1,5-dihydroxy-2-methyl-6-O-β-rutinosyl-9,10-anthracenedione | 1400-38-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 1,5-dihydroxy-2-methyl-6-O-β-rutinosyl-9,10-anthracenedione
• 英文别名: 1,5-dihydroxy-2-methyl-6-(O⁶-α-L-rhamnopyranosyl-β-D-glucopyranosyloxy)-anthraquinone；1,5-Dihydroxy-2-methyl-6-(O⁶-α-L-rhamnopyranosyl-β-D-glucopyranosyloxy)-anthrachinon；1,5-dihydroxy-2-methyl-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxyanthracene-9,10-dione
• CAS: 1400-38-0
• 化学式: C₂₇H₃₀O₁₄
• 分子量: 578.527
• InChiKey: RRFXDKLEKUXSPN-HBAGQWHWSA-N

物化性质

• 沸点：
  898.4±65.0 °C(Predicted)
• 密度：
  1.71±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  41
• 可旋转键数：
  5
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  233
• 氢给体数：
  8
• 氢受体数：
  14

反应信息

• 作为反应物：
  描述：

  乙酸酐 、 1,5-dihydroxy-2-methyl-6-O-β-rutinosyl-9,10-anthracenedione 以 吡啶 为溶剂， 生成 1,5-di-O-acetyl-2-methyl-6-O-(hexa-O-acetyl-β-rutinosyl)-9,10-anthracenedione
  参考文献：
  名称：

  吗啉酮 6-O-primeveroside 和 6-O-rutinoside 的合成及结构证明

  摘要：

  摘要 合成了天然存在的 1,5-二羟基-2-甲基-6-O-β-p​​rimeverosyl-和 6-O-β-rutinosyl-anthraquinones 并确定了它们的结构。

  DOI：

  10.1016/0031-9422(80)85026-6
• 作为产物：
  描述：

  1,5,6-三羟基-2-甲基-蒽-9,10-二酮 在 calcium sulfate 、 sodium methylate 、 silver carbonate 作用下， 以 吡啶 、 甲醇 为溶剂， 反应 27.0h， 生成 1,5-dihydroxy-2-methyl-6-O-β-rutinosyl-9,10-anthracenedione
  参考文献：
  名称：

  吗啉酮 6-O-primeveroside 和 6-O-rutinoside 的合成及结构证明

  摘要：

  摘要 合成了天然存在的 1,5-二羟基-2-甲基-6-O-β-p​​rimeverosyl-和 6-O-β-rutinosyl-anthraquinones 并确定了它们的结构。

  DOI：

  10.1016/0031-9422(80)85026-6

文献信息

• Lifeforce liquid supplement
  申请人：Leitman Lorn

  公开号：US20110189319A1

  公开（公告）日：2011-08-04

  Two very important factors in human life—which play vital roles in promoting well being—includes returning the body to homeostasis and giving boost to body called lifeforce to get overall health free from diseases, i.e., its optimal balanced functioning ability. When the body is at homeostasis, there is no place for disease. It is only when the body is out of balance (something is deficient, in excess or stagnating) that pain, illness or disease can occur. The application described is based on returning the body to homeostasis (removing the problem and balancing the body) by providing lifeforce and not on dealing with the symptom (e.g., pain, vitamin deficiency). Imbalance results in various diseases and adverse health conditions (starting from aging to diabetes and cancers). This wonderful composition will interact with the body in a way that allows it to boost lifeforce and reach homeostasis no matter which direction it was. In this combination, in the form of liquid, all the 14 ingredients ( Lepidium meyenii (Maca), Croton planstigma (Dragon's blood) tree sap, Uncaria tomentosa (Cat's Claw), Morinda citrifolia (Noni fruit) 4:1 PE, Lutein, Lycopene 5%, Flaxseed Oil (Omega-3-Fatty Acids), Vinpocetine, Phosphatidyl Serine 50%, Korean Ginseng 80%, Bacopa monnieri (Bacopin), CDP Choline (Cognizing), Guaranine (Guarana Seed PE 12%), Yerba Mate Ext. 8%) work as mixture for returning the body to homeostasis and give it lifeforce.

