2-Butoxy-1,3-difluorobenzene | 946078-88-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2-Butoxy-1,3-difluorobenzene
• 英文别名: 2-butoxy-1,3-difluorobenzene
• CAS: 946078-88-2
• 化学式: C₁₀H₁₂F₂O
• 分子量: 186.2
• InChiKey: RBURNMPAOIOGDF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• FUNGICIDAL AZOCYCLIC AMIDES
  申请人：Hanagan Mary Ann

  公开号：US20130261154A1

  公开（公告）日：2013-10-03

  Disclosed are compounds of Formula 1, including all stereoisomers, N-oxides, and salts thereof, wherein E, X, G, J, Z, and Q are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention.

  本发明揭示了公式1的化合物，包括所有立体异构体，N-氧化物和其盐，其中E，X，G，J，Z和Q的定义如披露所述。本发明还揭示了含有公式1化合物的组合物，并且揭示了控制由真菌病原体引起的植物病害的方法，包括施用本发明的化合物或组合物的有效量。
• ARGINASE INHIBITORS AND METHODS OF USE
  申请人：THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA

  公开号：US20160194340A1

  公开（公告）日：2016-07-07

  The present invention is directed to arginase inhibitor compounds of formula IA or formula IB: or a pharmaceutically acceptable salt thereof, compositions containing these compounds, and methods of their use for the treatment and diagnosis of conditions characterized by upregulation of arginase, abnormally high arginase activity, or by abnormally low nitric oxide synthase activity.

  本发明涉及式IA或式IB的精氨酸酶抑制剂化合物：或其药学上可接受的盐，包含这些化合物的组合物，以及它们用于治疗和诊断由精氨酸酶上调，异常高的精氨酸酶活性或异常低的一氧化氮合成酶活性所特征的疾病的方法。
• Arginase Inhibitors and Methods of Use
  申请人：AstraZeneca AB

  公开号：US20190127395A1

  公开（公告）日：2019-05-02

  The present invention is directed to arginase inhibitor compounds of formula IA or formula IB: or a pharmaceutically acceptable salt thereof, compositions containing these compounds, and methods of their use for the treatment and diagnosis of conditions characterized by upregulation of arginase, abnormally high arginase activity, or by abnormally low nitric oxide synthase activity.