ergosta-7,22-diene-3-one | 1431-87-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: ergosta-7,22-diene-3-one
• 英文别名: ergosta-7,22-dien-3-one；(5S,9R,10S,13R,14R,17R)-17-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-10,13-dimethyl-1,2,4,5,6,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
• CAS: 1431-87-4
• 化学式: C₂₈H₄₄O
• 分子量: 396.657
• InChiKey: AHWOEMBXZXGDBQ-LLSCCSQYSA-N

物化性质

• 沸点：
  485.2±44.0 °C(Predicted)
• 密度：
  0.99±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  7.3
• 重原子数：
  29
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  ergosta-7,22-diene-3-one 在 吡啶 、 乙醇 、 sodium 作用下， 生成 benzoic acid-(5α-ergostadien-(7.22t)-yl-(3β)-ester)
  参考文献：
  名称：

  Laucht, Hoppe-Seyler's Zeitschrift fur Physiologische Chemie, 1937, vol. 246, p. 171,174

  摘要：

  DOI：
• 作为产物：
  描述：

  麦角固醇 在 二氧化碳 、 镍 作用下， 生成 ergosta-7,22-diene-3-one
  参考文献：
  名称：

  Laucht, Hoppe-Seyler's Zeitschrift fur Physiologische Chemie, 1937, vol. 246, p. 171,174

  摘要：

  DOI：

文献信息

• Forecasting Peak Daily Ozone Levels—I. A Regression with Time Series Errors Model Having a Principal Component Trigger to Fit 1991 Ozone Levels
  作者：Pao-Wen Grace Liu、Richard Johnson

  DOI：10.1080/10473289.2002.10470841

  日期：2002.9

  model for the peak daily 1-hr ozone level is proposed. A Regression with Time Series Errors (RTSE) model, which includes a principal component (PC) trigger, is the basis for forecasting the peak daily 1-hr ozone level. The RTSE model, with a PC trigger, is first employed to estimate daily peak ozone measured at the University of Wisconsin, Milwaukee-North (UWM-N), during the 1991 ozone season. The RTSE

  这项研究的动机是需要在高臭氧日警告威斯康星州密尔沃基的人口。提出了每天1小时臭氧峰值水平的统计模型。具有时间序列误差的回归（RTSE）模型（包括一个主要成分（PC）触发器）是预测每天1小时峰值臭氧水平的基础。带有PC触发器的RTSE模型首先用于估算1991年臭氧季节在密尔沃基北部的威斯康星大学（UWM-N）测得的每日峰值臭氧。RTSE模型使用每日峰值温度，早晨矢量平均风向和PC触发作为预测变量。PC触发器旨在总结臭氧峰值大于十亿分之100（ppb）时的大气情况。经验证，带有PC触发器的RTSE模型，大大改善了每日峰值臭氧的预测，特别是峰值臭氧大于100 ppb的预测。与没有PC触发的RTSE模型相比，带有PC触发的RTSE模型将R2从0.680提升到0.809。建议使用PC触发的RTSE模型是适当的统计模型，具有实时臭氧预报的潜力。
• Notes - A New Method for the Activation of Copper Chromium Oxide as a Reducing Catalyst
  作者：William Nes

  DOI：10.1021/jo01100a603

  日期：1958.6
• 271. The application of the method of molecular rotation differences to steroids. Part V. Olefinic unsaturation at the 7 : 8-position
  作者：D. H. R. Barton、J. D. Cox

  DOI：10.1039/jr9480001354

  日期：——
• Film Formation in EHL Point Contacts under Zero Entraining Velocity Conditions
  作者：F. Guo、P. L. Wong、P. Yang、K. Yagi

  DOI：10.1080/10402000208982583

  日期：2002.1

  The contacts of adjacent bulls in a retainerless bearing are subjected to the zero entrainment velocity (ZEV). The existence of an effective elastohydrodynamic lubrication (EHL) film between contacts running tinder ZEV conditions has long been proven experimentally. However, the classical EHL theory predicts a Zero film thickness under ZEV conditions. Mechanisms, such as the thermal viscosity wedge effect and immobile film theory, have been proposed to tentatively explain the phenomenon. However, detailed numerical results are needed to provide theoretical evidence for such film formations. This paper aims to simulate, based on the viscosity wedge mechanism, the film formation of EHL point contacts tinder ZEV conditions. Complete numerical solutions have been successfully obtained. The results show, that the thermal viscosity wedge induces a concave film profile, instead of a parallel film (Hertzian) as postulated by sonic previous researchers. By the simulation solver developed, the variation of film thickness with loads, oil supply conditions and ellipticity, parameters have been investigated. Some unique lubrication behaviors tinder ZEV conditions are demonstrated. Furthermore, preliminary quantitative comparisons with the latest optical EHL experiments are finished. Both results are in good correlation.
• Windaus; Auhagen, Justus Liebigs Annalen der Chemie, 1929, vol. 472, p. 185,190, 193
  作者：Windaus、Auhagen

  DOI：——

  日期：——