2,4-tricosadiynoic acid | 81009-20-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2,4-tricosadiynoic acid
• 英文别名: Tricosadiynoic acid；tricosa-2,4-diynoic acid
• CAS: 81009-20-3
• 化学式: C₂₃H₃₈O₂
• 分子量: 346.554
• InChiKey: YIQCSJRVSYPZPP-UHFFFAOYSA-N

物化性质

• 沸点：
  470.8±28.0 °C(Predicted)
• 密度：
  0.938±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  10.3
• 重原子数：
  25
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  3,6,9,12,15-五氧杂十七烷-1-醇 以 乙醇 、 氯仿 、 水 为溶剂， 生成 2,4-tricosadiynoic acid
  参考文献：
  名称：

  Ruaudel-Teixier, Molecular Crystals and Liquid Crystals (1969-1991), 1982, vol. 96, # 1-4, p. 365 - 372

  摘要：

  DOI：

文献信息

• Cells Containing a Nanopatch Sensor in Their Membrane
  申请人：Jelinek Raz

  公开号：US20070275433A1

  公开（公告）日：2007-11-29

  The present invention provides isolated cells comprising nanopatch sensors integrated into the cell membrane thereof, wherein said sensors are provided in the form of perturbation-sensitive constructs, and wherein said perturbation-sensitive constructs respond to perturbations of the cell membrane by means of a detectable change in one or more physical or chemical properties associated with said construct.

  本发明提供了包含纳米贴片传感器的孤立细胞，其中所述传感器集成到其细胞膜中，在所述传感器中以感扰敏构造的形式提供，并且所述感扰敏构造通过与所述构造相关的一个或多个物理或化学特性的可检测变化来响应细胞膜的扰动。
• POLY(METHYL METHACRYLATE)-SUPPORTED POLYDIACETYLENE FILMS AS COLORIMETRIC AND/OR FLUORESCENT DETECTORS
  申请人：B.G. NEGEV TECHNOLOGIES & APPLICATIONS LTD. AT BEN-GURION UNIVERSITY

  公开号：US20160041102A1

  公开（公告）日：2016-02-11

  Colorimetric and/or fluorescent detectors, which include a polydiacetylene (PDA) film deposited on a polymethylmetacrylate (PMMA) substrate. There are also colorimetric and/or fluorescent detectors which have a solid organic matrix comprising one or more PDAs deposited on the PMMA substrate, wherein the PDA includes polymerized units of one or more diacetylene monomers, and wherein the matrix further comprises at least one recognition element of an analyte. There are also methods for detecting analytes using this detector, uses thereof and a methods for its preparation.

  颜色计量和/或荧光检测器，包括沉积在聚甲基丙烯酸甲酯（PMMA）基板上的聚二烯烃（PDA）薄膜。还有一些颜色计量和/或荧光检测器，其具有包括沉积在PMMA基板上的一个或多个PDA的固体有机基质，其中PDA包括一个或多个二烯基单体的聚合单元，且基质进一步包括至少一种分析物的识别元素。还有使用该检测器检测分析物的方法，其用途以及其制备方法。
• HOLLOW FIBROUS ORGANIC NANOTUBE AND PRODUCTION METHOD THEREOF
  申请人：Asakawa Masumi

  公开号：US20090202641A1

  公开（公告）日：2009-08-13

  Disclosed is a method of synthesizing a water-free nanotube capable of efficiently encapsulating a functional substance therein, in large quantities. The method comprises: dissolving, in an organic solvent heated up to a temperature equal to or less than a boiling point thereof, an N-glycoside type glycolipid represented by the following general formula (1): G-NHCO—R 1 (wherein G represents a sugar residue from which a hemiacetal hydroxyl group bonded to an anomeric carbon atom of the sugar is excluded; and R 1 represents an unsaturated hydrocarbon group having 10 to 39 carbon atoms), or a peptide-lipid conjugate represented by one of the following general formulas (2) and (3): R 2 CO(NH—CHR 3 —CO) m OH and H(NH—CHR 3 —CO) m NHR 2 (wherein: R 2 represents a hydrocarbon group having 6 to 24 carbon atoms; R 3 represents an amino-acid side chain; and m represents an integer of 1 to 10); (i) slowly cooling the obtained solution, and maintaining the cooled solution undisturbed at room temperature, or (ii) concentrating the obtained solution, and maintaining the concentrated solution disturbed at room temperature, or (iii) adding to the obtained solution a poor solvent for the N-glycoside type glycolipid or the peptide-lipid conjugate, and maintaining the mixed solution undisturbed at room temperature; collecting from the resulting solution a hollow fibrous organic nanotube formed through self-assembling in the stationary solution, and drying the collected hollow fibrous organic nanotube, in air at room temperature or by heating under reduced-pressure, to obtain a hollow fibrous organic nanotube.

