2-{[bis(pyrid-2-ylmethyl)amino]methyl}-6-{[(3,5-di-tert-butyl-2-hydroxybenzyl)(pyrid-2-ylmethyl)amino]methyl}-4-methylphenol | 896420-67-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-{[bis(pyrid-2-ylmethyl)amino]methyl}-6-{[(3,5-di-tert-butyl-2-hydroxybenzyl)(pyrid-2-ylmethyl)amino]methyl}-4-methylphenol
• 英文别名: 2-[N,N-bis-(2-pyridylmethyl)aminomethyl]-6-[N-(3,5-di-tert-butyl-2-oxidobenzyl)-N-(2-pyridylamino)aminomethyl]-4-methylphenol；[2-[N,N-bis(2-pyridylmethyl)aminomethyl]-6-[N',N'-(3,5-di-tert-butylbenzyl-2-hydroxy)(2-pyridylmethyl)]aminomethyl]-4-methylpheol；{2-[N,N-bis(2-pyridylmethyl)aminomethyl]-6-[N',N'-(3,5-di-tert-butylbenzyl-2-hydroxy)(2-pyridylmethyl)]aminomethyl}-4-methylphenol；2-[[Bis(pyridin-2-ylmethyl)amino]methyl]-6-[[(3,5-ditert-butyl-2-hydroxyphenyl)methyl-(pyridin-2-ylmethyl)amino]methyl]-4-methylphenol；2-[[bis(pyridin-2-ylmethyl)amino]methyl]-6-[[(3,5-ditert-butyl-2-hydroxyphenyl)methyl-(pyridin-2-ylmethyl)amino]methyl]-4-methylphenol
• CAS: 896420-67-0
• 化学式: C₄₂H₅₁N₅O₂
• 分子量: 657.899
• InChiKey: PJVHLMRYGLSDSU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.5
• 重原子数：
  49
• 可旋转键数：
  14
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  85.6
• 氢给体数：
  2
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  2-{[bis(pyrid-2-ylmethyl)amino]methyl}-6-{[(3,5-di-tert-butyl-2-hydroxybenzyl)(pyrid-2-ylmethyl)amino]methyl}-4-methylphenol 、 sodium perchlorate monohydrate 、 manganese(III) triacetate dihydrate 以 乙醇 、 水 为溶剂， 以52%的产率得到[Mn2(2-[[bis(pyrid-2-ylmethyl)amino]methyl]-6-[[(3,5-di-tert-butyl-2-hydroxybenzyl)(pyrid-2-ylmethyl)amino]methyl]-4-methylphenol
  参考文献：
  名称：

  具有不对称配体的二锰 (II,III) 配合物的氧化还原化学：水结合、去质子化和累积光诱导氧化

  摘要：

  已合成双核锰络合物 {[(Mn2L)-L-II,IIII(mu-OAc)(2)]-ClO4}，其中 L 是 2-{[bis-(pyrid-2-ylmethyl)氨基]甲基}-6-{[(3,5-二叔丁基-2-羟基苄基)(p ...

  DOI：

  10.1002/ejic.200600676
• 作为产物：
  描述：

  3-(氯甲基)-2-羟基-5-甲基苯甲醛 在 sodium tetrahydroborate 、 氯化亚砜 、 三乙胺 作用下， 以 甲醇 、 二氯甲烷 为溶剂， 反应 2.5h， 生成 2-{[bis(pyrid-2-ylmethyl)amino]methyl}-6-{[(3,5-di-tert-butyl-2-hydroxybenzyl)(pyrid-2-ylmethyl)amino]methyl}-4-methylphenol
  参考文献：
  名称：

  具有不对称配体的二锰 (II,III) 配合物的氧化还原化学：水结合、去质子化和累积光诱导氧化

  摘要：

  已合成双核锰络合物 {[(Mn2L)-L-II,IIII(mu-OAc)(2)]-ClO4}，其中 L 是 2-{[bis-(pyrid-2-ylmethyl)氨基]甲基}-6-{[(3,5-二叔丁基-2-羟基苄基)(p ...

