5,6'-dimethyl-2,2'-bipyridine | 245678-74-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 5,6'-dimethyl-2,2'-bipyridine
• 英文别名: 2-methyl-6-(5-methylpyridin-2-yl)pyridine
• CAS: 245678-74-4
• 化学式: C₁₂H₁₂N₂
• 分子量: 184.241
• InChiKey: UZQWGNYSJZOTNB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  25.8
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  5,6'-dimethyl-2,2'-bipyridine 在 potassium dichromate 、 硫酸 、 水 、 硝酸 作用下， 反应 36.0h， 以20%的产率得到2,2'-bipyridine-5,6'-dicarboxylic acid
  参考文献：
  名称：

  A simple and environmentally benign synthesis of polypyridine-polycarboxylic acids

  摘要：

  An oxidation method using dilute nitric acid solutions under solvothermal conditions has been developed to synthesise a series of polypyridine-polycarboxylic acids. It has been successfully applied to a range of methyl substituted polypyridines including symmetrical and asymmetrical 2,2'-bipyridines; 2,2':6',2 ''-terpyridines and; 2,2':6',2 '':6 '',2'''-tetra-pyridines and yields crystalline polypyridine-polycarboxylic acids in a single step. Simple product recovery through filtration yields a recyclable filtrate. More forcing conditions led to demethylation of the polypyridine ligand most probably via decarboxylation. This simple approach avoids potentially harmful metal-based oxidants and negates any issues associated with the disposal of their resultant (hazardous) waste. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.12.074
• 作为产物：
  描述：

  2-氨基-5-甲基吡啶 在 四(三苯基膦)钯 溴 作用下， 以 甲苯 为溶剂， 反应 49.5h， 生成 5,6'-dimethyl-2,2'-bipyridine
  参考文献：
  名称：

  斯蒂勒型交叉偶联-一种有效的方法来制备各种对称和不对称取代的甲基联吡啶：面向新型ATRP催化剂

  摘要：

  利用Stille型偶联方法，高收率和数克级合成了各种单取代和二取代的2,2'-联吡啶。相应的溴-甲基吡啶和三丁基锡-甲基吡啶是由可商购的氨基-甲基吡啶化合物制备的。作为金属络合物的第一个例子，使4,5'-二甲基-2,2'-联吡啶与铜（II）和铁（II）离子反应，并作为ATRP的催化剂进行研究。

  DOI：

  10.1021/ol006473s

文献信息

• ORGANIC ELECTROLUMINESCENT DEVICE
  申请人：Soga Masayuki

  公开号：US20120199825A1

  公开（公告）日：2012-08-09

  An organic electroluminescent device comprising an anode, a cathode, a light emitting layer that is disposed between the anode and the cathode and contains a first light emitting layer material containing a phosphorescent compound and a second light emitting layer material containing a charge transporting polymer compound (that is, a light emitting layer containing a first light emitting layer material and a second light emitting layer material), and a hole transporting layer that is disposed between the anode and the light emitting layer so as to be adjacent to the light emitting layer and is composed of a hole transporting polymer compound, wherein the lowest excitation triplet energy T1 e (eV) of the first light emitting layer material, the lowest excitation triplet energy T1 h (eV) of the second light emitting layer material and the lowest excitation triplet energy T1 t (eV) of the hole transporting polymer compound satisfy the following formulae (A) and (B): T 1 e ≦T 1 h (A) T 1 t −T 1 e ≦0.10  (B). An organic electroluminescent device comprising an anode and a cathode, and a hole transporting layer and a light emitting layer disposed between the anode and the cathode, wherein the hole transporting layer contains 1) a mixture of 2,2′-bipyridine and/or 2,2′-bipyridine derivative and a non-2,2′-bipyridinediyl group-containing hole transporting polymer compound, 2) a 2,2′-bipyridinediyl group-containing polymer compound having a constitutional unit composed of an unsubstituted or substituted 2,2′-bipyridinediyl group, and at least one constitutional unit selected from the group consisting of constitutional units composed of a divalent aromatic amine residue and constitutional units composed of an unsubstituted or substituted arylene group, or a combination thereof.

