1,3-N-Dimethyl-5-methyl-benzimidazol-kation | 3204-28-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: 1,3-N-Dimethyl-5-methyl-benzimidazol-kation
• 英文别名: 1,3,5-trimethyl-2,3-dihydro-1H-benzoimidazole；2,3-Dihydro-1,3,5-trimethyl-1H-benzimidazole；1,3,5-trimethyl-2H-benzimidazole
• CAS: 3204-28-2
• 化学式: C₁₀H₁₄N₂
• 分子量: 162.235
• InChiKey: PEIQPWUCRHURBS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  6.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Amidate compound, catalyst for polyurethane production, and method for producing polyurethane resin
  申请人：KOEI CHEMICAL COMPANY, LIMITED

  公开号：US10689478B2

  公开（公告）日：2020-06-23

  Provided is an amidate compound represented by the formula (1): wherein A is a substituted or unsubstituted hydrocarbon group, n is an integer of 1 or more, and D is a nitrogen-containing organic group represented by the formula (2): wherein R1, R2, and R3 are the same or different, and are each a hydrocarbon group that may contain a heteroatom; some or all of R1, R2, and R3 may be bonded together to form a ring structure; X is a nitrogen atom, an oxygen atom, or a sulfur atom; and a is 0 or 1, wherein a is 1 when X is a nitrogen atom, and a is 0 when X is an oxygen atom or a sulfur atom.

  提供的是由式（1）表示的酰胺化合物：其中A是取代或未取代的碳氢基团，n是大于或等于1的整数，D是由式（2）表示的含氮有机基团：其中R1、R2和R3相同或不同，均为可能含有杂原子的碳氢基团；R1、R2和R3中的一些或全部可能结合在一起形成环结构；X是氮原子、氧原子或硫原子；a为0或1，当X为氮原子时，a为1，当X为氧原子或硫原子时，a为0。
• METHOD FOR PRODUCING AMIDATE COMPOUND, AND AMIDATE COMPOUND
  申请人：KOEI CHEMICAL COMPANY, LIMITED

  公开号：US20220048864A1

  公开（公告）日：2022-02-17

  A method for producing an amidate compound represented by Formula (4), comprising reacting an iminium salt represented by Formula (1) and an organic compound represented by Formula (3), wherein Formulas (1), (3), and (4) are as defined in the description.

  一种制备由式（4）表示的酰胺化合物的方法，包括反应由式（1）表示的亚胺盐和由式（3）表示的有机化合物，其中式（1）、式（3）和式（4）如描述中定义的那样。
• HETEROCYCLIC COMPOUND
  申请人：Takeda Pharmaceutical Company Limited

  公开号：EP3287441A1

  公开（公告）日：2018-02-28

  The present invention relates to a compound which can be useful for the treatment or prevention of SPT-related diseases including cancer and congenital diseases associated with sphingolipid accumulation (including Niemann-Pick disease).

  本发明涉及一种化合物，该化合物可用于治疗或预防与 SPT 有关的疾病，包括癌症和与鞘脂蓄积有关的先天性疾病（包括尼曼-皮克病）。
• CATALYST FOR DISSOCIATION OF BLOCKING AGENT FOR BLOCKED ISOCYANATES, AND THERMOSETTING COMPOSITION CONTAINING SAID CATALYST FOR DISSOCIATION OF BLOCKING AGENT
  申请人：Koei Chemical Company, Limited

  公开号：EP3689931A1

  公开（公告）日：2020-08-05

  A blocking agent dissociation catalyst for blocked isocyanates comprising a nitrogen-containing compound represented by Formula (1a): wherein D is represented by Formula (2): wherein R1, R2, R3, R4, and a are as described in the specification.

  一种用于封端异氰酸酯的封端剂解离催化剂，由式（1a）代表的含氮化合物组成： 其中 D 由式（2）表示： 其中 R1、R2、R3、R4 和 a 如说明书所述。
• ACYLATED 4-AMINOPIPERIDINES AS INHIBITORS OF SERINE PALMITOYLTRANSFERASE
  申请人：Takeda Pharmaceutical Company Limited

  公开号：EP3287441B1

  公开（公告）日：2021-06-09