methyl N-cyclooctylcarbamate | 2191-69-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: methyl N-cyclooctylcarbamate
• 英文别名: cyclooctyl-carbamic acid methyl ester
• CAS: 2191-69-7
• 化学式: C₁₀H₁₉NO₂
• 分子量: 185.266
• InChiKey: VHJIYQBTRVEPQR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  38.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  环辛胺 、 碳酸二甲酯 在 binder-free FeHY-mmm zeolite 作用下， 以 neat (no solvent) 为溶剂， 反应 1.0h， 以91%的产率得到methyl N-cyclooctylcarbamate
  参考文献：
  名称：

  Methoxycarbonylation of Alkyl-, Cycloalkyl-, and Arylamines with Dimethyl Carbonate in the Presence of Binder-Free Zeolite

  摘要：

  MethylN-alkyl-,N-cycloalkyl-, andN-arylcarbamates were synthesized by reaction of the corresponding amines with dimethyl carbonate in the presence of binder-free FeHY zeolite. The optimal conditions (reactant ratio, amount of the catalyst, temperature, reaction time) were found to afford the target products with high yields.

  DOI：

  10.1134/s1070428020070179

文献信息

• Methoxycarbonylation of Alkyl-, Cycloalkyl-, and Arylamines with Dimethyl Carbonate in the Presence of Binder-Free Zeolite
  作者：R. I. Khusnutdinov、N. A. Shchadneva、Yu. Yu. Mayakova、A. N. Khazipova

  DOI：10.1134/s1070428020070179

  日期：2020.7

  MethylN-alkyl-,N-cycloalkyl-, andN-arylcarbamates were synthesized by reaction of the corresponding amines with dimethyl carbonate in the presence of binder-free FeHY zeolite. The optimal conditions (reactant ratio, amount of the catalyst, temperature, reaction time) were found to afford the target products with high yields.