| 63556-21-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• CAS: 63556-21-8
• 化学式: C20H40N2NaO4
• 分子量: 395.5
• InChiKey: LCXHPZSXDCUHRT-UHFFFAOYSA-N

物化性质

• LogP：
  5.333 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  27
• 可旋转键数：
  19
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  89.9
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• EXTERNAL PREPARATION FOR SKIN AND CLEANSING AGENT FOR SKIN
  申请人：SHISEIDO COMPANY, LTD.

  公开号：EP2082729A1

  公开（公告）日：2009-07-29

  The present invention was made in view of the above-described circumstances, and an object of the invention is to provide an external skin preparation having a rough skin improving effect, excellent in texture in use, especially excellent in smoothness, free of sticky feeling, and excellent in stability. Another object is to provide a skin cleanser excellent especially in usability and a cosmetic removing effect. That is, the external skin preparation of the present invention is characterized by comprising a block-type alkylene oxide derivative represented by the below-described formula (I).         [formula 1] Y-[O(EO)a-(AO)b-(EO)o-R]k     (I) (In the formula, Y is the residue given by removing hydroxyl groups from a polyhydric alcohol having 3 to 6 hydroxyl groups, and k is the number of hydroxyl groups of the polyhydric alcohol. EO is an oxyethylene group, AO is an oxyalkylene group having 3 to 6 carbon atoms, and they are attached in a block-type, respectively. The products, a×k, b×k, and c×k, are the average addition mole numbers of the oxyethylene group, the oxyalkylene group having 3 to 6 carbon atoms, and the oxyethylene group, respectively, and 0 ≦a×k≦ 100, 1≦b×k≦ 100, and 0≦c×k≦ 100, however, (a+c)×k>1. The percentage of all oxyethylene groups in formula (I) with respect to the sum of all oxyethylene groups and oxyalkylene groups having 3 to 6 carbon atoms in formula (I) is 10 to 80 mass %. Rs may be either identical to or different from each other, and they are hydrocarbon groups with 1 to 4 carbon atoms.) The skin cleanser of present invention is characterized by comprising 0.01 to 70 mass % of a block-type alkylene oxide derivative represented by the above-described formula (I) and 0.1 to 20 mass % of a moisturizer.

  本发明是鉴于上述情况而提出的，其目的是提供一种外用皮肤制剂，该制剂具有改善皮肤粗糙的效果，使用时质地优良，特别是光滑度优良，无粘腻感，稳定性优良。本发明的另一个目的是提供一种皮肤清洁剂，其使用性和化妆品去除效果尤为出色。 也就是说，本发明的外用护肤制剂的特点是包含由下述式（I）表示的块状环氧烷衍生物。 [式 1] Y-[O(EO)a-(AO)b-(EO)o-R]k (I) (式中：Y 为从具有 3 至 6 个羟基的多元醇中去除羟基后的残留物，k 为多元醇的羟基数。EO 是氧乙烯基，AO 是具有 3 至 6 个碳原子的氧亚烷基，它们分别以块状连接。产物 a×k、b×k 和 c×k 分别是氧乙烯基、具有 3 至 6 个碳原子的氧亚烃基和氧乙烯基的平均加和摩尔数，且 0 ≦a×k≦100、1≦b×k≦100 和 0≦c×k≦100，但 (a+c)×k>1 。式(I)中所有氧乙烯基团占式(I)中所有氧乙烯基团和具有 3 至 6 个碳原子的氧亚烃基团之和的百分比为 10 至 80 质量%。Rs既可以相互相同，也可以相互不同，它们都是具有 1 至 4 个碳原子的烃基团）。 本发明洁肤剂的特点是含有 0.01 至 70 质量％的由上述式（I）代表的块状环氧烷衍生物和 0.1 至 20 质量％的保湿剂。
• ANHYDROUS SOLID COMPOSITION COMPRISING AN ISETHIONIC ACID DERIVATIVE, A GLUTAMIC ACID DERIVATIVE, AN AMPHOTERIC SURFACTANT AND FILLERSANHYDROUS SOLID COMPOSITION COMPRISING AN ISETHIONIC ACID DERIVATIVE, A GLUTAMIC ACID DERIVATIVE, AN AMPHOTERIC SURFACTANT AND FILLERS
  申请人：L'Oréal

