2,2'-dicarboxyhydrazobenzene | 612-44-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,2'-dicarboxyhydrazobenzene
• 英文别名: 2.2'-Dicarboxy-hydrazobenzol；2,2'-Hydrazobenzoesaeure；2,2'-Hydrazobenzoldicarbonsaeure；Hydrazobenzol-o,o'-dicarbonsaeure；Hydrazobenzol-2,2'-dicarbonsaeure；N,N'-Bis-(2-carboxy-phenyl)-hydrazin；2,2'-diazane-1,2-diyl-bis-benzoic acid；Hydrazobenzol-dicarbonsaeure-(2.2')；2,2'-Hydrazo-di-benzoesaeure；2,2'-hydrazo-di-benzoic acid；2,2'-hydrazobis-benzoic acid；o.o'-Hydrazobenzoesaeure；2,2'-(Hydrazine-1,2-diyl)dibenzoic acid；2-[2-(2-carboxyphenyl)hydrazinyl]benzoic acid
• CAS: 612-44-2
• 化学式: C₁₄H₁₂N₂O₄
• 分子量: 272.26
• InChiKey: FSDLEWUVLGMHRV-UHFFFAOYSA-N

物化性质

• 沸点：
  417.8±45.0 °C(Predicted)
• 密度：
  1.501±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  98.7
• 氢给体数：
  4
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  2,2'-dicarboxyhydrazobenzene 在 硫酸 作用下， 生成 4,4'-二氯联苯
  参考文献：
  名称：

  Schultz; Rohde; Vicari, Justus Liebigs Annalen der Chemie, 1907, vol. 352, p. 130

  摘要：

  DOI：
• 作为产物：
  描述：

  邻硝基苯甲酸 在 sodium hydroxide 、 锌 、 盐酸 作用下， 以 乙醇 、 水 为溶剂， 反应 24.0h， 以18%的产率得到2,2'-dicarboxyhydrazobenzene
  参考文献：
  名称：

  具有侧挂酸碱功能的偶氮苯/偶氮苯偶合中的质子偶合电子转移。氢键和结构效应

  摘要：

  带有两个羧酸基团的偶氮苯衍生物中的电子转移在标题 2e(-) + 2H(+) 氧化还原对中以逐步方式与分子内质子转移偶联。侧链酸碱官能团的存在将偶氮/氢偶氮对的氧化还原化学推向正电位高达 0.75 V。这基本上是相邻羧基和氮原子之一氢键的结果。一个羧酸盐与相邻质子化氮原子的 H 键合。两次电子转移反应，特别是第二次，伴随着强烈的结构变化，导致出现电子转移和结构变化不协调的方形机制。

  DOI：

  10.1021/ja504484a

文献信息

• Radioimmune method of assaying quantitatively for a hapten
  申请人：Biological Developments, Inc.

  公开号：US03940475A1

  公开（公告）日：1976-02-24

  A radioimmune method of assaying quantitatively for a hapten comprising contacting an aqueous sample containing the hapten under assay, a known quantity of a radioactively labeled marker which incorporates a hapten homologous to the hapten under assay, and an insolubilized antibody specific for the hapten under assay to competitively bind part of said labeled hapten and the hapten contained in said sample to the antibody; incubating the foregoing mixture until a two-phase system is produced comprising an insoluble or solid phase and an aqueous phase, and measuring the radioactivity of at least one of said two phases, the value of said radioactivity being a function of the concentration in said sample of the hapten under assay.

  一种放射免疫测定法，用于定量测定半抗原，包括将待测含有半抗原的水样与已知量的含有与待测半抗原同源的半抗原的放射性标记物和特异于待测半抗原的抗体的不溶化合物接触，使标记的半抗原的一部分和样品中含有的半抗原竞争性地与抗体结合；孵育上述混合物直至产生包含不溶性或固体相和水相的两相系统，并测量至少其中一相的放射性，所述放射性的值是样品中待测半抗原的浓度的函数。
• Immunochemical assay method
  申请人：Biological Developments, Inc.

  公开号：US04097586A1

  公开（公告）日：1978-06-27

  Haptens and antigen derivatives are coupled, through an azo bond, to proteins to form a conjugated material. The conjugate is injected into laboratory animals to raise antibodies which are useful in immunochemically assaying for the original haptens and antigen derivatives. Included among the immunochemical assay methods are radio-immune assays and fluorescence methods.

