N,N-bis(carboxymethyl)aspartic acid | 66294-88-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N,N-bis(carboxymethyl)aspartic acid
• 英文别名: BCAA；aspartic acid-N,N-diacetic acid；N,N'-Bis-(carboxymethyl)-asparaginsaeure；N,N-Bis-(carboxymethyl)-asparaginsaeure；Bis(carboxymethyl)aminosuccinic acid；2-[bis(carboxymethyl)amino]butanedioic acid
• CAS: 66294-88-0
• 化学式: C₈H₁₁NO₈
• 分子量: 249.177
• InChiKey: DCCWEYXHEXDZQW-UHFFFAOYSA-N

物化性质

• 沸点：
  526.2±50.0 °C(Predicted)
• 密度：
  1.698±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -3.7
• 重原子数：
  17
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  152
• 氢给体数：
  4
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  顺丁烯二酸 、 亚氨基二乙酸 在 sodium hydroxide 作用下， 生成 N,N-bis(carboxymethyl)aspartic acid
  参考文献：
  名称：

  Gorelov,I.P. et al., Journal of general chemistry of the USSR, 1979, vol. 49, p. 573 - 576

  摘要：

  DOI：

文献信息

• NOVEL SYNTHESIS AND APPLICATIONS OF AMINO CARBOXYLATES
  申请人：Miralles Altony J.

  公开号：US20090264677A1

  公开（公告）日：2009-10-22

  A method of synthesizing carboxylated amines is disclosed. The method comprises reacting a mixture of a potassium salt of either a primary or secondary amine with a potassium salt of a halogenated carboxylic acid wherein the halogenated carboxylic acid is selected from the group consisting of brominated, chlorinated, or iodinated carboxylic acid in the presence of potassium hydroxide, and optionally in heating the reacting mixture; precipitating the potassium salt by optionally chilling the mixture and discarding the precipitate; purifying the carboxylate amine potassium salt from the liquid phase using water soluble alcohol and optionally adding formic acid to obtain the free aminocarboxylic acid and potassium formate. In a preferred embodiment, the halogenated carboxylic acid is chloroacetic acid.

  揭示了一种合成羧化胺的方法。该方法包括将一种一次或二次胺的钾盐与一种卤代羧酸的钾盐混合物反应，其中所述的卤代羧酸选自溴化、氯化或碘化羧酸，同时存在氢氧化钾，并且可选择性地加热反应混合物；通过可选择性地冷却混合物并丢弃沉淀来沉淀出钾盐；使用水溶性醇从液相中纯化羧酸胺钾盐，并可选择性地添加甲酸以获得游离氨基羧酸和甲酸钾。在一种首选实施例中，卤代羧酸是氯乙酸。
• Body-care and household products and compositions comprising specific sulfur-containing compounds
  申请人：Lupia Joseph A.

  公开号：US20090092561A1

  公开（公告）日：2009-04-09

  Disclosed are stabilized body care products, household products, textiles and fabrics which comprise specific sulfur containing compounds. Dyed products and articles are effectively stabilized against color degradation. The products are for example skin-care products, hair-care products, dentifrices, cosmetics, laundry detergents and fabric softeners, non-detergent based fabric care products, household cleaners and textile-care products.

  本发明涉及一种含有特定含硫化合物的稳定化身体护理产品、家居用品、纺织品和织物。染色产品和物品能够有效地稳定其颜色，这些产品例如皮肤护理产品、头发护理产品、牙膏、化妆品、洗衣液和柔顺剂、非洗涤剂基础的织物护理产品、家用清洁剂和纺织品护理产品。
• Inflammation Inhibitor Comprising Zinc Salt of Acylamino Acid
  申请人：Iwasaki Keiji

  公开号：US20070099888A1

  公开（公告）日：2007-05-03

  An inflammation inhibitor for the skin is provided containing a zinc salt of an acylamino acid and further, a cosmetic containing the inflammation inhibitor.

  提供了一种皮肤炎症抑制剂，其包含一种酰胺酸锌盐，此外还包括一种含有该炎症抑制剂的化妆品。
• Personal care compositions comprising certain dye-polymer complexes
  申请人：Song Zhiqiang

  公开号：US20090060849A1

  公开（公告）日：2009-03-05

  The present invention relates to personal care compositions comprising certain dye-polymer complexes. Additionally, methods for coloration of personal care compositions using said dye-polymer complexes are disclosed.

  本发明涉及含有某些染料-聚合物复合物的个人护理组合物。此外，还公开了使用所述染料-聚合物复合物对个人护理组合物进行着色的方法。
• POWDERY DETERGENT COMPOSITION
  申请人：Kao Corporation

  公开号：EP0999264A1

  公开（公告）日：2000-05-10

  A powdery detergent composition having a high detergency and an excellent storage stability (caking resistance), and comprising (a) a chelating agent composed of a compound having an average degree of neutralization in a molecule of 20 to 70%, a molecular weight of 600 or less, the number of carboxyl groups contained in one molecule of 3 to 5, and a constant of a chelating stability with Ca2+ of 6 to 13, (b) an alkali agent composed of a compound a 0.1% by weight aqueous solution or dispersion of wich has the maximum pH of 10 or more at 20°C, at least 5 ml of a 0.1 N HCl aqueous solution being required to adjust 1 liter of the aqueous solution or the dispersion to pH 9, and (c) a surfactant at specific ratios, respectively.

  一种粉状洗涤剂组合物，具有很高的去污力和极好的贮存稳定性（抗结块性），它包括(a)一种螯合剂，由一种化合物组成，该化合物分子中的平均中和度为 20-70%，分子量为 600 或更小，一个分子中所含的羧基数为 3-5，与 Ca2+ 的螯合稳定性常数为 6-13；(b)一种碱剂，由一种化合物组成，该化合物的 0.1%(重量)的化合物组成，其水溶液或分散液在20℃时的最大pH值为10或以上，至少需要5毫升0.1N盐酸水溶液才能将1升水溶液或分散液调节到pH值为9，以及(c)分别按特定比例配制的表面活性剂。