1-phenyl-1-benzyloxypropane | 23512-89-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-phenyl-1-benzyloxypropane
• 英文别名: benzyl α-ethylbenzyl ether；O-benzyl 1-phenylpropyl ether；1-Phenylmethoxypropylbenzene；1-phenylmethoxypropylbenzene
• CAS: 23512-89-2
• 化学式: C₁₆H₁₈O
• 分子量: 226.318
• InChiKey: DYANXVRMGBPLKV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  17
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-phenyl-1-benzyloxypropane 在 Oxone 、 potassium bromide 作用下， 以 乙腈 为溶剂， 反应 24.5h， 以93%的产率得到苯丙酮
  参考文献：
  名称：

  Oxidative Debenzylation of N-Benzyl Amides and O-Benzyl Ethers Using Alkali Metal Bromide

  摘要：

  The oxidative debenzylation of N-benzyl amides and O-benzyl ethers was promoted with high efficiency by a bromo radical formed through the oxidation of bromide from alkali metal bromide under mild conditions. This reaction provided the corresponding amides from N-benzyl amides and carbonyl compounds from O-benzyl ethers in high yields.

  DOI：

  10.1021/ol501703y
• 作为产物：
  描述：

  氧化苯乙烯 、 苯甲醇 在 GaCl₃ supported on cross-linked polyvinylpyrrolidone 作用下， 反应 0.17h， 以90%的产率得到1-phenyl-1-benzyloxypropane
  参考文献：
  名称：

  使用催化量的 GaCl3/聚乙烯吡咯烷酮实现环氧化物与醇和叠氮化钠的高效区域选择性开环

  摘要：

  /PVP）。该催化剂用于在室温无溶剂条件下，由各种醇对环氧化物进行高效的区域选择性开环反应。在我们的程序中，这种非均相催化剂在中性和温和的反应条件下使用，以提供高产率的 β-烷氧基醇。此外，在 GaCl 存在下，通过 MeOH 中的叠氮化钠实现环氧化物向 β-叠氮醇的区域选择性转化

  DOI：

  10.5012/bkcs.2013.34.6.1741

文献信息

• Catalytic dehydrogenative dual functionalization of ethers: dealkylation–oxidation–bromination accompanied by C–O bond cleavage via aerobic oxidation of bromide
  作者：Katsuhiko Moriyama、Tsukasa Hamada、Yu Nakamura、Hideo Togo

  DOI：10.1039/c7cc02166f

  日期：——

  A catalytic dehydrogenative dual functionalization (DDF) of ethers via oxidation, dealkylation, and α-bromination by the aerobic oxidation of bromide was developed to obtain the corresponding α-bromo ketones in high yields. In particular, the reaction of substituted tetrahydrofurans as cyclic ethers provided 3,3-dibromo tetrahydrofuran-2-ols in high yields selectively through the double α-bromination

  通过溴的需氧氧化，通过氧化，脱烷基和α-溴化反应，开发了醚的催化脱氢双官能化（DDF），以高收率获得了相应的α-溴代酮。特别地，取代的四氢呋喃作为环醚的反应通过双α-溴化选择性地以高收率提供了3,3-二溴四氢呋喃-2-醇。
• B(C₆F₅)₃ catalyzed direct nucleophilic substitution of benzylic alcohols: an effective method of constructing C–O, C–S and C–C bonds from benzylic alcohols
  作者：Shan-Shui Meng、Qian Wang、Gong-Bin Huang、Li-Rong Lin、Jun-Ling Zhao、Albert S. C. Chan

  DOI：10.1039/c8ra05811c

  日期：——

  An efficient and general method of nucleophilic substitution of benzylic alcohols catalyzed by non-metallic Lewis acid B(C6F5)3 was developed. The reaction could be carried out under mild conditions and more than 35 examples of ethers, thioethers and triarylmethanes were constructed in high yields. Some bioactive organic molecules were synthesized directly using the methods.

  开发了一种由非金属路易斯酸B(C 6 F 5 ) 3催化的苯甲醇亲核取代的高效通用方法。该反应可以在温和的条件下进行，并且以高产率构建了超过 35 个醚、硫醚和三芳基甲烷的实例。使用该方法直接合成了一些生物活性有机分子。
• Polymerizable monomer, liquid crystal composition using polymerizable monomer, and liquid crystal display device
  申请人：DIC Corporation

  公开号：US11312906B2

  公开（公告）日：2022-04-26

  A problem to be solved by the present invention is to provide a liquid crystal composition excellent in vertical alignment and compatibility and to provide a liquid crystal display device produced using the same. The problem is solved by a liquid crystal composition containing one or two or more kinds of self-aligning polymerizable monomers and one or two or more kinds of polymerizable monomers (or polymerizable compounds) having a specific chemical structure, and a liquid crystal display device produced using the same, specifically a liquid crystal composition containing a polymerizable monomer represented by General Formula (I) and a spontaneously aligning monomer which has a chemical structure different from that of the polymerizable monomer represented by General Formula (I), and has a polar group, and a liquid crystal display device containing the same.

  本发明要解决的一个问题是提供一种垂直配向性和兼容性极佳的液晶组合物，并提供一种用其生产的液晶显示装置。本发明通过以下方法解决了这一问题：一种液晶组合物，其中含有一种或两种或两种以上的自对准可聚合单体和一种或两种或两种以上的具有特定化学结构的可聚合单体（或可聚合化合物）；一种使用该液晶组合物生产的液晶显示装置；特别是一种液晶组合物，其中含有通式(I)表示的可聚合单体和一种化学结构不同于通式(I)表示的可聚合单体且具有极性基团的自发对准单体；一种使用该液晶组合物生产的液晶显示装置。
• Direct, Iridium-Catalyzed Enantioselective and Regioselective Allylic Etherification with Aliphatic Alcohols
  作者：Satoshi Ueno、John F. Hartwig

  DOI：10.1002/anie.200705267

  日期：2008.2.22
• POLYMERIZABLE MONOMER, LIQUID CRYSTAL COMPOSITION USING POLYMERIZABLE MONOMER, AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：DIC Corporation

  公开号：US20200224098A1

  公开（公告）日：2020-07-16

  A problem to be solved by the present invention is to provide a liquid crystal composition excellent in vertical alignment and compatibility and to provide a liquid crystal display device produced using the same. The problem is solved by a liquid crystal composition containing one or two or more kinds of self-aligning polymerizable monomers and one or two or more kinds of polymerizable monomers (or polymerizable compounds) having a specific chemical structure, and a liquid crystal display device produced using the same, specifically a liquid crystal composition containing a polymerizable monomer represented by General Formula (I) and a spontaneously aligning monomer which has a chemical structure different from that of the polymerizable monomer represented by General Formula (I), and has a polar group, and a liquid crystal display device containing the same.