2-(1,4-dioxan-2-yl)pyrazine | 33787-79-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 2-(1,4-dioxan-2-yl)pyrazine
• CAS: 33787-79-0
• 化学式: C₈H₁₀N₂O₂
• 分子量: 166.18
• InChiKey: PUNSTEVWRHMXFZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.9
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  44.2
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  1,4-二氧六环 、 吡嗪 在 dipotassium peroxodisulfate 作用下， 以 水 、 丙酮 为溶剂， 反应 6.0h， 以40%的产率得到2-(1,4-dioxan-2-yl)pyrazine
  参考文献：
  名称：

  Cross-dehydrogenative coupling of α-C(sp³)–H of ethers/alkanes with C(sp²)–H of heteroarenes under metal-free conditions

  摘要：

  报道了一种无金属的α-氧代烷基/烷基自由基与电子不足的杂环芳烃之间的交叉脱氢偶联方法。

  DOI：

  10.1039/c5ob01268f

文献信息

• Persulfate-Enabled Direct C–H Alkylation of Heteroarenes with Unactivated Ethers
  作者：Louis Barriault、Terry McCallum、Laurie-Anne Jouanno、Alexandre Cannillo

  DOI：10.1055/s-0035-1561338

  日期：——

  Protocol simplification is an important aspect in the development of organic reactions such as heteroarene functionalizations. An operationally facile protocol for the direct C–H alkylation of heteroarenes with unactivated ethers has been developed. The Minisci-type radical addition process involves thermolysis of potassium persulfate, circumventing the need for transition-metal catalysts.

  协议简化是开发有机反应（如杂芳烃功能化）的一个重要方面。已经开发了一种使用未活化醚直接对杂芳烃进行 C-H 烷基化的操作简便的方案。Minisci 型自由基加成过程涉及过硫酸钾的热解，无需过渡金属催化剂。
• Visible light-promoted C–H functionalization of ethers and electron-deficient arenes
  作者：Shekaraiah Devari、Bhahwal Ali Shah

  DOI：10.1039/c5cc08817h

  日期：——

  Photocatalyst-free visible-light-mediated C–H arylation of ethers via C_(Sp2)–C_(Sp3) C–H functionalization involving hydrogen atom transfer (HAT) pathway.

  无需光催化剂的可见光介导醚的C–H芳基化反应，通过涉及氢原子转移（HAT）途径的C_(Sp2)–C_(Sp3) C–H官能团化实现。

• Nucleophilic character of alkyl radicals—V
  作者：W. Buratti、G.P. Gardini、F. Minisci、F. Bertini、R. Galli、M. Perchinunno

  DOI：10.1016/s0040-4020(01)97776-2

  日期：1971.1

  good yields and the complete selectivity obtained are due to the nucleophilic character of the α-oxyalkyl radicals. A quantitative study concerning the nucleophilic character of the dioxanyl radical, carried out by measuring the relative rates of attack on 4-substituted quinolines; revealed in detail all the features of nucleophilic substitutions.

  已经通过各种氧化剂将α-氧基烷基直接引入杂芳族碱中：过氧化氢，叔丁基氢过氧化物，过氧二硫酸铵，过硼酸钠和双（4-叔丁基环己基）-过氧化二碳酸酯。由于α-氧烷基的亲核特性，所以获得了良好的产率和完全的选择性。通过测量4-取代喹啉的相对进攻速率，进行了有关二恶烷基自由基亲核特性的定量研究；揭示了亲核取代的所有特征。
• ELECTRICITY STORAGE DEVICE
  申请人：NEC Corporation

  公开号：EP1381100A1

  公开（公告）日：2004-01-14

  A charge storage device such as a battery, wherein a positive electrode comprises a nitroxyl compound having a structure of a nitroxyl cation moiety represented by formula (I) in an oxidized state while having a structure of a nitroxyl radical moiety represented by formula (II) in a reduced state and a reaction represented by reaction formula (A) in which an electron is transferred between these states is used as a positive electrode reaction. The charge storage device can have a higher energy density and can be used at a large current.

  一种蓄电装置（如电池），其正极由硝基化合物组成，该硝基化合物在氧化态具有由式（I）表示的硝基阳离子分子结构，在还原态具有由式（II）表示的硝基自由基分子结构，正极反应由反应式（A）表示，其中电子在这些状态之间转移。这种电荷储存装置的能量密度较高，可在较大电流下使用。
• Electricity storage device
  申请人：——

  公开号：US20040115529A1

  公开（公告）日：2004-06-17

  A charge storage device such as a battery, wherein a positive electrode comprises a nitroxyl compound having a structure of a nitroxyl cation moiety represented by formula (I) in an oxidized state while having a structure of a nitroxyl radical moiety represented by formula (II) in a reduced state and a reaction represented by reaction formula (A) in which an electron is transferred between these states is used as a positive electrode reaction. The charge storage device can have a higher energy density and can be used at a large current. 1

  一种蓄电装置（如电池），其正极由硝基化合物组成，该硝基化合物在氧化态具有由式（I）表示的硝基阳离子分子结构，在还原态具有由式（II）表示的硝基自由基分子结构，正极反应由反应式（A）表示，其中电子在这些状态之间转移。该电荷储存装置可具有更高的能量密度，并可在大电流下使用。 1