bis[(4-methoxypyridin-2-yl)methyl][(pyridin-2-yl)methyl]amine | 870524-89-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: bis[(4-methoxypyridin-2-yl)methyl][(pyridin-2-yl)methyl]amine
• 英文别名: N,N-bis[(4-methoxypyridin-2-yl)methyl]-1-pyridin-2-ylmethanamine
• CAS: 870524-89-3
• 化学式: C₂₀H₂₂N₄O₂
• 分子量: 350.42
• InChiKey: ZSOMBZMUWFILTM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  26
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  60.4
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  ammonium hexafluorophosphate 、 diammonium hexachloroosmate(IV) 、 bis[(4-methoxypyridin-2-yl)methyl][(pyridin-2-yl)methyl]amine 以 乙二醇二甲醚 、 水 为溶剂， 反应 6.0h， 以95%的产率得到
  参考文献：
  名称：

  [EN] TRANSITION METAL COMPLEX CONTAINING TETRADENTATE NITROGEN DONOR LIGAND AND ELECTROCHEMICAL BIOSENSOR COMPRISING SAME
  [FR] COMPLEXE DE MÉTAL DE TRANSITION CONTENANT UN LIGAND DONNEUR D'AZOTE TÉTRADENTATE ET BIOCAPTEUR ÉLECTROCHIMIQUE LE COMPRENANT
  [KO] 테트라덴테이트 질소 공여체 리간드를 포함하는 전이금속 착체 및 이를 포함하는 전기화학적 바이오센서

  摘要：

  这项发明涉及包含四酰胺氮供体配体的新型过渡金属配合物，可用于各种装置，包括电化学传感器等。特别是，该发明涉及电化学传感器。

  公开号：

  WO2022145982A1
• 作为产物：
  描述：

  2-氨甲基吡啶 、 2-氯甲基-4-甲氧基吡啶盐酸盐 在 sodium carbonate 作用下， 以 乙腈 为溶剂， 反应 12.0h， 以60%的产率得到bis[(4-methoxypyridin-2-yl)methyl][(pyridin-2-yl)methyl]amine
  参考文献：
  名称：

  [EN] TRANSITION METAL COMPLEX CONTAINING TETRADENTATE NITROGEN DONOR LIGAND AND ELECTROCHEMICAL BIOSENSOR COMPRISING SAME
  [FR] COMPLEXE DE MÉTAL DE TRANSITION CONTENANT UN LIGAND DONNEUR D'AZOTE TÉTRADENTATE ET BIOCAPTEUR ÉLECTROCHIMIQUE LE COMPRENANT
  [KO] 테트라덴테이트 질소 공여체 리간드를 포함하는 전이금속 착체 및 이를 포함하는 전기화학적 바이오센서

  摘要：

  这项发明涉及包含四酰胺氮供体配体的新型过渡金属配合物，可用于各种装置，包括电化学传感器等。特别是，该发明涉及电化学传感器。

  公开号：

  WO2022145982A1

文献信息

• Correlation of Spin States and Spin Delocalization with the Dioxygen Reactivity of Catecholatoiron(III) Complexes
  作者：Masakazu Higuchi、Yutaka Hitomi、Hisataka Minami、Tsunehiro Tanaka、Takuzo Funabiki

  DOI：10.1021/ic051173y

  日期：2005.11.1

  significant in the low-spin species than in the high-spin species. The logarithm of the reaction rate constant is linearly correlated with the energy gap between the catecholatoiron(III) and semiquinonatoiron(II) states for the high-spin complexes 1-3, although complexes 4 and 5 deviate negatively from linearity. The lower reactivity of the low-spin complex, despite its higher spin density on the catecholate

  一系列儿茶酚铁（III）配合物[Fe（III）L（4Cl-cat）] BPh4（L =（4-MeO）2TPA（1），TPA（2），（4-Cl）2TPA（3）， （4-NO2）TPA（4），（4- ）2TPA（5）; TPA =三（吡啶-2-基甲基）胺; 4Cl-cat = 4-氯儿茶酚酸酯）已通过磁化率测量和EPR表征，1H NMR和UV-vis-NIR光谱学来阐明儿茶酚配体上的自旋离域与O2反应性以及O2反应性的自旋态相关性。冷冻的CH3CN在123 K下的EPR光谱清楚地表明，吸电子基团的引入有效地将自旋平衡从高自旋状态转变为低自旋状态。通过Evans方法在CH3CN溶液中测定的有效磁矩表明，在243 K时，5包含36％的低自旋物种，而1-4则主要处于高自旋状态。通过顺磁性1H NMR位移评估4Cl-cat配体上的自旋离域，发现低旋转物种中的半喹啉铁（II）特征比高旋转物种中的显着
• LIGANDS DESIGNED TO PROVIDE HIGHLY ACTIVE CATALYST COMPLEXES
  申请人：Carnegie Mellon University

