(diphenylphosphanyl)(thiophenyl)methane | 82270-61-9

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: (diphenylphosphanyl)(thiophenyl)methane
• 英文别名: diphenylphosphino(phenylthio)methane；Diphenylphosphino(phenylthio)methan；diphenyl(phenylthiomethyl)phosphine；Ph2P(CH2)SPh；PCH2SPh；Phosphine, diphenyl[(phenylthio)methyl]-；diphenyl(phenylsulfanylmethyl)phosphane
• CAS: 82270-61-9
• 化学式: C₁₉H₁₇PS
• 分子量: 308.384
• InChiKey: SIXHVDSJIBKFHS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  25.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (diphenylphosphanyl)(thiophenyl)methane 以 乙醇 为溶剂， 生成
  参考文献：
  名称：

  Sanger, Alan R., Canadian Journal of Chemistry, 1983, vol. 61, p. 2214 - 2219

  摘要：

  DOI：
• 作为产物：
  描述：

  氯甲基苯硫醚 、 potassium diphenylphosphine 以 四氢呋喃 为溶剂， 以45%的产率得到(diphenylphosphanyl)(thiophenyl)methane
  参考文献：
  名称：

  Sanger, Alan R., Canadian Journal of Chemistry, 1983, vol. 61, p. 2214 - 2219

  摘要：

  DOI：

文献信息

• Reduction of tertiary phosphine oxides to phosphine-boranes using Ti(Oi-Pr)4/BH3-THF
  作者：Sylwia Sowa、K. Michał Pietrusiewicz

  DOI：10.1016/j.tet.2021.132057

  日期：2021.4

  A new method for reduction of tertiary phosphine oxides leading to the formation of tertiary phosphine-boranes has been developed. The BH3-THF/Ti(Oi-Pr)4 reducing system enables conversion of triaryl, diarylalkyl and trialkylphosphine oxides directly to their borane analogues in good to high yields. In contrast to the previously reported protocols, the presence of activating groups in the structure

  已经开发出一种用于还原叔膦氧化物的新方法，该方法导致形成叔膦硼烷。BH 3 -THF / Ti（O i -Pr）4还原系统能够将三芳基氧化物，二芳基烷基氧化物和三烷基膦氧化物直接转化为它们的硼烷类似物，并且产率高至高。与先前报道的方案相反，起始材料的结构中活化基团的存在对于反应的发生不是必需的。该反应是高度立体选择性的，并且主要保留在磷原子处的构型。已经提出了通过BH 3 -THF / Ti（O i -Pr）4还原P O键的合理机理。
• Ring Closure Kinetics of Bidentate Hemilabile P,N and P,S Ligands on a Platinum(II) Complex
  作者：Raffaello Romeo、Luigi Monsu’ Scolaro、Maria Rosaria Plutino、Andrea Romeo、Francesco Nicolo’、Alessandro Del Zotto

  DOI：10.1002/1099-0682(200203)2002:3<629::aid-ejic629>3.0.co;2-j

  日期：2002.3

  the cis-[PtPh2(CO)(η1-P−X)] complexes have been monitored in [D]chloroform by 1H and 31P1H} NMR. The rates of ring closure were found to be strongly dependent on the nature (S or N) and steric hindrance of the chelating end of the monocoordinated bidentate P−X ligand, and on the size of the ring formed. In contrast, ring size plays a negligible role, if any, in the dechelation reactions of cis-[PtPh2(S−S)]

  cis-[PtPh2(CO)(η1-P-N)] 和 cis-[PtPh2(CO)(η1-P-S)] 类型的复合物，其中双齿磷-氮和磷-硫配体与单齿金属中心 [PN = Ph2PC5H4N (Ph2PPy), Ph2P(CH2)2C5H4N (ppye), Ph2P(o-C6H4)NMe2 (PNMe2), Ph2P(CH2)nNMe2 (n = 2, 3, 即, peNMe2 和 ppNMe2) 和 PS = Ph2P(CH2)2SEt (P-SEt), Ph2P(CH2)nSPh (n = 1, 2, 即 P-CH2SPh 和 P-SPh)]，通过反应原位制备具有顺式-[PtPh2(CO)(SEt2)]的杂化配体的分析。在每种情况下，第一个观察到的过程是二乙基硫醚被磷酰基快速取代，导致单取代的开环顺式-[PtPh2(CO)(η1-PX)] (X = N 或 S) 复合物，通过 1H 和 31P1H}
• Cationic complexes of rhodium(I) as catalysts in the homogeneous O2-oxidation of terminal alkenes to methyl ketones
  作者：Mario Bressan、Franco Morandini、Antonino Morvillo、Pierluigi Rigo

