1,1-dichloro-trans-2,3-diphenylcyclopropane

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 1,1-dichloro-trans-2,3-diphenylcyclopropane
• 英文别名: 2,2-dichloro-1,3-diphenylcyclopropane；trans-1,1-dichloro-2,3-diphenylcyclopropane；[(1R,3R)-2,2-dichloro-3-phenylcyclopropyl]benzene
• 化学式: C₁₅H₁₂Cl₂
• 分子量: 263.166
• InChiKey: DJDNTZDWSNETAS-KBPBESRZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1,1-dichloro-trans-2,3-diphenylcyclopropane 在 sodium iodide 作用下， 以 丙酮 为溶剂， 生成
  参考文献：
  名称：

  Luckenbach,R.; Mueller,N., Zeitschrift fur Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1979, vol. 34, p. 464 - 480

  摘要：

  DOI：
• 作为产物：
  描述：

  四氯化碳 、 顺式-二苯乙烯 在 四氯化钛 、 magnesium 作用下， 以 四氢呋喃 、 1,2-二氯乙烷 为溶剂， 反应 1.0h， 以83%的产率得到1,1-dichloro-trans-2,3-diphenylcyclopropane
  参考文献：
  名称：

  Novel Ambiphilic Dichlorocarbenoid Equivalent in Alkene Cyclopropanation and Carbonyl Olefination

  摘要：

  The Ti-Mg-dichloromethylene complexes derived from the oxidative addition of CCl4 to the Mg-TiCl4 bimetallic species serve as a novel class of ambiphilic dichlorocarbenoid equivalents. Not only is Ti-Mg-dichlorocarbenoid highly selective but also it seems highly reactive in both alkene cyclopropanations and carbonyl dichloromethylenations.

  DOI：

  10.1021/jo052610t

文献信息

• Halomethyl-Metal Compounds. II. The Preparation of gem-Dihalocyclopropanes by the Reaction of Phenyl(trihalomethyl)mercury Compounds with Olefins¹
  作者：Dietmar Seyferth、James M. Burlitch、Richard J. Minasz、Jeffrey Yick-Pui Mui、Harry D. Simmons、Arno J. H. Treiber、Susan R. Dowd

  DOI：10.1021/ja00947a009

  日期：1965.10
• Montanari, Fernando; Penso, Michele; Fortuna, Giorgio della, Gazzetta Chimica Italiana, 1985, vol. 115, # 8, p. 427 - 432
  作者：Montanari, Fernando、Penso, Michele、Fortuna, Giorgio della、Re, Alberto

  DOI：——

  日期：——
• Synthesis of bridging vinylideneiron dimers using 1,1-dichlorocyclopropanes. Cyclopropenes as intermediates
  作者：David F. Marten、Eckehard V. Dehmlow、David J. Hanlon、M. Bilayet Hossain、Dick Van der Helm

  DOI：10.1021/ja00406a045

  日期：1981.8
• Nitration of 2-Aryl-1,1-dihalocyclopropanes Containing Methyl or Phenyl Group
  作者：Lee-Huey Lin、Shaw-Tao Lin、Hucy-Ju Yang

  DOI：10.1002/jccs.199800032

  日期：1998.2

  AbstractGem‐dihalocyclopropanes bearing a phenyl group and an additional group were nitrated by using nitric acid in a sulfuric acid matrix. The products from the nitration of aryl rings are major. The presence of a methyl group on the C(2) position of the cyclopropane ring leads to the isoxazoline from nitration at the C(1)‐position instead of that from nitration at the C(2)‐position.
• Synthesis of 2,3-Diphenylacrolein Acetals
  作者：G. N. Sakhabutdinova、G. Z. Raskilʼdina、S. S. Zlotskii

  DOI：10.1134/s1070363220090248

  日期：2020.9

  Linear acetals have been synthesized by decompositiontrans- andcis-1,1-dichloro-2,3-diphenylcyclopropanes in the presence of aliphatic alcohols (ethanol and butan-1-ol). The reactivities of puretrans- andcis-stilbenes and styrene toward dichlorocarbene have been compared. The structure of the isolated compounds was determined by NMR and GC/MS.