  人类生活中两个非常重要的因素，对促进健康起着至关重要的作用，包括将身体恢复到稳态并提升被称为生命力的身体以获得健康，即其最佳平衡功能能力。当身体处于稳态时，疾病就无处容身。只有当身体失衡（某种物质缺乏、过量或停滞）时，疼痛、疾病或疾病才会发生。所描述的应用是基于将身体恢复到稳态（消除问题并平衡身体）并提供生命力，而不是处理症状（例如疼痛、维生素缺乏）。失衡会导致各种疾病和不良健康状况（从衰老到糖尿病和癌症）。这种神奇的组合将与身体互动，以一种方式让它增强生命力并达到稳态，无论它朝哪个方向。在这种液体形式的组合中，所有14种成分（Lepidium meyenii（玛卡）、Croton planstigma（龙血）树汁、Uncaria tomentosa（猫爪）、Morinda citrifolia（诺尼果）4：1提取物、叶黄素、番茄红素5%、亚麻籽油（Omega-3脂肪酸）、Vinpocetine、磷脂酰丝氨酸50%、韩国人参80%、Bacopa monnieri（Bacopin）、CDP胆碱（认知）、瓜拉宁（瓜拉纳籽提取物12%）、南美洲亚麻灌木提取物8%）作为混合物，用于将身体恢复到稳态并赋予生命力。
• [EN] ANTIMICROBIAL COMPOSITIONS AND USES THEREOF<br/>[FR] COMPOSITIONS ANTIMICROBIENNES ET LEURS UTILISATIONS
  申请人：NOVUS INT INC

  公开号：WO2017004161A1

  公开（公告）日：2017-01-05

  Antimicrobial compositions comprising sulfur- or selenium-containing, fatty-acylated alpha-hydroxy acid compounds and methods of using said compounds or compositions to inhibit microbial growth.

  含有硫或硒的脂肪酰化α-羟基酸化合物的抗微生物组合物，以及使用这些化合物或组合物抑制微生物生长的方法。
• HETEROATOM CONTAINING CYCLIC DIMERS
  申请人：Novus International Inc.

  公开号：US20130209392A1

  公开（公告）日：2013-08-15

  The present invention provides cyclic dimers of alpha acids and polymers derived therefrom. Also provided are processes for preparing and methods of using the cyclic dimers and the polymers derived from the cyclic dimers.

  本发明提供了α酸的环状二聚体及其衍生物聚合物。还提供了制备环状二聚体及其衍生物聚合物的方法和使用方法。
• Compositions and methods for the treatment of inflammatory diseases
  申请人：——

  公开号：US20030139353A1

  公开（公告）日：2003-07-24

  Topoisomerase inhibitors are useful for the treatment of inflammatory disorders including arthritis, restenosis, surgical adhesions and other diseases. Controlled release polymeric formulations to topoisomerase inhibitors are particularly suitable for this use.

  拓扑异构酶抑制剂对于治疗炎症性疾病包括关节炎、再狭窄、手术粘连和其他疾病非常有用。控制释放聚合物制剂对拓扑异构酶抑制剂特别适用于此用途。
• SUPERCRITICAL FLUID MICROENCAPSULATION OF DYE INTO LATEX FOR IMPROVED EMULSION AGGREGATION TONER
  申请人：Sweeney Maura A.

  公开号：US20110053076A1

  公开（公告）日：2011-03-03

  The present disclosure provides methods for incorporating a dye into latex particles via a supercritical fluid microencapsulation technique, in order to achieve improved dispersion of a colorant in the latex and an increase in color gamut.

  本公开提供了一种使用超临界流体微囊化技术将染料纳入乳胶颗粒中的方法，以实现染料在乳胶中更好的分散和色域的增加。