N-tris (hydroxymethyl)methyl methacrylamide | 5001-88-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-tris (hydroxymethyl)methyl methacrylamide
• 英文别名: poly(N-tris[hydroxymethyl]methylmethacrylamide)；N-tris(hydroxymethyl) methylacrylamide；2-Methacryloylamino-2-hydroxymethyl-propan-1,3-diol；2-Propenamide, N-(2-hydroxy-1,1-bis(hydroxymethyl)ethyl)-2-methyl-；N-[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]-2-methylprop-2-enamide
• CAS: 5001-88-7
• 化学式: C₈H₁₅NO₄
• 分子量: 189.211
• InChiKey: PQWVIUSCFLEBHJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.7
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  89.8
• 氢给体数：
  4
• 氢受体数：
  4

安全信息

• 海关编码：
  2924199090

反应信息

• 作为产物：
  描述：

  三羟甲基氨基甲烷 、 甲基丙烯酰氯 以 硝基甲烷 为溶剂， 反应 18.0h， 以62.4%的产率得到N-tris (hydroxymethyl)methyl methacrylamide
  参考文献：
  名称：

  Brown, Eric; Loriot, Michel, Bulletin de la Societe Chimique de France, 1980, vol. 2, # 9-10, p. 481 - 489

  摘要：

  DOI：

文献信息

• Hydrogels from biopolymers
  申请人：Borbely Janos

  公开号：US20050238678A1

  公开（公告）日：2005-10-27

  Methods are disclosed for preparing linear or/and partial precross-linked poly-g-glutamic acid nanoparticle products, their reaction with compounds which contain vinyl groups, and the polymerization by chemical initiation or photopolymerization of these by light of predetermined wavelength. The final products of the present invention are useful as local drug delivery systems, dental surgery, and for inhibition of post-surgical adhesion. The hydrogels made from the biopolymers of the present invention may also be used in controlled release devices, superabsorbent materials and biomaterials like enzyme immobilization.

  本发明揭示了制备线性或/和部分预交联聚-γ-谷氨酸酸纳米颗粒产品的方法，以及它们与含有乙烯基团的化合物发生反应，并通过化学引发或光引发的聚合作用，使用特定波长的光。本发明的最终产品可用作局部药物输送系统、牙科手术以及用于抑制术后粘连。利用本发明的生物聚合物制成的水凝胶还可用于控释器件、超吸水材料和生物材料，如酶固定化。
• Polymeric electrolyte
  申请人：——

  公开号：US20010025790A1

  公开（公告）日：2001-10-04

  The invention relates to a polymeric electrolyte which is part of an electrochemical reference electrode and which is used in potentiometric and amperometric sensors. The polymeric electrolyte is a hydrogel which is stable in a large pH-range and stable against organic solvents.

  本发明涉及一种聚合物电解质，它是电化学参比电极的一部分，并用于电势计和安培计传感器中。该聚合物电解质是一种水凝胶，它在广泛的pH范围内稳定，并且稳定性能抵抗有机溶剂。
• CHELATING MONOMERS AND POLYMERS
  申请人：Zhang Hongmin

  公开号：US20070254378A1

  公开（公告）日：2007-11-01

  This invention provides chelating moieties that comprise an aryl group. Monomers that include the chelating moieties can be polymerized into chelating polymers. Chelating polymers are useful to chelate metals. Chelating polymers in the form of metal chelates are useful for binding analytes, such as polypeptides that comprise histidine residues. Chelating polymers can be includes in articles such as chips and chromatographic materials.

  本发明提供了包含芳基的螯合基团。包括螯合基团的单体可以聚合成螯合聚合物。螯合聚合物可用于螯合金属。以金属螯合物形式的螯合聚合物可用于结合分析物，例如包含组氨酸残基的多肽。螯合聚合物可以包含在芯片和色谱材料等物品中。
• Thermo-responsive polymer covalently bound with a peptide
  申请人：Saiani Alberto

  公开号：US20130281602A1

  公开（公告）日：2013-10-24

  A thermo-responsive polymer covalently bound with a peptide, wherein the peptide comprises a peptide moiety that is able to self-assemble and a functional peptide moiety comprising a bioactive sequence, and compositions comprising such thermo-responsive polymer covalently bound with a peptide. Methods for the preparation of such thermo-responsive polymers covalently bound with a peptide and the use thereof for the preparation of hydrogels.

  一种热响应性聚合物与肽共价结合，其中肽包括能够自组装的肽基团和包含生物活性序列的功能性肽基团，以及包含这种热响应性聚合物与肽的组合物。制备这种热响应性聚合物与肽共价结合的方法以及用于制备水凝胶的使用方法。
• Bioactive amino acid sequence and use therefrom
  申请人：Jeannin Laurent

  公开号：US20130210147A1

  公开（公告）日：2013-08-15

  Use of the amino acid sequence Har-Gly-Asp (hRGD) as a bioactive sequence in functional peptides to promote cell adhesion, cell growth, and/or cell differentiation, and in the preparation of hydrogels, preferably hydrogels for cell culture. A hydrogel comprising the hRGD sequence, especially a hydrogel wherein the hRGD sequence is part of the hydrogel scaffold.

  氨基酸序列Har-Gly-Asp(hRGD)被用作功能性肽中的生物活性序列，以促进细胞黏附、细胞生长和/或细胞分化，并用于制备水凝胶，特别是用于细胞培养的水凝胶。其中hRGD序列是水凝胶支架的一部分的水凝胶，尤其是包含hRGD序列的水凝胶。