Dimethoxyphosphorylselanylmethylbenzene | 1608108-19-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Dimethoxyphosphorylselanylmethylbenzene
• 英文别名: dimethoxyphosphorylselanylmethylbenzene
• CAS: 1608108-19-5
• 化学式: C₉H₁₃O₃PSe
• 分子量: 279.134
• InChiKey: DHBKLBUQTJJAEX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.29
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  二苄基二硒醚 、 亚磷酸二甲酯 在 锌 作用下， 以 乙醇 为溶剂， 反应 0.5h， 以71%的产率得到Dimethoxyphosphorylselanylmethylbenzene
  参考文献：
  名称：

  Environmentally benign synthesis and antimicrobial study of novel chalcogenophosphates

  摘要：

  We report in this work an environmentally benign zinc mediated synthesis of aryl and benzyl phosphorochalcogenoates in ethanol within a short reaction time. In vitro antimicrobial study along with statistical analysis and seed germination assay were performed. These chalcogenophosphates possess strong antimicrobial activity against the reference strains. The antibacterial activity was determined against four standard strains (Bacilus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa). The antifungal activity was evaluated against one fungal strain Candida albicans. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2014.03.008

文献信息

• Environmentally benign synthesis and antimicrobial study of novel chalcogenophosphates
  作者：Shubhanjan Mitra、Sayani Mukherjee、Sukanta K. Sen、Alakananda Hajra

  DOI：10.1016/j.bmcl.2014.03.008

  日期：2014.5

  We report in this work an environmentally benign zinc mediated synthesis of aryl and benzyl phosphorochalcogenoates in ethanol within a short reaction time. In vitro antimicrobial study along with statistical analysis and seed germination assay were performed. These chalcogenophosphates possess strong antimicrobial activity against the reference strains. The antibacterial activity was determined against four standard strains (Bacilus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa). The antifungal activity was evaluated against one fungal strain Candida albicans. (C) 2014 Elsevier Ltd. All rights reserved.