5(4H)-Oxazolone, 2,2'-(1,4-phenylene)bis(4-((4-methoxyphenyl)methylene)- | 51202-86-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 5(4H)-Oxazolone, 2,2'-(1,4-phenylene)bis(4-((4-methoxyphenyl)methylene)-
• 英文别名: (4E)-4-[(4-methoxyphenyl)methylidene]-2-[4-[(4E)-4-[(4-methoxyphenyl)methylidene]-5-oxo-1,3-oxazol-2-yl]phenyl]-1,3-oxazol-5-one
• CAS: 51202-86-9
• 化学式: C₂₈H₂₀N₂O₆
• 分子量: 480.5
• InChiKey: XZRFHDOOIZDXFC-DFEHQXHXSA-N

物化性质

• 密度：
  1.396g/cm3 at 20℃
• LogP：
  1.53 at 23℃ and pH7

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  36
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  95.8
• 氢给体数：
  0
• 氢受体数：
  8

文献信息

• COMPOSITION FOR THE TREATMENT OF NAIL FUNGUS
  申请人：Oystershell NV

  公开号：EP3884933A1

  公开（公告）日：2021-09-29

  The current invention relates to a composition for the topical treatment of fungal infections in nails, comprising at least one physiologically acceptable carboxylic acid capable of reducing the pH in keratinous tissue, in particular nails, of a treated person below 4.0, preferably in the range of 1.5 - 4.0, a physiologically acceptable carrier comprising at least one C1-C4 alkyl ester of lactic acid, and at least one physiologically acceptable fluorescent whitening agent. The invention relates to the use of said composition for the preparation of a product suitable for treatment of fungal infections. The invention also relates to the use of said composition for the treatment of a fungal infection.

  本发明涉及一种用于局部治疗指甲真菌感染的组合物，该组合物包含至少一种生理上可接受的羧酸，该羧酸能够将受治疗者的角质组织（尤其是指甲）中的 pH 值降至 4.0 以下，最好在 1.5 - 4.0 之间；一种生理上可接受的载体，该载体包含至少一种乳酸的 C1-C4 烷基酯；以及至少一种生理上可接受的荧光增白剂。本发明涉及使用所述组合物制备适用于治疗真菌感染的产品。本发明还涉及使用所述组合物治疗真菌感染。
• MOULDED OBJECT EXHIBITING A POLYCHROMATIC EFFECT, ASSOCIATED LIGHT DEVICE AND RESIN
  申请人：Arkema France

  公开号：EP1848763B1

  公开（公告）日：2008-04-16
• MIXER FOR MIXING A DENTAL COMPOSITION
  申请人：3M Innovative Properties Company

  公开号：EP2282692B1

  公开（公告）日：2013-06-26
• Moulded Object Exhibiting a Polychromatic Effect, Associated Light Device and Resin
  申请人：Peter Vlottes

  公开号：US20080214706A1

  公开（公告）日：2008-09-04

  The present invention relates to a moulded object made of a transparent and coloured plastic exhibiting a polychromatic effect, characterized in that the transparent plastic comprises from 0.1 to 1500 ppm of at least one fluorescent dye and from 50 to 10 000 ppm of at least one optical brightener. It also relates to the resin used for forming the moulded object. It also relates to a light device combining the said moulded object with at least one artificial light source which exhibits an emission in the region of excitation of the optical brightener, in particular in the 300-450 nm range, preferably 350-420 nm range, more preferably still 350-400 nm range.
• US7879927B2
  申请人：——

  公开号：US7879927B2

  公开（公告）日：2011-02-01