ethyl 4,6,6,6-tetrachlorohexanoate | 13038-10-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: ethyl 4,6,6,6-tetrachlorohexanoate
• 英文别名: 4,6,6,6-Tetrachlor-hexansaeure-aethylester；Hexanoic acid, 4,6,6,6-tetrachloro-, ethyl ester
• CAS: 13038-10-3
• 化学式: C₈H₁₂Cl₄O₂
• 分子量: 281.994
• InChiKey: HGBKSXQEXIUOAR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  四氯化碳 、 4-戊烯酸乙酯 在 过氧化苯甲酰 作用下， 生成 ethyl 4,6,6,6-tetrachlorohexanoate
  参考文献：
  名称：

  Dolezal,S., Collection of Czechoslovak Chemical Communications, 1966, vol. 31, p. 3765 - 3774

  摘要：

  DOI：

文献信息

• Addition of Trichloromethyl Radicals to Alkenes: The Use of Phosphites as Hydrogen-Atom Donors in Intermolecular Radical Reactions
  作者：Jenny M. Barks、Bruce C. Gilbert、Andrew F. Parsons、Bala Upeandran

  DOI：10.1055/s-2001-18086

  日期：——

  Addition of trichloromethyl radicals (generated from BrCCl3 or CCl4) to a variety of alkenes in the presence of hydrogen-atom donors has been explored. The use of phosphites as hydrogen-atom donors was shown to provide a mild, novel and technically clean approach to trichloroalkanes.

  在氢原子供体存在下，将三氯甲基自由基（由BrCCl3或CCl4生成）加入到各种烯烃中的研究已经展开。使用膦作为氢原子供体被证明为制备三氯烷基化合物提供了一种温和、新颖且技术上清洁的方法。
• Palladium-catalyzed addition reaction of olefins, carbon tetrachloride and carbon monoxide in alcohols to give 2-alkyl-4,4,4-trichlorobutanoates
  作者：Jiro Tsuji、Koji Sato、Hideo Nagashima

  DOI：10.1016/s0040-4020(01)96745-6

  日期：1985.1

  Pd(OAc)2 combined with PPh3 is a good catalyst for the addition reaction of CCl4 and CO to olefins in ethanol to afford ethyl 2-alkyl-4,4,4-trichlorobutanoates. The esters were obtained in satisfactory yields when the reaction was carried out at 50° in the presence of K2CO3 under CO pressure.

  Pd（OAc）2与PPh 3结合是将CCl 4和CO加成乙醇中的烯烃，得到2-烷基-4,4,4-三氯丁酸乙酯的良好催化剂。当反应在50℃下在K 2 CO 3存在下在CO压力下进行时，以令人满意的收率获得酯。
• Process for preparing high cis 3-(2,2,2-trichloroethyl)-2,2-dimethylcyclopropane-1-carboxylates
  申请人：FMC Corporation

  公开号：EP0003683A2

  公开（公告）日：1979-08-22

  A process is described whereby esters of 3-(2,2,2-trichloroethyl) - 2,2- dimethylcyclopropane - 1 - carboxylic acid are prepared predominantly in their cis isomer form. The process comprises treating a 4,6,6,6-tetrachloro-3,3-dimethylhexanoate with an alkali metal tert-alkoxide under controlled conditions of temperature in the presence of a defined solvent-cosolvent mixture. The products of the process are intermediates in the production of pyrethroid insecticides.

  描述了一种主要以顺式异构体形式制备 3-(2,2,2-三氯乙基)-2,2-二甲基环丙烷-1-羧酸酯的工艺。 该工艺包括在确定的溶剂-共溶剂混合物存在下，在受控温度条件下用碱金属叔烷氧化物处理 4,6,6,6-四氯-3,3-二甲基己酸酯。 该工艺的产物是生产拟除虫菊酯杀虫剂的中间体。
• Activation of polyhaloalkanes by palladium catalyst. Preparation of γ-trichloro esters by coaddition reaction of carbon tetrachloride and carbon monoxide to olefins
  作者：Jiro Tsuji、Koji Sato、Hideo Nagashima

  DOI：10.1016/s0040-4039(00)86976-2

  日期：1982.1
• TSUJI, JIRO;SATO, KOJI;NAGASHIMA, HIDEO, TETRAHEDRON LETT., 1982, 23, N 8, 893-896
  作者：TSUJI, JIRO、SATO, KOJI、NAGASHIMA, HIDEO

  DOI：——

  日期：——