2,2'-dihydroxy-6,6'-di-isopropyl-3,3'-dimethylbiphenyl | 87327-16-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,2'-dihydroxy-6,6'-di-isopropyl-3,3'-dimethylbiphenyl
• 英文别名: 2-(2-hydroxy-6-isopropyl-3-methylphenyl)-3-isopropyl-6-methylphenol；3,3'-di-isopropyl-6,6'-dimethyl-2,2'-biphenol；2-(2-Hydroxy-3-methyl-6-propan-2-ylphenyl)-6-methyl-3-propan-2-ylphenol
• CAS: 87327-16-0
• 化学式: C₂₀H₂₆O₂
• 分子量: 298.425
• InChiKey: XNDOOEKEJJRKAR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  香芹酚 在 二叔丁基过氧化物 作用下， 反应 24.0h， 生成 2,2'-dihydroxy-6,6'-di-isopropyl-3,3'-dimethylbiphenyl 、 2-hydroxy-5',6-di-isopropyl-2',3-dimethyldiphenyl ether
  参考文献：
  名称：

  Armstrong, David R.; Cameron, Colin.; Nonhebel, Derek C., Journal of the Chemical Society. Perkin transactions II, 1983, p. 587 - 590

  摘要：

  DOI：

文献信息

• Synthesis, atropoisomerism and chemistry of the dimers of R-(−)-carvone, R-(−)-hydrocarvone, 1R,5R-(+)-pinocarvone and other monoterpenic ketones
  作者：Marco Mazzega、Fabrizio Fabris、Sergio Cossu、Ottorino De Lucchi、Vittorio Lucchini、Giovanni Valle

  DOI：10.1016/s0040-4020(99)00131-3

  日期：1999.4

  Oxidative homocoupling of R-(−)-carvone 4, R-(−)-hydrocarvone 21, 1R,5R-(+)-pinocarvone25 and other monoterpenic ketones leads to the respective C2-symmetric dimers 6, 20 and 26 in most cases as single diastereoisomers. Subsequent reactions of dimeric compounds were investigated in detail. Other monoterpenes (menthone, pulegone) undergo homocoupling in low yields and poor diastereoselectivity.

  的氧化自偶联- [R - （ - ） -香芹酮4，- [R - （ - ） - hydrocarvone 21，1 - [R，5 - [R - （+） -松香芹酮25和其他单萜酮引线于相应Ç 2 -对称二聚体6,20和在大多数情况下为26个单一非对映异构体。详细研究了二聚体化合物的后续反应。其他单萜（薄荷酮，普勒高酮）以低收率和较差的非对映选择性进行均偶联。
• Process for preparing 3,3',6,6'-tetraalkyl-2,2'-biphenols and 3,3',6,6'-tetraalkyl-5,5'-dihalo-2,2'-biphenols
  申请人：——

  公开号：US20040049087A1

  公开（公告）日：2004-03-11

  A process for making a compound of the formula I 1

  制备化合物I1的过程
• Process for preparation of polymeric, phosphorus-containing compositions
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP1586598A1

  公开（公告）日：2005-10-19

  A polymeric, phosphorus-containing composition derived from aryl to aryl coupling of a substituted 2,2'-dihydroxyl-1,1'-binaphthalene or a substituted 2,2'-dihydroxyl-1,1'-biphenylene and phosphonylated at the dioxyl of said structure with at least one diaryloxyphosphite [-P(-O-Ar)2], diarylphosphine [-P(Ar)2] and/or aryl, aryloxyphosphinite [-P(Ar)(-O-Ar)], where each Ar is individually phenyl, substituted phenyl, naphthyl, and substituted naphthyl, provided that the two Ar groups that are directly or indirectly bonded to the same phosphorus atom may be linked to each other by a linking unit selected from direct bond, alkylidene, secondary or tertiary amine, oxygen, sulfide, sulfone, and sulfoxide. Polymerization by aryl to aryl coupling is achieved by direct oxidative coupling of the binaphthalene or biphenylene, copolymerization with an aromatic comonomer, or copolymerization with an aldehyde. The phosphonylation may be performed prior to or after polymerization. The polymeric, phosphorus-containing compositions in combination with a Group VIII metal and, optionally a Lewis acid, are particularly useful in the catalytic hydrocyanation of unsaturated organic compounds, isomerization of unsaturated, branched nitriles to unsaturated linear nitriles, and hydroformylation of unsaturated organic compounds.

  一种聚合物含磷组合物，由取代的 2,2'-二羟基-1,1'-联萘或取代的 2,2'-二羟基-1、或取代的 2,2'-二羟基-1,1'-联苯，并在所述结构的二恶英处用至少一种二芳基亚磷酸[-P(-O-Ar)2]、二芳基膦[-P(Ar)2]和/或芳基、芳氧基膦[-P(Ar)(-O-Ar)]进行膦酰化、其中每个 Ar 单独为苯基、取代苯基、萘基和取代萘基，但直接或间接键合到同一磷原子上的两个 Ar 基团可通过选自直接键、亚烷基、仲胺或叔胺、氧、硫化物、砜和亚砜的连接单元相互连接。芳基与芳基的偶联聚合可通过二萘或联苯的直接氧化偶联、与芳香族共聚单体的共聚或与醛的共聚来实现。膦酰化可在聚合之前或之后进行。聚合物、含磷组合物与第八族金属和路易斯酸（可选）结合，特别适用于不饱和有机化合物的催化加氢氰化、不饱和支链腈与不饱和线性腈的异构化以及不饱和有机化合物的加氢甲酰化。
• Supported bis(phosphorus) ligands and their use in the catalysis
  申请人：——

  公开号：US20030153691A1

  公开（公告）日：2003-08-14

  Supported bis(phosphorus) ligands are disclosed for use in a variety of catalytic processes, including the isomerization, hydrogenation, hydroformylation, and hydrocyanation of unsaturated organic compounds. Catalysts are formed when the ligands are combined with a catalytically active metal, such as nickel.

  已公开的支撑双（磷）配体可用于各种催化过程，包括不饱和有机化合物的异构化、氢化、加氢甲酰化和加氢氰酸化。 当配体与催化活性金属（如镍）结合时，就形成了催化剂。
• POLYMERIC, PHOSPHOROUS-CONTAINING COMPOSITIONS AND THEIR USE IN HYDROCYANATION, ISOMERIZATION AND HYDROFORMYLATION REACTIONS
  申请人：E. I. du Pont de Nemours and Company

  公开号：EP1448668A1

  公开（公告）日：2004-08-25