  DOI：

  10.1002/ejic.200600676

文献信息

• Development of a biomimetic chitosan film-coated gold electrode for determination of dopamine in the presence of ascorbic acid and uric acid
  作者：Suellen Cadorin Fernandes、Iolanda Cruz Vieira、Rosely A. Peralta、Ademir Neves

  DOI：10.1016/j.electacta.2010.06.062

  日期：2010.9

  A gold electrode surface was modified using a dinuclear copper complex [Cu-2(II) (Ldtb)(mu-OCH3)](BPh4) and then coated with a chitosan film. This biomimetic polymer film-coated electrode was employed to eliminate the interference from ascorbic acid and uric acid in the sensitive and selective determination of dopamine. The optimized conditions obtained for the biomimetic electrode were 0.1 M phosphate buffer solution (pH 8.0), complex concentration of 2.0 x 10(-4) M, 0.1% of chitosan and 0.25% of glyoxal. Under the optimum conditions, the calibration curve was linear in the concentration range of 4.99 x 10(-7) to 1.92 x 10(-5) M, and detection and quantification limits were 3.57 x 10(-7) M and 1.07 x 10(-6) M. respectively. The recovery study gave values of 95.2-102.6%. The lifetime of this biomimetic sensor showed apparent loss of activity after 70 determinations. The results obtained with the modified electrode for dopamine quantification in the injection solution matrix were in good agreement with those of the pharmacopoeia method. (C) 2010 Elsevier Ltd. All rights reserved.
• A mixed-valence diacetate-bridged Mn^II–Mn^IIIcomplex incorporating a bridging phenolate ligand
  作者：Adailton J. Bortoluzzi、Ademir Neves、Ricardo A. A. Couto、Rosely A. Peralta

  DOI：10.1107/s0108270105039910

  日期：2006.2.15

  The synthesis and characterization of a new unsymmetrical dinucleating N,O-donor ligand, 2-[N,N-bis(2-pyridylmethyl)aminomethyl]-6-[N-(3,5-di-tert-butyl-2-oxidobenzyl)-N-(2-pyridylamino)aminomethyl]-4-methylphenol (H(2)Ldtb), as well as the X-ray crystal structure of its corresponding mixed-valence diacetate-bridged manganese complex, di-mu-acetato-mu-2-[ N,N- bis(2-pyridylmethyl)aminomethyl]-6-[ N-(3,5-di-tert-butyl-2-oxidobenzyl)-N-(2-pyridylamino)aminomethyl]-4-methyl-phenolato}dimanganese(II,III) tetraphenylborate, [Mn-II-Mn-III(C42H49N5O2)(C2H3O2)(2)](C24H20B), are reported. The complex may be regarded as an interesting structural model for the mixed-valence Mn-II-Mn-III state of manganese catalase.
• Redox Chemistry of a Dimanganese(II,III) Complex with an Unsymmetric Ligand: Water Binding, Deprotonation and Accumulative Light‐Induced Oxidation
  作者：Magnus F. Anderlund、Joakim Högblom、Wei Shi、Ping Huang、Lars Eriksson、Högni Weihe、Stenbjörn Styring、Björn Åkermark、Reiner Lomoth、Ann Magnuson

  DOI：10.1002/ejic.200600676

  日期：2006.12

  A dinuclear manganese complex [(Mn2L)-L-II,IIII(mu-OAc)(2)]-ClO4} has been synthesised, where L is the dianion of 2-[bis-(pyrid-2-ylmethyl)amino]methyl}-6-[(3,5-di-tert-butyl-2- hydroxybenzyl)(p ...

  已合成双核锰络合物 [(Mn2L)-L-II,IIII(mu-OAc)(2)]-ClO4}，其中 L 是 2-[bis-(pyrid-2-ylmethyl)氨基]甲基}-6-[(3,5-二叔丁基-2-羟基苄基)(p ...