(+-)-1r-ethyl-5-methoxy-3c-(4-methoxy-phenyl)-2t-methyl-indan

• 分子结构分类: 有机化合物 - 苯类化合物 - 茚满类
• 英文名称: (+-)-1r-ethyl-5-methoxy-3c-(4-methoxy-phenyl)-2t-methyl-indan
• 英文别名: 1r-ethyl-2t-methyl-3c-(4-methoxyphenyl)-5-methoxyindane；(+/-)-1r-Aethyl-5-methoxy-3c-(4-methoxy-phenyl)-2t-methyl-indan；(+/-)-5-Methoxy-2t-methyl-1r-aethyl-3c-(4-methoxy-phenyl)-indan；(1S,2S,3S)-1-ethyl-5-methoxy-3-(4-methoxyphenyl)-2-methyl-2,3-dihydro-1H-indene
• 化学式: C₂₀H₂₄O₂
• 分子量: 296.409
• InChiKey: BOHWTLGMDYVWAE-ROOHIHILSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (+-)-1r-ethyl-5-methoxy-3c-(4-methoxy-phenyl)-2t-methyl-indan 在 磷化氢 、 氢碘酸 作用下， 生成 3,5-dinitro-benzoic acid-(1-ethyl-2-methyl-indan-5-yl ester)
  参考文献：
  名称：

  Zur Polymerisation des Isosafrols und des Isoeugenolmethyl�thers

  摘要：

  DOI：

  10.1007/bf00898699
• 作为产物：
  描述：

  1-(4-甲氧苯基)丙烷-1-OL 在 硫酸 作用下， 生成 (+-)-1r-ethyl-5-methoxy-3c-(4-methoxy-phenyl)-2t-methyl-indan
  参考文献：
  名称：

  Fishing and Farming at Lake Chad: Responses to Lake-level Fluctuations

  摘要：

  Lake Chad lies at the southern extreme of the Sahara Desert and is well known for large fluctuations in its surface area this century. Seasonal fluctuations, however, have received much less attention. This paper presents the results of two complimentary research efforts on the south‐west shore of the lake. These illustrate how important both inter and intra‐annual fluctuations in the level of the lake are, both in terms of their impact on the environment and in the response of the communities living on the lake shore. The paper compares a time series of the fluctuations in the level of Lake Chad as monitored by the TOPEX/POSEIDON satellite with findings from participatory research with the communities of the south‐west lake shore. It shows how the communities of the lake have responded to lake‐level fluctuations with their livelihood choices. These results are used to show that although vastly different in scope, a high degree of complimentarity exists between remotely‐sensed information and community‐based research and that they are of potentially great value to development initiatives on the shores of Lake Chad.

  DOI：

  10.1111/j.1475-4959.2000.tb00015.x

文献信息

• Scope of the formal [3+2] cycloaddition for the synthesis of substituted 3-arylindanes and related compounds
  作者：Beatriz Lantaño、José Manuel Aguirre、Esteban Ariel Ugliarolo、María Laura Benegas、Graciela Yolanda Moltrasio

  DOI：10.1016/j.tet.2008.02.034

  日期：2008.4

  We report the single step synthesis of several 3-arylindanes and related compounds via a formal [3+2] cycloaddition. A study of the influence of the aromatic ring substitution pattern on the reaction was carried out.

  我们通过一个正式的[3 + 2]环加成反应报告了几个3-芳基茚满和相关化合物的一步合成。进行了芳香环取代方式对反应的影响的研究。
• Determination of Major Aroma Impact Compounds in Fermented Cucumbers by Solid-Phase Microextraction--Gas Chromatography--Mass Spectrometry--Olfactometry Detection
  作者：R. T. Marsili、N. Miller

  DOI：10.1093/chromsci/38.7.307

  日期：2000.7.1

  Purge-and-trap, solid-phase extraction, and solid-phase microextraction-gas chromatography-mass spectrometry (SPME—GC—MS) sample preparation techniques for the analysis of odor impact chemicals in fermented cucumber brine are compared. SPME—GC—MS is coupled with detection frequency olfactometry experiments to determine key impact odor compounds in the brine. The most potent odorants that define the typical characteristic brine aroma are trans-4-hexenoic acid and cis-4-hexerioic acid. Confirmation of key impact odorants in brine is confirmed by recombination experiments.

  比较了用于分析发酵黄瓜盐水中影响气味的化学物质的净化捕集、固相萃取和固相微萃取-气相色谱-质谱（SPME-GC-MS）样品制备技术。SPME-GC-MS 与检测频率嗅觉测定实验相结合，可确定盐水中主要的影响气味化合物。确定盐水典型特征香气的最有效气味物质是反式-4-己烯酸和顺式-4-己二酸。通过重组实验确认了盐水中的主要影响气味化合物。
• Mueller; Richl, Chemische Berichte, 1943, vol. 76, p. 1119,1123
  作者：Mueller、Richl

  DOI：——

  日期：——
• van der Zanden; de Vries, Recueil des Travaux Chimiques des Pays-Bas, 1955, vol. 74, p. 52,56
  作者：van der Zanden、de Vries

  DOI：——

  日期：——
• Mueller et al., Chemische Berichte, 1944, vol. 77/79, p. 766,774
  作者：Mueller et al.

  DOI：——

  日期：——