3-[(2,4-Dihydroxy-3,3-dimethylbutanoyl)amino]propyl acetate | 32484-53-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 3-[(2,4-Dihydroxy-3,3-dimethylbutanoyl)amino]propyl acetate
• 英文别名: 3-[(2,4-dihydroxy-3,3-dimethylbutanoyl)amino]propyl acetate
• CAS: 32484-53-0
• 化学式: C₁₁H₂₁NO₅
• 分子量: 247.291
• InChiKey: ZHXFLNLRFSRHHE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  17
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  95.9
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  DL-泛醇 、 醋酸异丙酯 在 Novozyme 435 作用下， 以 乙腈 为溶剂， 反应 0.5h， 生成 3-[(2,4-Dihydroxy-3,3-dimethylbutanoyl)amino]propyl acetate
  参考文献：
  名称：

  Selective synthesis of panthenyl esters by a kinetically controlled enzymatic process

  摘要：

  Panthenyl esters (panthenyl monoacetate and panthenyl diacetate) were synthesized in high yields (approximate to 100%) by a kinetic reaction control using a commercial immobilized Candida Antarctica lipase B (Novozyme 435) in acetonitrile. The enzyme showed excellent synthetic activity, regioselectivity, and operational stability under the conditions used.

  DOI：

  10.3109/10242422.2013.814644

文献信息

• CONJUGATE OF FINE POROUS PARTICLES WITH POLYMER MOLECULES AND UTILIZATION THEREOF
  申请人：Tokyo University of Science, Educational Foundation

  公开号：EP1645597A1

  公开（公告）日：2006-04-12

  A conjugate which comprises fine porous particles (on which functional substance may be adhered) and a polymer based on water-soluble high molecular chain segment, and the use of the conjugate (for the purpose of stably supporting, or slowly releasing, a physiologically active substance, or the like).

  由细微多孔颗粒（其上可粘附功能物质）和基于水溶性高分子链段的聚合物组成的共轭物，以及该共轭物的用途（用于稳定支撑或缓慢释放生理活性物质等）。
• Conjugate of fine porous particles with polymer molecules and the utilization thereof
  申请人：Nagasaki Yukio

  公开号：US20060159715A1

  公开（公告）日：2006-07-20

  A conjugate which comprises fine porous particles (on which functional substance may be adhered) and a polymer based on water-soluble high molecular chain segment, and the use of the conjugate (for the purpose of stably supporting, or slowly releasing, a physiologically active substance, or the like).

  由细微多孔颗粒（其上可粘附功能物质）和基于水溶性高分子链段的聚合物组成的共轭物，以及该共轭物的用途（用于稳定支撑或缓慢释放生理活性物质等）。
• Selective synthesis of panthenyl esters by a kinetically controlled enzymatic process
  作者：Teresa De Diego、Arturo Manjón、José L. Iborra

  DOI：10.3109/10242422.2013.814644

  日期：2013.8

  Panthenyl esters (panthenyl monoacetate and panthenyl diacetate) were synthesized in high yields (approximate to 100%) by a kinetic reaction control using a commercial immobilized Candida Antarctica lipase B (Novozyme 435) in acetonitrile. The enzyme showed excellent synthetic activity, regioselectivity, and operational stability under the conditions used.