icosan-9-yl (Z,12R)-12-hydroxyoctadec-9-enoate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: icosan-9-yl (Z,12R)-12-hydroxyoctadec-9-enoate
• 化学式: C₃₈H₇₄O₃
• 分子量: 579.0
• InChiKey: HQRJTRSKPWEIII-OCANKYAHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  15.7
• 重原子数：
  41
• 可旋转键数：
  34
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• SKIN EXTERNAL PREPARATIONS AND COSMETICS
  申请人：Aoki Hirobumi

  公开号：US20100280111A1

  公开（公告）日：2010-11-04

  An object of the present invention is to provide skin external preparations and cosmetics which contain a branched acyl carnitine and have excellent formulation stability. A skin external preparation of the present invention includes a carnitine derivative represented by the following Formula (1) and/or a carnitine derivative salt represented by the following Formula (2), and an amphoteric surfactant. In Formula (1), R 1 and R 2 are each independently a C1-18 optionally branched, saturated or unsaturated aliphatic hydrocarbon group. In Formula (2), R 1 and R 2 are the same as in Formula (1), X − is a specific anion and Y + is a specific cation.

  本发明的一个目的是提供含有支链酰基肉碱并具有优异配方稳定性的皮肤外用制剂和化妆品。本发明的皮肤外用制剂包括以下式（1）所表示的肉碱衍生物和/或以下式（2）所表示的肉碱衍生物盐，以及一种两性表面活性剂。在式（1）中，R1和R2分别独立地是C1-18的可选支链、饱和或不饱和脂肪烃基。在式（2）中，R1和R2与式（1）中相同，X−是特定的阴离子，Y+是特定的阳离子。
• OIL-IN-WATER EMULSION COSMETIC COMPOSITION
  申请人：Dow Toray Co., Ltd.

  公开号：US20210330559A1

  公开（公告）日：2021-10-28

  An oil-in-water emulsion cosmetic composition is provided. The oil-in-water emulsion cosmetic composition comprises a carboxylic acid modified silicone (A) that has a specific chemical structure and is liquid at room temperature, an oil agent (B), and water (C). The oil-in-water emulsion cosmetic composition can provide a cosmetic film with high stability and excellent water resistance.

  提供了一种油包水乳化化妆品组合物。该油包水乳化化妆品组合物包括一种在室温下为液体的具有特定化学结构的羧酸改性硅氧烷（A）、一种油剂（B）和水（C）。该油包水乳化化妆品组合物可以提供具有高稳定性和优异耐水性的化妆膜。
• COSMETIC
  申请人：Dow Toray Co., Ltd.

  公开号：US20210244641A1

  公开（公告）日：2021-08-12

  A cosmetic composition is provided. The cosmetic composition comprises a carboxylic acid modified silicone (A) that has a specific chemical structure and is liquid at room temperature. The cosmetic composition also comprises an oil agent (B). The cosmetic composition generally provides a cosmetic film having excellent water resistance, and can be easily removed by normal soap and water.

  提供一种化妆品组合物。该化妆品组合物包括一种在室温下为液体的具有特定化学结构的羧酸修饰硅氧烷（A）。该化妆品组合物还包括一种油剂（B）。该化妆品组合物通常提供具有优异耐水性的化妆膜，并可轻松用普通肥皂和水去除。
• SKIN AGENT FOR EXTERNAL USE AND COSMETIC AGENT INCLUDING UBIQUINONE DERIVATIVE OR SALT THEREOF AND METHOD USING THE SAME
  申请人：Aoki Hirobumi

  公开号：US20100074879A1

  公开（公告）日：2010-03-25

  A skin agent for external use and a cosmetic agent are provided, by transdermal administration of which expected actions and effects of ubiquinone derivatives, salts thereof, ubiquinones and ubiquinols are effectively obtained. The skin agent for external use includes a ubiquinone derivative or a salt thereof as an active ingredient. The ubiquinone derivative is represented by the formula (1): wherein R 1 and R 2 are each a hydrogen atom or a phosphoric group, at least one of R 1 and R 2 is a phosphoric group, and n is an integer in the range of 1 to 9.

  提供了一种外用皮肤剂和化妆品剂，通过经皮给药，可以有效地获得辅酶Q衍生物、其盐、辅酶Q和辅酶QH的预期作用和效果。外用皮肤剂包括辅酶Q衍生物或其盐作为活性成分。辅酶Q衍生物由式（1）表示：其中R1和R2分别是氢原子或磷酸基团，R1和R2中至少有一个是磷酸基团，n是1到9范围内的整数。
• [EN] A SKIN CARE AND COSMETIC PREPARATION CONTAINING AN INOSITOL DERIVATIVE<br/>[FR] UNE PRÉPARATION COSMÉTIQUE ET DERMATOLOGIQUE CONTENANT UN DÉRIVÉ INOSITOL
  申请人：SHOWA DENKO KK

  公开号：WO2005092285A1

  公开（公告）日：2005-10-06

  The present invention discloses a preparation to be applied externally to the skin which contains an inositol derivative in which an inositol and a saccharide are combined. The invention aims to provide an external skin preparation that can be spread over skin without causing a granular feeling and has excellent moisturising effects and of keeping the skin healthy.

  本发明公开了一种用于外部涂抹于皮肤的制剂，其中包含一种肌醇衍生物，该肌醇衍生物中结合了肌醇和一种糖类。该发明旨在提供一种外用皮肤制剂，可以在皮肤上涂抹而不会产生颗粒感，具有优秀的保湿效果，并保持皮肤健康。