2,2-bis-(p-ethoxycarbonylmethoxyphenyl)propane | 42031-02-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,2-bis-(p-ethoxycarbonylmethoxyphenyl)propane
• 英文别名: diethyl 4,4'-isopropylidenebis(phenoxyacetate)；(4-[1-(4-ethoxycarbonylmethoxy-phenyl)-1-methyl-ethyl]-phenoxy)-acetic acid ethyl ester；ethyl 4-[1-(4-ethoxycarbonylmethoxyphenyl)-1-methylethyl]phenoxyacetate；ethyl 2-[4-[2-[4-(2-ethoxy-2-oxoethoxy)phenyl]propan-2-yl]phenoxy]acetate
• CAS: 42031-02-7
• 化学式: C₂₃H₂₈O₆
• 分子量: 400.472
• InChiKey: FRLBTVIUKGAIIA-UHFFFAOYSA-N

物化性质

• 熔点：
  23-24 °C
• 沸点：
  502.8±50.0 °C(Predicted)
• 密度：
  1.122±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  29
• 可旋转键数：
  12
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.39
• 拓扑面积：
  71.1
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  2,2-bis-(p-ethoxycarbonylmethoxyphenyl)propane 在 氢氧化钾 、 乙醇 、 盐酸 、 水 作用下， 以 四氢呋喃 为溶剂， 反应 20.0h， 生成 4,4'-异亚丙基二苯氧基乙酸
  参考文献：
  名称：

  Dihydroxy aromatic compounds and methods for preparation

  摘要：

  一种具有式(I)的二羟基芳香化合物，其中R1是C6-C60芳香二价官能团，R2在每个出现时可以相同或不同，并且在每个出现时独立地从由氰官能团、硝基官能团、卤素、具有1到10个碳的脂肪官能团、具有3到10个碳的环脂肪官能团和具有6到10个碳的芳香官能团组成的群中选择，而“n”是一个整数，其值为0到4。

  公开号：

  US07183431B1
• 作为产物：
  描述：

  双酚A 、 溴乙酸乙酯 在 potassium carbonate 作用下， 以 异丙醚 、 丙酮 为溶剂， 生成 2,2-bis-(p-ethoxycarbonylmethoxyphenyl)propane
  参考文献：
  名称：

  Tryptase inhibitors

  摘要：

  这项发明涉及用于制药工业生产药品的人类色氨酸蛋白酶的新型抑制剂。

  公开号：

  US06489327B1

文献信息

• Ultrasound-assisted synthesis of 2,5-dimethyl-N-substituted pyrroles catalyzed by uranyl nitrate hexahydrate
  作者：V.S.V. Satyanarayana、A. Sivakumar

  DOI：10.1016/j.ultsonch.2011.02.007

  日期：2011.9

  An efficient synthesis of different novel 2,5-dimethyl-N-substituted pyrrole derivatives by the Paal-Knorr condensation has been accomplished using uranyl nitrate hexahydrate as catalyst under soft conditions and ultrasonic irradiation. The synthesized compounds were confirmed through spectral characterization using IR, (1)H NMR, (13)C NMR and mass spectra.

  使用六水合铀酰硝酸铀酯在柔软条件下和超声辐射下，通过Paal-Knorr缩合反应成功合成了不同的新型2,5-二甲基-N-取代的吡咯衍生物。通过使用IR，（1）H NMR，（13）C NMR和质谱的光谱表征来确认合成的化合物。
• 1,5-Bis- (N-benzyl-N,N-diethylammoninm) diethylether, dichloride (BBDE C1). A novel bis-ammonium salt as phase transfer catalyst
  作者：Julio Alvarez-Builla、Juan J. Vaquero、Jose L. Garcia Navio、Juan F. Cabello、Carlos Sunkel、Miguel Fau de Casa-Juana、Fernando Dorrego、Luis Santos

  DOI：10.1016/s0040-4020(01)81376-4

  日期：1990.1
• Molecular Recognition of .beta.-Ribofuranosides by Synthetic Polypyridine-Macrocyclic Receptors
  作者：Masahiko Inouye、Toshiyuki Miyake、Masaru Furusyo、Hiroyuki Nakazumi

  DOI：10.1021/ja00155a006

  日期：1995.12

  Artificial ribofuranoside receptors were designed and synthesized. The design of the polypyridine-macrocyclic receptors was based on the multipoint hydrogen bond complementarity between the receptors and methyl beta-D-ribofuranoside. The binding affinity of the receptors for the ribofuranoside in CDCl3 was very high (up to K-a = 5.2 x 10(3) M(-1)), so that even native ribose was extracted by them into such nonpolar solvents. Selective extraction of ribose by the receptors\was observed: the extractabilities, or affinities to the receptors of various pentoses and hexoses decreased in the following order: ribose > deoxyribose congruent to lxyose congruent to xylose > fructose > arabinose > glucose congruent to mannose congruent to galactose. The selectivity is governed by the OH direction and the whole size of the sugars as well as their shapes. Furthermore, fluorescence emission of the receptors was largely enhanced in the presence of methyl beta-D-ribofuranoside or ribose, and the degree for the fluorescence enhancement by the addition of various sugars was almost compatible with that of the extractabilities. The polypyridine-macrocycles represent rationally designed multifunctional artificial receptors for ribofuranosides.
• DERBISHER V. E.; VALDMAN D. I., V SB. FUNKTS. ORGAN. SOEDINENIYA I POLIMERY. VOLGOGRAD, 1977, 17-21
  作者：DERBISHER V. E.、 VALDMAN D. I.

  DOI：——

  日期：——
• DIHYDROXY AROMATIC COMPOUNDS, METHODS FOR PREPARATION POLYMERS MADE THEREFROM, AND METHOD OF POLYMER PREPARATION
  申请人：SABIC Innovative Plastics IP B.V.

  公开号：EP1954741B1

  公开（公告）日：2010-12-22