  一种有机电致发光器件，包括阳极、阴极、位于阳极和阴极之间且含有第一发光层材料和第二发光层材料的发光层（即含有第一发光层材料和第二发光层材料的发光层），其中第一发光层材料含有磷光化合物，第二发光层材料含有电荷传输聚合物化合物，以及位于阳极和发光层之间以与发光层相邻的方式设置的孔传输层，由孔传输聚合物化合物组成，其中第一发光层材料的最低激发三重态能量T1e（eV）、第二发光层材料的最低激发三重态能量T1h（eV）和孔传输聚合物化合物的最低激发三重态能量T1t（eV）满足以下公式（A）和（B）：T1e≦T1h（A）T1t−T1e≦0.10（B）。一种有机电致发光器件，包括阳极和阴极、孔传输层和发光层，位于阳极和阴极之间，其中孔传输层包含1）2,2′-联吡啶和/或2,2′-联吡啶衍生物的混合物和不含2,2′-联吡啶基团的孔传输聚合物化合物，2）具有由未取代或取代的2,2′-联吡啶基团组成的构成单元和至少选自由双价芳香胺残基和由未取代或取代的芳基烃基组成的构成单元之一的构成单元的2,2′-联吡啶基团含量聚合物化合物，或其组合。
• POLYMERIC COMPOUND HAVING RESIDUE OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUND
  申请人：Anryu Makoto

  公开号：US20110118411A1

  公开（公告）日：2011-05-19

  A polymer compound having a residue of a compound represented by the following formula (1): wherein Ar represents an aryl group or mono-valent heterocyclic group.) and a residue of a compound represented by the following formula (2): wherein one member of Z 1 to Z 3 represents —N═ and two remainders thereof each represent —C(R′)═. Z 4 and Z 5 each represent —C(R′)═. One member of Z 6 to Z 8 represents —N═ and two remainders thereof each represent —C(R′)═. Z 9 and Z 10 each represent —C(R′)═. R′ represents a hydrogen atom, alkyl group or the like).

  具有以下式子（1）所代表的化合物残基（其中Ar代表芳基或一价杂环基）和以下式子（2）所代表的化合物残基的聚合物化合物：其中Z1到Z3中的一个成员表示—N═，其余两个残基各代表—C（R′）═。Z4和Z5分别表示—C（R′）═。Z6到Z8中的一个成员表示—N═，其余两个残基各代表—C（R′）═。Z9和Z10分别表示—C（R′）═。R′表示氢原子、烷基或类似物。
• ORGANIC MATERIALS FOR OLEDS
  申请人：UNIVERSAL DISPLAY CORPORATION

  公开号：US20150207082A1

  公开（公告）日：2015-07-23

  A novel compound based on aza- and diazodibenzofurans; aza- and diaza dibenzothiophenes, such as benzothieno- and benzofuropyrimidines as well as benzothieno- and benzofuropyrazines useful for electron-transporting host material in green, red, yellow, and white phosphorescent emitting devices is disclosed.

  本发明揭示了一种基于氮杂二苯并呋喃和氮杂二苯并噻吩的新化合物；例如苯并噻吩和苯并呋吡啶以及苯并噻吩和苯并呋吡嗪，这些化合物可用作绿色、红色、黄色和白色磷光发射器件中的电子传输宿主材料。
• ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES
  申请人：Universal Display Corporation

  公开号：US20150243893A1

  公开（公告）日：2015-08-27

  The present disclosure provides novel compounds based on azadibenzothiophenes, azadibenzofurans and azadibenzoselenophenes with at least two nitrogen atoms in the aza rings. The compounds can be used in green, red, yellow and white emitting devices as electron-transporting hosts.

  本公开提供基于氮杂二苯并噻吩，氮杂二苯并呋喃和氮杂二苯并硒杂苯的新化合物，其中至少有两个氮原子在杂环中。这些化合物可以用作绿色、红色、黄色和白色发光器件中的电子传输主体。
• HETEROARYL COMPOUNDS AS IRAK INHIBITORS AND USES THEREOF
  申请人：Merck Patent GmbH

  公开号：US20160145252A1

  公开（公告）日：2016-05-26

  The present invention relates to compounds of Formula I and pharmaceutically acceptable compositions thereof, useful as IRAK inhibitors.

  本发明涉及公式I化合物及其药学上可接受的组合物，作为IRAK抑制剂有用。