  半抗原和抗原衍生物通过偶氮键与蛋白质偶联，形成共轭材料。将这种共轭物注射到实验动物体内，以产生对原始半抗原和抗原衍生物有用的抗体，用于免疫化学测定。免疫化学测定方法包括放射免疫测定和荧光方法。
• The relationship of bisanthranil to its structural isomer and related compounds
  作者：G. K. J. Gibson、A. S. Lindsey、H. M. Paisley

  DOI：10.1039/j39670001792

  日期：——

  A spectroscopic, mass spectroscopic, and chemical examination of bisanthranil, m. p. 185°, and of its structural isomer, m. p. 302°, has confirmed the lactone structure of the former and the amide structure of the latter. The spectra were compared with those of 2-phenylindazol-3-one, 2-(2-carboxyphenyl)indazol-3-one, 2-phenyl-3,1-benzoxazin-4-one, isatoic anhydride, and dianthranilide.

  光谱分析，质谱分析和化学检测联苯乙腈，mp 185°及其结构异构体mp 302°，已确认前者的内酯结构和后者的酰胺结构。将该光谱与2-苯基吲哚-3-酮，2-（2-羧苯基）吲唑-3-酮，2-苯基-3,1-苯并恶嗪-4-酮，异丙酸酐和二蒽酰苯胺的光谱进行比较。
• METHOD FOR TREATING SURFACE OF SUBSTRATE AND SURFACE TREATMENT COMPOSITION THEREFOR
  申请人：MITSUBISHI CHEMICAL CORPORATION

  公开号：EP0789071A1

  公开（公告）日：1997-08-13

  A method for treating the surface of a substrate with a surface treatment composition, wherein the surface treatment composition comprises a liquid medium containing a complexing agent as a metal deposition preventive, the complexing agent comprising at least one member selected from the following Group A complexing agents and at least one member selected from the group consisting of the following Groups B1 to B6 complexing agents: Group A:complexing agents having an aromatic hydrocarbon ring in the molecular structure thereof and at least one of an OH group and/or an O- group bonded directly to a carbon atom constituting the ring; Group B1:complexing agents having at least one nitrogen atom as a donor atom in the molecular structure thereof; Group B2:complexing agents having at least one atom selected from halogen, sulfur and carbon atoms as a donor atom in the molecular structure thereof; Group B3:complexing agents having at least one oxygen atom as a donor atom in the molecular structure thereof, but not having a carbonyl group and a carboxyl group and not having any one of nitrogen, halogen, sulfur and carbon atoms as a donor atom; Group B4:carboxylic acid type complexing agents having at least one carboxyl group in the molecular structure thereof, but not having any one of nitrogen, halogen, sulfur and carbon atoms as a donor atom and not having a carbonyl group and a hydroxyl group; Group B5:hydroxymono- or di-carboxylic acid type complexing agents having at most 4 hydroxyl groups in the molecular structure thereof, but not having any one of nitrogen, halogen, sulfur and carbon atoms as a donor atom and not having a carbonyl group; and Group B6:complexing agents having at least one carbonyl group in the molecular structure thereof.

  一种用表面处理组合物处理基材表面的方法，其中表面处理组合物包括含有络合剂作为金属沉积防止剂的液体介质，络合剂包括至少一种选自以下A组络合剂的成员和至少一种选自以下B1至B6组络合剂组成的组的成员： A 组：络合剂，其分子结构中具有一个芳香烃环，且至少有一个 OH 基团和/或 O- 基团直接与构成该环的碳原子键合； B1组：络合剂，其分子结构中至少有一个氮原子作为供体原子； B2组：络合剂，其分子结构中至少有一个原子作为供体原子，该原子选自卤素、硫和碳原子； B3组:络合剂，其分子结构中至少有一个氧原子作为供体原子，但没有羰基和羧基，也没有氮、卤素、硫和碳原子中的任何一个原子作为供体原子； B4组：羧酸类络合剂，其分子结构中至少有一个羧基，但没有氮、卤素、硫和碳原子中的任何一个原子作为供体原子，也没有羰基和羟基； B5 组：分子结构中最多有 4 个羟基，但不以氮、卤素、硫和碳原子中的任一个作 为供体原子，且不含羰基的羟基单羧酸或二羧酸类络合剂；以及 B6 组：分子结构中至少有一个羰基的络合剂。
• Method for treating surface of substrate and surface treatment composition used for the same
  申请人：Mitsubishi Chemical Corporation

  公开号：US20020045556A1

  公开（公告）日：2002-04-18

  A method for treating the surface of a substrate with a surface treatment composition, wherein the surface treatment composition comprises a liquid medium containing a complexing agent as a metal deposition preventive, the complexing agent comprising at least one member selected from Group A complexing agents and at least one member selected from Group B complexing agents as defined hereinafter.

  一种用表面处理组合物处理基底表面的方法，其中表面处理组合物包括含有络合剂作为金属沉积预防剂的液体介质，络合剂包括至少一种选自下文定义的 A 组络合剂和至少一种选自 B 组络合剂的成员。