5-bromopentyl formate | 1233324-44-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 5-bromopentyl formate
• CAS: 1233324-44-1
• 化学式: C₆H₁₁BrO₂
• 分子量: 195.056
• InChiKey: JXGAKBTXTXZRQA-UHFFFAOYSA-N

物化性质

• 沸点：
  211.3±23.0 °C(Predicted)
• 密度：
  1.350±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  9
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  6-溴己醛 在 水 、 p-(trifluoromethyl)phenyl(difluoro)-λ3-bromane 作用下， 以 二氯甲烷 为溶剂， 反应 3.0h， 以55%的产率得到5-bromopentyl formate
  参考文献：
  名称：

  Baeyer-Villiger 氧化的高价 λ3-溴烷策略：初级脂肪族和芳香族醛向甲酸盐的选择性转化，这在经典的 Baeyer-Villiger 氧化中是缺失的

  摘要：

  Baeyer-Villiger 氧化 (BVO) 的概念独特的现代策略被开发出来。我们的新方法涉及将水初始水合为羰基化合物，然后将溴烷 (III) 上的高价芳基-λ(3)-溴烷与所得水合物进行配体交换，从而产生一种新型的活化 Criegee 中间体。由于超核，中间体经历 BV 重排并通过芳基-λ(3)-溴基的轻松还原消除产生酯。这种新策略可以选择性地诱导直链脂肪族和芳香族伯醛的 BV 重排，这在经典 BVO 中是缺失的：例如，辛醛和苯甲醛提供了高选择性（> 95%）的重排甲酸酯我们的条件，而尝试的经典 BVO 仅产生羧酸。这牢固地确立了 BVO 新方法论的强大性质。

  DOI：

  10.1021/ja104330g

文献信息

• 3-(4,5-Dihydroisoxaxol-5-yl)benzoylcyclohexenones and the use thereof as herbicides
  申请人：——

  公开号：US20030199699A1

  公开（公告）日：2003-10-23

  The invention relates to 3-(4,5-dihydroisoxazole-5-yl)benzoylcyclohexenones of the general formula (I), wherein the variables have the following meanings: R 1 , R 2 represents hydrogen, nitro, halogen, cyano, alkyl, haloalkyl, alkoxy, haloalkoxy, alkylthio, haloalkylthio, alkylsulfinyl, haloalkylsulfinyl, alkysulfonyl or C 1 -C 6 haloalkylsulfonyl; R 3 represents hydrogen, halogen or alkyl; R 4 represents hydrogen or alkyl; R 5 , R 6 represents hydrogen, halogen, cyano, nitro, alkyl, alkoxy, alkylthio, dialkylamino, phenyl, benzyl or carbonyl, wherein the 7 last residues can be substituted; R 11 represents optionally substituted cyclohexenone that is linked in the 2 position and that carries a hydroxy residue or derivatives thereof in the 1 position. The invention further relates to the agriculturally useful salts thereof, to methods for producing the 3-(4,5-dihydroisoxazole-5-yl)benzoylcyclohexenones, to agents that contain the inventive compound, and to the use of said derivatives or agents containing them for controlling undesired plants.

  该发明涉及通式（I）的3-(4,5-二氢异噁唑-5-基)苯甲酰环己烯酮，其中变量具有以下含义：R1，R2代表氢、硝基、卤素、氰基、烷基、卤代烷基、烷氧基、卤代烷氧基、烷硫基、卤代烷硫基、烷基磺酰基、卤代烷基磺酰基或C1-C6卤代烷基磺酰基；R3代表氢、卤素或烷基；R4代表氢或烷基；R5，R6代表氢、卤素、氰基、硝基、烷基、烷氧基、烷硫基、二烷基氨基、苯基、苄基或羰基，其中最后7个残基可以被取代；R11代表在2位连接的可选择取代的环己烯酮，在1位携带一个羟基残基或其衍生物。该发明还涉及其农业上有用的盐，生产3-(4,5-二氢异噁唑-5-基)苯甲酰环己烯酮的方法，含有该创新化合物的药剂，以及用于控制不受欢迎植物的衍生物或含有它们的药剂的用途。
• 5[(pyrazol-4-yl)carbonyl]benzazolone as herbicide
  申请人：——

  公开号：US20040033899A1

  公开（公告）日：2004-02-19

  Pyrazolylbenzazolones of the formula I 1 where the variables R 1 , R 2 , R 3 , A and Pz are as defined in claim 1 , and their salts, and their use for controlling harmful plants, are described.

  本文描述了式I1中变量R1，R2，R3，A和Pz如权利要求1所定义的吡唑基苯并咪唑酮及其盐的使用，用于控制有害植物。
• Benzazolonylcarbonylcyclohexenones and their use ss herbicides
  申请人：——

  公开号：US20040063584A1

  公开（公告）日：2004-04-01

  Cyclohexenone derivatives of benzazolones of the formula I 1 where the variables R 1 , R 2 , R 3 , A and Hex are as defined in claim 1, and their salts, and their use for controlling harmful plants, are described.