  DOI：10.1016/0022-328x(85)87071-6

  日期：1985.1

  [Rh(LL)2]+, [Rh(LL)(diene)]+ and [Rh(LL)S2]+ complexes are effective as catalysts for the oxidation by dioxygen of terminal olefins to methyl ketones. The complexes act as monooxygenases, the second oxygen atom being transferred to the alcohol solvent.

  [Rh（LL）2 ] +，[Rh（LL）（二烯）] +和[Rh（LL）S 2 ] +络合物有效地用作末端烯烃的双氧氧化为甲基酮的催化剂。络合物起单加氧酶的作用，第二个氧原子被转移到醇溶剂中。
• Cationic arene ruthenium(ii) complexes with chelating P-functionalized alkyl phenyl sulfide and sulfoxide ligands as potent anticancer agents
  作者：Gerd Ludwig、Goran N. Kaluđerović、Tobias Rüffer、Martin Bette、Marcus Korb、Michael Block、Reinhard Paschke、Heinrich Lang、Dirk Steinborn

  DOI：10.1039/c3dt33064h

  日期：——

  The synthesis and characterization of cationic ruthenium(II) complexes of the type [Ru(η6-p-cym)ClPh2P(CH2)nS(O)xPh-κP,κS}][PF6] (n = 1–3; x = 0, 1; p-cym = p-cymene) are presented. Furthermore, their high biological potential even against cisplatin-resistant tumor cell lines and their structure–activity relationships are discussed.

  合成和阳离子钌的表征（II类型）的复合物的[Ru（η 6 - p -cym）氯博士2 P（CH 2）ñ S（O）X PH-κ P，κ小号}] [PF 6 ]（n = 1-3; x = 0，1; p -cym =对苯甲基）。此外，还讨论了它们即使对顺铂耐药的肿瘤细胞株也具有很高的生物学潜力，并探讨了它们的结构-活性关系。
• Rhodium(I) complexes with κP coordinated ω-phosphinofunctionalized alkyl phenyl sulfide, sulfoxide and sulfone ligands and their reactions with sodium bis(trimethylsilyl)amide and Ag[BF4]
  作者：Michael Block、Martin Bette、Christoph Wagner、Jürgen Schmidt、Dirk Steinborn

  DOI：10.1016/j.jorganchem.2010.12.019

  日期：2011.5

  trinuclear cationic rhodium(I) complex [Rh3(μ-Cl)(μ-Ph2PCH2SPh-κP:κS)4][BF4]2·4THF (12·4THF) with a four-membered Rh3Cl ring as basic framework. Addition of sodium bis(trimethylsilyl)amide to complexes 6–11 led to a selective deprotonation of the carbon atom neighbored to the S(O)x group (α-C) yielding three different types of organorhodium complexes: a) Organorhodium intramolecular coordination compounds of

  ω-二苯基膦基官能化的烷基苯基硫化物Ph 2 P（CH 2）n SPh（n  = 1，1a ; 2，2a ; 3，3a）与亚砜Ph 2 P（CH 2）n S（O）Ph（n  = 1，1B ; 2，2B ; 3，3B）和砜博士2 P（CH 2）ñ S（O）2 Ph（上ñ  = 1，1C ; 2，2C ; 3，3C）与双核氯桥联的铑（I）配合物[（RhL 2）2（μ-Cl）2 ]（L 2  =环辛基-1.5-二烯，cod，4 ;双（二苯基膦基）乙烷，dppe，5）得到单核Rh （I）所述类型的配合物[的RhCl博士2 P（CH 2）ñ S（O）X PH-κ P }（COD）] 1（ñ / X  = 1/0，图6a ; 1/1，6B ; 1/2，图6c ; 2/0，图8a ; 2/1，8B ; 2/2，8C ; 3/0，10a的; 3/ 1，10b ; 3/2，10C）和[的RhCl博士2 P（CH