  公开号：EP3644948A1

  公开（公告）日：2020-05-06
• External Skin Preparation And Skin Cleanser
  申请人：Ohmori Takashi

  公开号：US20100075882A1

  公开（公告）日：2010-03-25

  The present invention was made in view of the above-described circumstances, and an object of the invention is to provide an external skin preparation having a rough skin improving effect, excellent in texture in use, especially excellent in smoothness, free of sticky feeling, and excellent in stability. Another object is to provide a skin cleanser excellent especially in usability and a cosmetic removing effect. That is, the external skin preparation of the present invention is characterized by comprising a block-type alkylene oxide derivative represented by the below-described formula (I). [formula 1] Y—[O(EO) a -(AO) b -(EO) c -R] k (I) (In the formula, Y is the residue given by removing hydroxyl groups from a polyhydric alcohol having 3 to 6 hydroxyl groups, and k is the number of hydroxyl groups of the polyhydric alcohol. EO is an oxyethylene group, AO is an oxyalkylene group having 3 to 6 carbon atoms, and they are attached in a block-type, respectively. The products, a×k, b×k, and c×k, are the average addition mole numbers of the oxyethylene group, the oxyalkylene group having 3 to 6 carbon atoms, and the oxyethylene group, respectively, and 0≦a×k≦100, 1≦b×k≦100, and 0≦c×k≦100, however, (a+c)×k>1. The percentage of all oxyethylene groups in formula (I) with respect to the sum of all oxyethylene groups and oxyalkylene groups having 3 to 6 carbon atoms in formula (I) is 10 to 80 mass %. Rs may be either identical to or different from each other, and they are hydrocarbon groups with 1 to 4 carbon atoms.) The skin cleanser of present invention is characterized by comprising 0.01 to 70 mass % of a block-type alkylene oxide derivative represented by the above-described formula (I) and 0.1 to 20 mass % of a moisturizer.
• ANHYDROUS SOLID COMPOSITION COMPRISING AN ISETHIONIC ACID DERIVATIVE, A GLUTAMIC ACID DERIVATIVE, AN AMPHOTERIC SURFACTANT AND FILLERS
  申请人：L'OREAL

  公开号：US20210137800A1

  公开（公告）日：2021-05-13

  Anhydrous solid composition comprising an isethionic acid derivative, a glutamic acid derivative, an amphoteric surfactant and fillers The subject of the present invention is a composition, preferably a cosmetic composition, in anhydrous solid form, comprising at least one anionic surfactant chosen from isethionic acid derivatives and salts thereof, at least one anionic surfactant chosen from glutamic acid derivatives and salts thereof, at least one amphoteric surfactant, and at least 20% by weight of fillers, relative to the total weight. The composition in accordance with the invention is advantageously in the form of granules, the particle size of which is homogeneous. It readily disaggregates or disintegrates, it is easy to apply to keratin materials, and it allows rapid foam initiation, when the composition is applied to said keratin materials, and also good foam quality.
• [EN] NON-AEROSOL DEVICE CONTAINING A TWO-PHASE COSMETIC COMPOSITION AND PROCESS FOR THE COSMETIC TREATMENT OF KERATIN MATERIALS<br/>[FR] DISPOSITIF NON AÉROSOL CONTENANT UNE COMPOSITION COSMÉTIQUE À DEUX PHASES ET PROCÉDÉ DE TRAITEMENT COSMÉTIQUE DES MATIÈRES KÉRATINIQUES
  申请人：OREAL

  公开号：WO2018177815A1

  公开（公告）日：2018-10-04

  The invention relates to a non-aerosol device comprising a bottle equipped with a mechanical pumping system and comprising a composition and a dispensing system which makes it possible to deliver the composition in foam form, said composition comprising an aqueous phase and an oily phase that are visually distinct and superimposed, an amphoteric surfactant and a fatty acid salt. Application to the cosmetic treatment of keratin materials by application of the composition in foam form, obtained with the non-aerosol device, to the keratin materials.