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| 1643-21-6

中文名称
——
中文别名
——
英文名称
——
英文别名
——
化学式
CAS
1643-21-6
化学式
C12H26KO3S
mdl
——
分子量
289.5
InChiKey
STNXDVQYLMLGRF-UHFFFAOYSA-N
BEILSTEIN
——
EINECS
——
  • 物化性质
  • 计算性质
  • ADMET
  • 安全信息
  • SDS
  • 制备方法与用途
  • 上下游信息
  • 反应信息
  • 文献信息
  • 表征谱图
  • 同类化合物
  • 相关功能分类
  • 相关结构分类

计算性质

  • 辛醇/水分配系数(LogP):
    3.41
  • 重原子数:
    17
  • 可旋转键数:
    11
  • 环数:
    0.0
  • sp3杂化的碳原子比例:
    1.0
  • 拓扑面积:
    62.8
  • 氢给体数:
    1
  • 氢受体数:
    3

文献信息

  • DEPROTECTION METHOD FOR TETRAZOLE COMPOUND
    申请人:API CORPORATION
    公开号:US20150239854A1
    公开(公告)日:2015-08-27
    The present invention relates to a method of deprotecting a tetrazole compound, useful as an intermediate for angiotensin II receptor blockers, and provides a novel production method of angiotensin II receptor blockers. Provided is a production method of a compound represented by the formula [3] or [4] or a salt thereof, including (i) reducing a compound represented by the formula [1] or [2] or a salt thereof in the presence of a metal catalyst and an alkaline earth metal salt, or (ii) reacting the compound with a particular amount of Brønsted acid: wherein each symbol is as defined in the present specification.
    本发明涉及一种去保护四唑化合物的方法,该方法作为血管紧张素II受体拮抗剂的中间体,并提供了一种新颖的血管紧张素II受体拮抗剂的生产方法。 提供了一种由式[3]或[4]表示的化合物或其盐的生产方法,包括(i)在金属催化剂和碱土金属盐的存在下还原式[1]或[2]表示的化合物或其盐,或(ii)将该化合物与特定量的Brønsted酸反应: 其中每个符号如本说明书中所定义。
  • POLYQUATERNARY ORGANOSILICON COMPOUNDS-CONTAINING COMPOSITION
    申请人:Ochs Christian
    公开号:US20070212326A1
    公开(公告)日:2007-09-13
    Polymers containing repeating organopolysiloxane blocks and including quaternary ammonium groups in the polymer chain exhibit good biocidal properties, while also exhibiting good washfastness, hydrophilicity, and softness.
    含有重复有机聚硅氧烷块并在聚合物链中包含季铵基团的聚合物表现出良好的杀菌性能,同时还表现出良好的耐洗性、亲水性和柔软性。
  • IN SITU SOLIDIFYING COMPLEX COACERVATES AND METHODS OF MAKING AND USING THEREOF
    申请人:UNIVERSITY OF UTAH RESEARCH FOUNDATION
    公开号:US20170157285A1
    公开(公告)日:2017-06-08
    Described herein are fluid complex coacervates that produce solid adhesives in situ. Oppositely charged polyelectrolytes were designed to form fluid adhesive complex coacervates at ionic strengths higher than the ionic strength of the application site, but an insoluble adhesive solid or gel at the application site. When the fluid, high ionic strength adhesive complex coacervates are introduced into the lower ionic strength application site, the fluid complex coacervate is converted to a an adhesive solid or gel as the salt concentration in the complex coacervate equilibrates to the application site salt concentration. In one embodiment, the fluid complex coacervates are designed to solidify in situ at physiological ionic strength and have numerous medical applications. In other aspects, the fluid complex coacervates can be used in aqueous environment for non-medical applications.