  公开号：US20150087795A1

  公开（公告）日：2015-03-26

  A series of ligands with site specific electron donating substituents that form a catalyst complex with a transition metal and are suitable for catalysis of atom transfer radical reactions, including ATRP are described. Faster catalysis rates were observed allowing for low catalyst concentrations and linear increases in molecular weight with monomer conversion, and narrow molecular weight distributions. Cyclic voltammetry revealed that increasing the strength and number of conjugated electron donating groups resulted in more stable complexes and larger ATRP equilibrium constants.

  描述了一系列配体，具有特定位点的电子给体取代基，与过渡金属形成催化剂复合物，适用于催化原子转移自由基反应，包括ATRP。观察到更快的催化速率，允许低催化剂浓度和随单体转化率线性增加的分子量，以及较窄的分子量分布。循环伏安法揭示，增加共轭电子给体基团的强度和数量导致更稳定的复合物和更大的ATRP平衡常数。
• Surfactant assisted formation of a catalyst complex for emulsion atom transfer radical polymerization processes
  申请人：CARNEGIE MELLON UNIVERSITY

  公开号：US11174325B2

  公开（公告）日：2021-11-16

  Systems and methods for Atom Transfer Radical Polymerization (ATRP) emulsion polymerization are provided. The ATRP emulsion polymerization comprises a suspending medium, a dispersed medium, a surfactant, a transition metal compound in a higher oxidation state, a ligand, and an ATRP initiator. The transition metal compound is capable of forming a catalyst complex in a presence of the ligand. The catalyst complex is soluble in the suspending medium and is capable of forming an ionic complex with the surfactant. The ionic complex is capable of moving between the suspending medium and the dispersed medium. A portion of the transition metal compound in the higher oxidation state within a portion of the catalyst complex is reduced by a physical and/or a chemical procedure thereby initiating a polymerization of one or more radically (co)polymerizable monomers by reaction with the initiator.

  本发明提供了原子转移自由基聚合（ATRP）乳液聚合的系统和方法。ATRP 乳化聚合包括悬浮介质、分散介质、表面活性剂、高氧化态过渡金属化合物、配体和 ATRP 起始剂。过渡金属化合物能在配体存在下形成催化剂复合物。催化剂络合物可溶于悬浮介质，并能与表面活性剂形成离子络合物。离子络合物可在悬浮介质和分散介质之间移动。催化剂络合物的一部分中处于较高氧化态的过渡金属化合物通过物理和/或化学程序被还原，从而通过与引发剂反应引发一种或多种可辐射（共）聚合单体的聚合。
• SURFACTANT ASSISTED FORMATION OF A CATALYST COMPLEX FOR EMULSION ATOM TRANSFER RADICAL POLYMERIZATION PROCESSES
  申请人：CARNEGIE MELLON UNIVERSITY

  公开号：US20200055967A1

  公开（公告）日：2020-02-20

  Systems and methods for Atom Transfer Radical Polymerization (ATRP) emulsion polymerization are provided. The ATRP emulsion polymerization comprises a suspending medium, a dispersed medium, a surfactant, a transition metal compound in a higher oxidation state, a ligand, and an ATRP initiator. The transition metal compound is capable of forming a catalyst complex in a presence of the ligand. The catalyst complex is soluble in the suspending medium and is capable of forming an ionic complex with the surfactant. The ionic complex is capable of moving between the suspending medium and the dispersed medium. A portion of the transition metal compound in the higher oxidation state within a portion of the catalyst complex is reduced by a physical and/or a chemical procedure thereby initiating a polymerization of one or more radically (co)polymerizable monomers by reaction with the initiator.
• US9533297B2
  申请人：——

  公开号：US9533297B2

  公开（公告）日：2017-01-03