  本发明公开了一种合成无水纳米管的方法，该方法能够大量高效地封装功能物质。该方法包括：将下列通式（1）所表示的N-糖苷型糖脂或下列通式（2）和（3）所表示的肽-脂共轭物溶解于加热至沸点以下温度的有机溶剂中，其中，通式（1）中，G代表糖的缩合物，缩合物的半乙醇羟基与糖的缩合物的一个非环氧碳原子上的氢原子形成的羟基不包括在内；R1代表具有10至39个碳原子的不饱和烃基；通式（2）和（3）中，R2代表具有6至24个碳原子的碳氢基；R3代表氨基酸侧链；m代表1至10的整数。然后，（i）缓慢冷却所得溶液，并在室温下保持冷却的溶液不受干扰，或（ii）浓缩所得溶液，并在室温下保持浓缩的溶液受干扰，或（iii）向所得溶液中加入N-糖苷型糖脂或肽-脂共轭物的劣溶剂，并在室温下保持混合溶液不受干扰；从得到的溶液中收集在静止溶液中自组装形成的空心纤维有机纳米管，并通过在室温下空气干燥或在减压下加热干燥来获得空心纤维有机纳米管。
• HOLLOW-FIBER-LIKE ORGANIC NANOTUBE AND PROCESS FOR PRODUCTION THEREOF
  申请人：National Institute of Advanced Industrial Science and Technology

  公开号：EP2033934A1

  公开（公告）日：2009-03-11

  Disclosed is a method of synthesizing a water-free nanotube capable of efficiently encapsulating a functional substance therein, in large quantities. The method comprises: dissolving, in an organic solvent heated up to a temperature equal to or less than a boiling point thereof, an N-glycoside type glycolipid represented by the following general formula (1): G-NHCO-R1 (wherein G represents a sugar residue from which a hemiacetal hydroxyl group bonded to an anomeric carbon atom of the sugar is excluded; and R1 represents an unsaturated hydrocarbon group having 10 to 39 carbon atoms), or a peptide-lipid conjugate represented by one of the following general formulas (2) and (3): R2CO (NH-CHR3-CO)m OH and H (NH-CHR3-CO)m NHR2 (wherein: R2 represents a hydrocarbon group having 6 to 24 carbon atoms; R3 represents an amino-acid side chain; and m represents an integer of 1 to 10); (i) slowly cooling the obtained solution, and maintaining the cooled solution undisturbed at room temperature, or (ii) concentrating the obtained solution, and maintaining the concentrated solution disturbed at room temperature, or (iii) adding to the obtained solution a poor solvent for the N-glycoside type glycolipid or the peptide-lipid conjugate, and maintaining the mixed solution undisturbed at room temperature; collecting from the resulting solution a hollow fibrous organic nanotube formed through self-assembling in the stationary solution, and drying the collected hollow fibrous organic nanotube, in air at room temperature or by heating under reduced-pressure, to obtain a hollow fibrous organic nanotube.

  本发明公开了一种合成无水纳米管的方法，该纳米管能够大量有效地封装功能物质。该方法包括：在加热至等于或低于其沸点温度的有机溶剂中溶解由以下通式（1）表示的 N-糖苷型糖脂：G-NHCO-R1（其中 G 代表糖残基，其中与糖的异构碳原子结合的半缩醛羟基被排除；R1 代表具有 10 至 39 个碳原子的不饱和烃基），或由下列通式（2）和（3）之一代表的肽脂共轭物：R2CO（NH-CHR3-CO）m OH 和 H（NH-CHR3-CO）m NHR2（其中：R2 代表具有 6 至 24 个碳原子的烃基；R3 代表氨基酸侧链；m 代表 1 至 10 的整数）；(i) 缓慢冷却所得溶液，并将冷却后的溶液保持在室温下不受干扰，或 (ii) 浓缩所得溶液，并将浓缩后的溶液保持在室温下不受干扰，或 (iii) 向所得溶液中加入 N-糖苷型糖脂或肽脂共轭物的劣溶剂，并将混合溶液保持在室温下不受干扰；从所得溶液中收集在固定溶液中自组装形成的中空纤维状有机纳米管，并在室温空气中或通过减压加热干燥所收集的中空纤维状有机纳米管，以获得中空纤维状有机纳米管。
• Poly(methyl methacrylate)-supported polydiacetylene films as colorimetric and/or fluorescent detectors
  申请人：B.G. NEGEV TECHNOLOGIES & APPLICATIONS LTD. AT BEN-GURION UNIVERSITY

  公开号：US10101277B2

  公开（公告）日：2018-10-16

  Colorimetric and/or fluorescent detectors, which include a polydiacetylene (PDA) film deposited on a polymethylmetacrylate (PMMA) substrate. There are also colorimetric and/or fluorescent detectors which have a solid organic matrix comprising one or more PDAs deposited on the PMMA substrate, wherein the PDA includes polymerized units of one or more diacetylene monomers, and wherein the matrix further comprises at least one recognition element of an analyte. There are also methods for detecting analytes using this detector, uses thereof and a methods for its preparation.

  比色和/或荧光检测器，包括沉积在聚甲基丙烯酸甲酯（PMMA）基板上的聚二乙烯（PDA）薄膜。还有比色和/或荧光检测器，其固体有机基质包括沉积在 PMMA 基质上的一个或多个 PDA，其中 PDA 包括一个或多个二乙炔单体的聚合单元，基质还包括至少一个分析物的识别元素。此外，还有使用这种检测器检测分析物的方法、其用途及其制备方法。