2-oxotetradecanoic acid | 25575-65-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-oxotetradecanoic acid
• 英文别名: 2-oxo-tetradecanoic acid；2-Oxo-tetradecansaeure；oxotetradecanoic acid；α-Keto-myristinsaeure
• CAS: 25575-65-9
• 化学式: C₁₄H₂₆O₃
• 分子量: 242.359
• InChiKey: QNAQCEOTTMFHDK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  17
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  54.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-oxotetradecanoic acid 在 4,4'-二氨基二苯乙烯-2,2'-二磺酸 作用下， 以 乙醚 、 二氯甲烷 为溶剂， 反应 2.25h， 生成 Methyl 2,2-difluorotetradecanoate
  参考文献：
  名称：

  Synthesis of α-difluoro and α-difluoro-β-trifluoroketo-derivatives as potential inhibitors for Cholesterol Ester Hydrolase

  摘要：

  Pancreatic Cholesterol Ester Hydrolase, a serine esterase, catalyzes the hydrolysis of cholesteryl esters in the gut. We report the convergent synthesis of alpha-difluoro-beta-trinuoroketo-(5,10,15) and of alpha-difluoroketo-derivatives (22,23) as inhibitors of this enzyme that were designed to generate stable tetrahedral reaction intermediates. Copyright (C) 1996 Elsevier Science Ltd

  DOI：

  10.1016/0960-894x(96)00290-9
• 作为产物：
  描述：

  4-十二烷基-3-苯基异恶唑啉-5-酮 在 甲酸 、 双氧水 、 三乙胺 作用下， 以 苯 为溶剂， 反应 15.0h， 生成 2-oxotetradecanoic acid
  参考文献：
  名称：

  Baldoli, Clara; Beccalli, Egle M.; Licandro, Emanuela, Gazzetta Chimica Italiana, 1981, vol. 111, # 7/8, p. 347 - 350

  摘要：

  DOI：

文献信息

• TEMPERATURE INDICATING DISPLAY DEVICE
  申请人：CHROMIC Co., Ltd.

  公开号：EP1560009A1

  公开（公告）日：2005-08-03

  A temperature indicating display device capable of displaying a thermo-history above a predetermined temperature reliably and irreversibly. Moreover, it is possible to provide a laminated body having a temperature detecting layer and an information recording film layer. When the temperature indicating display device is exposed to a predetermined temperature, an irreversible shift is caused and the temperature history can be displayed. Moreover, the temperature indicating display device includes an information recording film layer containing information, an information record holding layer for holding the information, and a temperature detection agent layer composed of a material whose state is shifted according to a temperature and is characterized in that when a predetermined temperature is detected, the material of the temperature detection agent layer is changed so as to change the display state of information recorded in the information recording layer. A laminated body using the temperature indicating display device, a vessel containing the device, and a labeled temperature indicating display device are also disclosed. Furthermore, the present invention provides a side-type temperature indicating display device in which a conventional information display member can be used as it is.

  一种温度指示显示装置，能够可靠且不可逆地显示超过预定温度的热历史。此外，还可以提供一种具有温度检测层和信息记录膜层的层压体。当温度显示装置暴露在预定温度下时，会产生不可逆的温度变化，从而显示温度历史记录。此外，温度显示装置还包括包含信息的信息记录膜层、用于保存信息的信息记录保持层，以及由根据温度改变状态的材料组成的温度检测剂层，其特征在于，当检测到预定温度时，温度检测剂层的材料发生变化，从而改变信息记录层中记录的信息的显示状态。本发明还公开了使用温度指示显示装置的层压体、装有该装置的容器和贴有标签的温度指示显示装置。此外，本发明还提供了一种侧面型温度指示显示装置，其中的传统信息显示部件可按原样使用。
• DETECTION OF RISK OF PRE-ECLAMPSIA
  申请人：University College Cork, National University of Ireland, Cork

  公开号：EP3422006A1

  公开（公告）日：2019-01-02

  A method for the early prediction of risk of hypertensive disorders in pregnant women, including for example eclampsia, mild pre-eclampsia, chronic hypertension, EPH gestosis, gestational hypertension, superimposed pre-eclampsia, HELLP syndrome, or nephropathy.

  一种早期预测孕妇高血压疾病风险的方法，例如包括子痫、轻度先兆子痫、慢性高血压、EPH妊娠中毒症、妊娠高血压、叠加先兆子痫、HELLP综合征或肾病。
• Detection of risk of pre-eclampsia
  申请人：UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK

  公开号：US10564146B2

  公开（公告）日：2020-02-18

  A method for the early prediction of risk of hypertensive disorders in pregnant women, including for example eclampsia, mild pre-eclampsia, chronic hypertension, EPH gestosis, gestational hypertension, superimposed pre-eclampsia, HELLP syndrome, or nephropathy.

  一种早期预测孕妇高血压疾病风险的方法，例如包括子痫、轻度先兆子痫、慢性高血压、EPH妊娠中毒症、妊娠高血压、叠加先兆子痫、HELLP综合征或肾病。
• Electrostatic ink compositions
  申请人：HP Indigo B.V.

  公开号：US10591838B2

  公开（公告）日：2020-03-17

  Disclosed herein is an electrostatic ink composition. The composition may comprise a carrier liquid, which has suspended therein: thermochromic pigment particles having a layer of thermoplastic resin thereon. Method for forming electrostatic ink composition and a substrate having the electrostatic ink composition printed thereon are also disclosed herein.

  本文公开了一种静电油墨组合物。该组合物可包括载液，载液中悬浮着热致变色颜料颗粒，颗粒上有一层热塑性树脂。本文还公开了形成静电油墨组合物的方法和印有静电油墨组合物的基材。
• Valcavi; Albertoni; Brandt, Arzneimittel-Forschung/Drug Research, 1989, vol. 39, # 10, p. 1190 - 1195
  作者：Valcavi、Albertoni、Brandt、Corsi、Farina、Foresta、Pascucci、Ramacci

  DOI：——

  日期：——