    本文描述了一种可在原位产生固体粘合剂的流体复合共沉淀物。设计了带有相反电荷的聚电解质,以形成在离子强度高于应用现场的离子强度时形成流体粘合复合共沉淀物,但在应用现场形成不溶性粘合固体或凝胶。当将流体高离子强度粘合复合共沉淀物引入较低离子强度的应用现场时,复合共沉淀物中的盐浓度与应用现场的盐浓度达到平衡时,流体复合共沉淀物转化为粘合固体或凝胶。在一种实施方式中,流体复合共沉淀物被设计为在生理离子强度下原位固化,并具有众多医疗应用。在其他方面,流体复合共沉淀物可用于非医疗应用的水环境中。
  • Aqueous polymeric dispersions and paper coating compositions
    申请人:THE DOW CHEMICAL COMPANY
    公开号:EP0019716A1
    公开(公告)日:1980-12-10
    Lightweight coated paper products with improved properties are obtained by use of coating compositions employing as the binder component certain novel polymeric dispersions which comprise (A) a major proportion on a dry basis of an alkali-insoluble polymer and (B) a minor proportion (e.g., from 0.5 to 25 weight percent on a dry basis based upon the alkali-insoluble polymer) of certain alkali-soluble polymers. Exemplary of the alkali-insoluble polymers employed are carboxylated and noncarboxylated addition polymerized synthetic polymers having a glass transition temperature of about 50° C or less. Exemplary of the alkali-soluble polymers are synthetic addition polymers comprising in polymerized form (1) about 40 to 90 weight percent of a vinyl ester of a carboxylic acid (e.g., vinyl acetate, vinyl propionate, etc.); (2) about 5 to 55 percent of the nitrile, C2-C. hydroxyalkyl ester, or C1-C8 alkyl ester of a monoethylenically unsaturated carboxylic acid; and (3) about 5 to 15 percent of a monoethylenically unsaturated carboxylic acid.
    通过使用某些新型聚合物分散体作为粘合剂成分的涂层组合物,可获得性能更好的轻质涂布纸产品,这些聚合物分散体包括(A)以干基为基准的主要比例的碱不溶性聚合物和(B)以干基为基准的次要比例(例如,以碱不溶性聚合物为基准的 0.5 至 25 重量百分比)的某些碱溶性聚合物。所使用的碱不溶性聚合物示例为羧化和非羧化加成聚合合成聚合物,其玻璃化温度约为 50 摄氏度或更低。碱溶性聚合物的范例是合成加成聚合物,其聚合形式包括 (1) 约 40 至 90 重量百分比的羧酸乙烯基酯(例如:乙酸乙烯基酯); (2) 约 40 至 90 重量百分比的羧酸乙烯基酯(例如:乙酸乙烯基酯); (3) 约 40 至 90 重量百分比的羧酸乙烯基酯(例如:乙酸乙烯基酯)、乙酸乙烯酯、丙酸乙烯酯等);(2) 约 5-55%的单乙烯基不饱和羧酸的腈基、C2-C. 羟基烷基酯或 C1-C8 烷基酯;以及 (3) 约 5-15%的单乙烯基不饱和羧酸。
  • Sequential emulsion polymerization process for structured particle latex products
    申请人:THE DOW CHEMICAL COMPANY
    公开号:EP0031964A2
    公开(公告)日:1981-07-15
    Aqueous copolymer latexes comprising colloidally dispersed, substantially spheroidal copolymer particles having a predominantly hydrophobic core portion and having a relatively hydrophilic polymeric portion which is preferentially oriented toward the outer surface as a shell portion are prepared by (a) emulsion polymerizing an initial monomer charge to form a first aqueous latex of a substantially linear, relatively hydrophilic polymer and (b) thereafter emulsion polymerizing a major proportion from about 50 to 95 parts by weight of a second and relatively more hydrophobic monomer charge in the presence of a minor proportion from about 5 to 50 parts by weight on a polymer solids basis of said first, relatively hydrophilic polymer latex.
    水性共聚物胶乳包括胶体分散的、基本上呈球形的共聚物颗粒,该颗粒具有主要疏水的核心部分和相对亲水的聚合物部分,该聚合物部分作为外壳部分优先朝向外表面,其制备方法是:(a) 乳化聚合初始单体电荷以形成基本上线性的第一种水性胶乳、(b) 之后,在所述第一种相对亲水聚合物胶乳中,以聚合物固体为基础,以约 5 至 50 重量份为次要比例,乳液聚合约 50 至 95 重量份的第二种相对更疏水的单体。
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