述了涉及中性共轭聚合物的方法、组合物和制造品，包括合成带有连接物的中性共轭水溶性聚合物的方法，以及端基封闭单元。这些聚合物可用于制造新型光电器件，以及开发高效的生物传感器。本发明进一步涉及这些聚合物在测定方法中的应用。
• Reagents for directed biomarker signal amplification
  申请人：Gaylord Brent S.

  公开号：US08362193B2

  公开（公告）日：2013-01-29

  Described herein are methods, compositions and articles of manufacture involving neutral conjugated polymers including methods for synthesis of neutral conjugated water-soluble polymers with linkers along the polymer main chain structure and terminal end capping units. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.

  本文描述了涉及中性共轭聚合物的方法、组合物和制造品，包括合成带有连接物的中性共轭水溶性聚合物的方法，以及端基覆盖单元。这种聚合物可以用于制造新型光电器件和高效生物传感器的开发。本发明还涉及这些聚合物在测定方法中的应用。
• Layered structure comprising a layer containing a conjugated polymer compound
  申请人：Tanaka Masanobu

  公开号：US08951646B2

  公开（公告）日：2015-02-10

  A layered structure including a first electrode and a second electrode, a light-emitting layer or a charge separation layer between the first electrode and the second electrode, and a layer containing a conjugated polymer compound between the light-emitting layer or the charge separation layer and the first electrode, wherein the conjugated polymer compound contains a repeating unit selected from the group consisting of a repeating unit of formula (1).

  一个分层结构，包括第一电极和第二电极，第一电极和第二电极之间有一个发光层或电荷分离层，发光层或电荷分离层和第一电极之间有一个含有共轭聚合物化合物的层，其中共轭聚合物化合物包含从公式（1）的重复单元组成的重复单元。
• LAYERED STRUCTURE
  申请人：Tanaka Masanobu

  公开号：US20110006294A1

  公开（公告）日：2011-01-13

  Disclosed is a layered structure including a first electrode and a second electrode, a light-emitting layer or a charge separation layer between the first electrode and the second electrode, and a layer containing a conjugated polymer compound between the light-emitting layer or the charge separation layer and the first electrode, wherein the conjugated polymer compound contains a repeating unit selected from the group consisting of a repeating unit represented by formula (1): wherein Ar 1 represents a divalent aromatic group, R 1 represents a substituent group having a group represented by formula (2), Ar 1 may have a substituent group other than R 1 , and n1 represents an integer of 1 or more; -(R 2 ) c1 -(Q 1 ) n2 -Y 1 (M 1 ) a1 (Z 1 ) b1 (2) wherein R 2 represents a divalent aromatic group which may have a substituent group, Q 1 represents a divalent organic group which may have a substituent group, Y 1 represents a carbocation, an ammonium cation, a phosphonyl cation or a sulfonyl cation, M 1 represents F − , Cl − , Br − , I − , OH − , R a SO 3 − , R a COO − , ClO − , ClO 2 − , ClO 3 − , ClO 4 − , SCN − , CN − , NO 3 − , SO 4 2− , HSO 4 − , PO 4 3− , HPO 4 2− , H 2 PO 4 − , BF 4 − or PF 6 − , Z 1 represents a metal ion or an ammonium ion which may have a substituent group, c1 represents 0 or 1, n2 represents an integer of 0 or more, provided that n2 is 0 when c1 is 0, a1 represents an integer of 1 or more, b1 represents an integer of 0 or more, a1 and b1 are selected so that the charge of the substituent group represented by formula (2) is 0, R a represents an alkyl group having 1 to 30 carbon atoms, which may have a substituent group, or an aryl group having 6 to 50 carbon atoms, which may have a substituent group.

  本发明公开了一种分层结构，包括第一电极和第二电极，第一电极和第二电极之间有一个发光层或电荷分离层，发光层或电荷分离层和第一电极之间含有一层含有共轭聚合物化合物的层，其中所述的共轭聚合物化合物包含从由式(1)表示的重复单元所选的重复单元组中选出的一个重复单元： 式中，Ar1表示一个二价芳香基团，R1表示一个具有由式(2)表示的基团的取代基团，Ar1可能具有除R1以外的取代基团，n1表示1或更多的整数； -(R2)c1-(Q1)n2-Y1(M1)a1(Z1)b1(2) 式中，R2表示一个二价芳香基团，它可能具有取代基团，Q1表示一个二价有机基团，它可能具有取代基团，Y1表示一个碳正离子、铵离子、磷酰阳离子或磺酰阳离子，M1表示F−、Cl−、Br−、I−、OH−、RaSO3−、RaCOO−、ClO−、ClO2−、ClO3−、ClO4−、SCN−、CN−、NO3−、SO42−、HSO4−、PO43−、HPO42−、H2PO4−、BF4−或PF6−，Z1表示一个金属离子或铵离子，它可能具有取代基团，c1表示0或1，n2表示0或更多的整数，当c1为0时，n2为0，a1表示1或更多的整数，b1表示0或更多的整数，a1和b1被选择为使式(2)所表示的取代基团的电荷为0，Ra表示一个具有1到30个碳原子的烷基，它可能具有取代基团，或者一个具有6到50个碳原子的芳基，它可能具有取代基团。