The invention relates to antimicrobial compositions which contain
(i) at least one zinc compound selected from zinc salt and zinc oxide,
(ii) at least one glycerine monoalkyl ether of the general formula
R-O-CH2-CHOH-CH2OH,
wherein R is a branched or unbranched C1-C24 alkyl group, wherein the alkyl group can be substituted with one or more hydroxy and/or C1-C4 alkoxy group(s) and/or the alkyl chain can be interrupted by up to four oxygen atoms,
(iii) at least one antioxidant and
optionally
(iv) one or more alkanediols,
wherein the weight ratio (w/w) of component (ii) to component (iii) is at least 10:1.
The compositions are used in cosmetic and pharmaceutical products and already have broad antimicrobial activity, in particular against Pseudomonas aeruginosa, at active substance contents of only about 3 wt.%.
本发明涉及抗菌组合物,其中含有
(i) 至少一种选自
锌盐和
氧化锌的
锌化合物、
(ii) 至少一种通式如下的
甘油单烷基醚
R-O-
CH2-CHOH- OH、
其中 R 是支化或未支化的 C1-C24 烷基,烷基可被一个或多个羟基和/或 C1-C4 烷氧基取代和/或烷基链可被最多四个氧原子打断、
(iii) 至少一种
抗氧化剂和
任选地
(iv) 一种或多种烷二醇、
其中成分(ii)与成分(iii)的重量比(w/w)至少为 10:1。
这些组合物可用于化妆品和医药产品,在活性物质含量仅为 3 wt.%左右时,已具有广泛的抗菌活性,特别是针对
铜绿假单胞菌。