N-acetyl-bis(pyrimid-2-yl)aminopalladium(II)dichloride | 401572-43-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: N-acetyl-bis(pyrimid-2-yl)aminopalladium(II)dichloride
• 英文别名: dichloropalladium;N,N-di(pyrimidin-2-yl)acetamide
• CAS: 401572-43-8
• 化学式: C₁₀H₉Cl₂N₅OPd
• 分子量: 392.54
• InChiKey: DQVZWNFQKLOBSU-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  2.33
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  71.9
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  dihydrogen tetrachloropalladate(II) 、 N-acetyl-N,N-bis(pyrimid-2-yl)amide 以 甲醇 、 水 为溶剂， 以80%的产率得到N-acetyl-bis(pyrimid-2-yl)aminopalladium(II)dichloride
  参考文献：
  名称：

  Bis(pyrimidine)-based palladium catalysts: synthesis, X-ray structure and applications in Heck–, Suzuki–, Sonogashira–Hagihara couplings and amination reactions

  摘要：

  The synthesis of N,N-bis(pyrimid-2-yl)amine (1), N-acetyl-N,N-bis(pyrimid-2-yl)amide (2), N-norborn-2-ene-5-ylbis(pyrimid-2-yl)carbamide (4) is described. The Pd-complex N-acetyl-N,N-bis(pyrimid-2-yl)amine palladium dichloride (3) has been prepared from compound 2 and its X-ray structure has been determined. A polymer supported catalytic system (6) was prepared via ring-opening metathesis copolymerization of 4 with 1,4,4a,5,8,8a-hexahydro-1,4,5,8-exo-endo-dimethanonaphthalene (HDMN-6) and subsequent loading with PdCl2. Both the homogeneous and heterogeneous catalysts 3 and 6 were active in Heck-, Suzuki-, Sonogashira-Hagihara-type couplings and amination reactions using aryl iodides, bromides and chlorides. (C) 2001 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0022-328x(01)01083-x

文献信息

• Bis(pyrimidine)-based palladium catalysts: synthesis, X-ray structure and applications in Heck–, Suzuki–, Sonogashira–Hagihara couplings and amination reactions
  作者：Michael R. Buchmeiser、Thomas Schareina、Rhett Kempe、Klaus Wurst

  DOI：10.1016/s0022-328x(01)01083-x

  日期：2001.9

  The synthesis of N,N-bis(pyrimid-2-yl)amine (1), N-acetyl-N,N-bis(pyrimid-2-yl)amide (2), N-norborn-2-ene-5-ylbis(pyrimid-2-yl)carbamide (4) is described. The Pd-complex N-acetyl-N,N-bis(pyrimid-2-yl)amine palladium dichloride (3) has been prepared from compound 2 and its X-ray structure has been determined. A polymer supported catalytic system (6) was prepared via ring-opening metathesis copolymerization of 4 with 1,4,4a,5,8,8a-hexahydro-1,4,5,8-exo-endo-dimethanonaphthalene (HDMN-6) and subsequent loading with PdCl2. Both the homogeneous and heterogeneous catalysts 3 and 6 were active in Heck-, Suzuki-, Sonogashira-Hagihara-type couplings and amination reactions using aryl iodides, bromides and chlorides. (C) 2001 Elsevier Science B.V. All rights reserved.