N-(3-(diethylamino)propyl)-D-gluconamide | 55728-06-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: N-(3-(diethylamino)propyl)-D-gluconamide
• 英文别名: N-[3-(Diethylamino)propyl]-D-gluconamide；(2R,3S,4R,5R)-N-[3-(diethylamino)propyl]-2,3,4,5,6-pentahydroxyhexanamide
• CAS: 55728-06-8
• 化学式: C₁₃H₂₈N₂O₆
• 分子量: 308.375
• InChiKey: GDMSHMZYJKROID-WISYIIOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.5
• 重原子数：
  21
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  134
• 氢给体数：
  6
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  3-二乙胺基丙胺 、 葡萄糖酸内酯 以 甲醇 为溶剂， 反应 6.0h， 以77%的产率得到N-(3-(diethylamino)propyl)-D-gluconamide
  参考文献：
  名称：

  Synthesis and evaluation of d-gluconamides as green mineral scales

  摘要：

  A series of 13 D-gluconamides were synthesized in moderate to good yields and evaluated as green scale inhibitors. The crystal structures of two compounds were determined by X-ray crystallography. The compounds 6c and 6d showed a reasonable inhibition of BaSO4 precipitation from aqueous solution (47% and 51%, respectively) that indicated the potential for these derivatives of delta-gluconolactone. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2012.01.027

文献信息

• US4038294A
  申请人：——

  公开号：US4038294A

  公开（公告）日：1977-07-26
• Synthesis and evaluation of d-gluconamides as green mineral scales
  作者：Marcelo I.P. Reis、Aline D. Gonçalves、Fernando de C. da Silva、Alessandro K. Jordão、Ricardo J. Alves、Saulo Fernandes de Andrade、Jackson A.L.C. Resende、Anderson A. Rocha、Vitor F. Ferreira

  DOI：10.1016/j.carres.2012.01.027

  日期：2012.5

  A series of 13 D-gluconamides were synthesized in moderate to good yields and evaluated as green scale inhibitors. The crystal structures of two compounds were determined by X-ray crystallography. The compounds 6c and 6d showed a reasonable inhibition of BaSO4 precipitation from aqueous solution (47% and 51%, respectively) that indicated the potential for these derivatives of delta-gluconolactone. (C) 2012 Elsevier Ltd. All rights reserved.