  本发明涉及苯并咪唑酮的环己烯酮衍生物，其化学式为I1，其中变量R1，R2，R3，A和Hex如权利要求1所定义，以及它们的盐，以及它们用于控制有害植物的用途。
• TRICYCLIC BENZOYLPYRAZOLE DERIVATIVES
  申请人：Witschel Matthias

  公开号：US20070197393A1

  公开（公告）日：2007-08-23

  Tricyclic benzoylpyrazole derivatives of the formula I where: X is oxygen, sulfur, S═O, S(═O) 2 , CR 6 R 7 , NR 8 or a bond; Y together with the two carbons to which it is attached forms a saturated, partially saturated or unsaturated 5- or 6-membered heterocycle; R 1 , R 2 , R 6 , R 7 are hydrogen, alkyl, haloalkyl, alkoxy or haloalkoxy; R 3 is halogen, alkyl, haloalkyl, alkoxy or haloalkoxy; R 4 is hydrogen, nitro, halogen, cyano, alkyl, haloalkyl, alkoxy, haloalkoxy, alkylthio, haloalkylthio, alkylsulfinyl, haloalkylsulfinyl, alkylsulfonyl, haloalkylsulfonyl, unsubstituted or substituted aminosulfonyl or unsubstituted or substituted sulfonylamino; R 5 is hydrogen, alkyl or halogen; l is 0, 1 or 2; R 8 is hydrogen, alkyl, haloalkyl, alkylcarbonyl, formyl, alkoxycarbonyl, haloalkoxycarbonyl, alkylsulfonyl or haloalkylsulfonyl; R 9 is substituted pyrazol-4-ylcarbonyl or substituted 5-oxopyrazolin-4-ylmethylidene; and their agriculturally useful salts; processes and intermediates for preparing the tricyclic benzoylpyrazole derivatives; compositions comprising them and the use of these derivatives or of the compositions comprising them for controlling undesirable plants are described.

  化合物I的三环苯甲酰吡唑衍生物的公式为：其中：X是氧、硫、S═O、S（═O）2、CR6R7、NR8或键；Y与其连接的两个碳原子形成饱和、部分饱和或不饱和的5-或6元杂环；R1、R2、R6、R7为氢、烷基、卤代烷基、烷氧基或卤代烷氧基；R3为卤素、烷基、卤代烷基、烷氧基或卤代烷氧基；R4为氢、硝基、卤素、氰基、烷基、卤代烷基、烷氧基、卤代烷氧基、烷基硫基、卤代烷基硫基、烷基亚磺酰基、卤代烷基亚磺酰基、烷基磺酰基、卤代烷基磺酰基、未取代或取代的氨基磺酰基或未取代或取代的磺酰胺基；R5为氢、烷基或卤素；l为0、1或2；R8为氢、烷基、卤代烷基、烷基羰基、甲酰基、烷氧羰基、卤代烷氧羰基、烷基磺酰基或卤代烷基磺酰基；R9为取代的吡唑-4-基羰基或取代的5-氧代吡唑-4-基甲基亚胺基；以及它们的农业有用盐；描述了制备这些三环苯甲酰吡唑衍生物的过程和中间体；包含它们的组合物以及使用这些衍生物或包含它们的组合物来控制不良植物的用途。
• Novel polymer and method for determining cholesterol using the same
  申请人：Wako Pure Chemical Industries, Ltd.

  公开号：EP2239281A2

  公开（公告）日：2010-10-13

  It is an object of the present invention to provide the method for determining cholesterol in lipoprotein and reagent for determining cholesterol comprising the polymer, and the present invention relates to the reagent for determining cholesterol in lipoproteins such as high-density lipoprotein (HDL), low-density lipoprotein(LDL) and very low-density lipoprotein(VLDL) and the determination method using the polymer comprising the following units as constituents: (iv) a polyethylene glycol segment represented by the general formula [1]:         -(CH2CH2O)k-     [1] (wherein, k represents an integer of 10 to 250); (v) a monomer unit represented by the general formula [2]: (wherein R1 represents a hydrogen atom or C1-C3 alkyl group); and (vi) a monomer unit represented by the general formula [3]: [wherein, R2 represents a hydrogen atom or C1-C3 alkyl group, and R3 represents a group represented by the general formula [4]:         -COOR4     [4] (wherein, R4 represents an alkyl group, a haloalkyl group or a bornyl group), an alkyl group, an alkoxy group, an aralkyl group or an alkylcarbamoyl group; particularly, in the direct measurement of cholesterols such as HDL, LDL and VLDL contained in the sample, the reagent for determining cholesterol in the presence of said polymer, and the method for determining the concentration of cholesterol in a specific lipoprotein using said reagent for determining cholesterol, and a novel polymer.

  本发明的目的是提供测定脂蛋白中胆固醇的方法和由聚合物组成的测定胆固醇的试剂，本发明涉及测定高密度脂蛋白(HDL)、低密度脂蛋白(LDL)和极低密度脂蛋白(VLDL)等脂蛋白中胆固醇的试剂和使用由下列单元组成的聚合物作为成分的测定方法： (iv) 由通式[1]表示的聚乙二醇段： -(CH2CH2O)k-[1]。 (其中，k 代表 10 至 250 的整数）； (v) 由通式[2]表示的单体单元： (其中 R1 代表氢原子或 C1-C3 烷基）；以及 (vi) 由通式[3]代表的单体单元： [其中，R2 代表氢原子或 C1-C3 烷基，R3 代表通式[4]所代表的基团： -COOR4[4]代表的基团 (其中，R4 代表烷基、卤代烷基或伯烷基）、烷基、烷氧基、芳烷基或烷基氨基甲酰基；特别是，在直接测定样品中所含胆固醇如高密度脂蛋白、低密度脂蛋白和超低密度脂蛋白时，在所述聚合物存在下测定胆固醇的试剂，以及使用所述测定胆固醇的试剂测定特定脂蛋白中胆固醇浓度的方法，以及一种新型聚合物。