1-deoxy-D-tagatose | 4233-67-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 1-deoxy-D-tagatose
• 英文别名: (3S,4S,5R)-3,4,5,6-tetrahydroxyhexan-2-one
• CAS: 4233-67-4
• 化学式: C₆H₁₂O₅
• 分子量: 164.158
• InChiKey: IXDZFGATLNCIOI-PBXRRBTRSA-N

物化性质

• 熔点：
  143-145 °C
• 沸点：
  455.3±45.0 °C(Predicted)
• 密度：
  1.417±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -2.6
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  98
• 氢给体数：
  4
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  1-deoxy-D-tagatose 在 吡啶 、 copper(I) sulfate 、 硫酸 作用下， 反应 24.0h， 生成
  参考文献：
  名称：

  A new synthesis of 1-deoxy-d-psicose and 1-deoxy-d-tagatose

  摘要：

  DOI：

  10.1016/0008-6215(85)85231-9
• 作为产物：
  描述：

  2-氨基-2-脱氧-D-半乳糖盐酸盐 在 镍 盐酸 、 2,6-二叔丁基苯醌 作用下， 以 甲醇 、 水 为溶剂， 反应 42.5h， 生成 1-deoxy-D-tagatose
  参考文献：
  名称：

  A convenient synthesis of 1-deoxy-d-tagatose

  摘要：

  DOI：

  10.1016/s0008-6215(00)85261-1

文献信息

• DEOXYKETOHEXOSE ISOMERASE AND METHOD FOR PRODUCING DEOXYHEXOSE AND DERIVATIVE THEREOF USING SAME
  申请人：Izumori Ken

  公开号：US20100105885A1

  公开（公告）日：2010-04-29

  Providing 1- or 6-deoxy products corresponding to all of aldohexoses, ketohexoses and sugar alcohols, as based on Deoxy-Izumoring, as well as a method for systematically producing those products. A method for producing deoxyketohexose and a derivative thereof using a deoxyketohexose isomerase derived from Pseudomonas cichorii ST-24 (FERM BP-2736), comprising epimerizing 1-deoxy D-ketohexose or 6-deoxy D-ketohexose or 1-deoxy L-ketohexose or 6-deoxy L-ketohexose at position 3 to produce the individually corresponding 1-deoxy D-ketohexose or 6-deoxy D-ketohexose or 1-deoxy L-ketohexose or 6-deoxy L-ketohexose as an intended product.

  提供对应于所有己醛糖、己酮糖和糖醇的1-或6-去氧产物，基于去氧-Izumoring，以及一种系统生产这些产物的方法。一种使用来自Pseudomonas cichoriiST-24（FERM BP-2736）的去氧己酮糖异构酶生产去氧己酮糖及其衍生物的方法，包括将1-去氧D-己酮糖或6-去氧D-己酮糖或1-去氧L-己酮糖或6-去氧L-己酮糖在3号位置上对映异构化为各自对应的1-去氧D-己酮糖或6-去氧D-己酮糖或1-去氧L-己酮糖或6-去氧L-己酮糖作为预期产物。
• Deoxyketohexose isomerase and method for producing deoxyhexose and derivative thereof using same
  申请人：Izumori Ken

  公开号：US08389248B2

  公开（公告）日：2013-03-05

  Providing 1- or 6-deoxy products corresponding to all of aldohexoses, ketohexoses and sugar alcohols, as based on Deoxy-Izumoring, as well as a method for systematically producing those products. A method for producing deoxyketohexose and a derivative thereof using a deoxyketohexose isomerase derived from Pseudomonas cichorii ST-24 (FERM BP-2736), comprising epimerizing 1-deoxy D-ketohexose or 6-deoxy D-ketohexose or 1-deoxy L-ketohexose or 6-deoxy L-ketohexose at position 3 to produce the individually corresponding 1-deoxy D-ketohexose or 6-deoxy D-ketohexose or 1-deoxy L-ketohexose or 6-deoxy L-ketohexose as an intended product.

  提供所有醛糖、酮糖和糖醇对应的1-或6-去氧产物，基于Deoxy-Izumoring，以及一种系统生产这些产物的方法。使用源自Pseudomonas cichorii ST-24 (FERM BP-2736)的去氧酮糖异构酶，包括在位置3上使1-去氧D-酮糖、6-去氧D-酮糖、1-去氧L-酮糖或6-去氧L-酮糖发生外消旋反应，以生产相应的1-去氧D-酮糖、6-去氧D-酮糖、1-去氧L-酮糖或6-去氧L-酮糖作为预期产物的方法。
• DEOXYKETOHEXOSE ISOMERASE AND METHOD FOR PRODUCING DEOXYKETOHEXOSE AND DERIVATIVE THEREOF USING THE SAME
  申请人：National University Corporation Kagawa University

  公开号：EP2161332A1

  公开（公告）日：2010-03-10

  Providing 1- or 6-deoxy products corresponding to all of aldohexoses, ketohexoses and sugar alcohols, as based on Deoxy-Izumoring, as well as a method for systematically producing those products. A method for producing deoxyketohexose and a derivative thereof using a deoxyketohexose isomerase derived from Pseudomonas cichorii ST-24 (FERM BP-2736), comprising epimerizing 1-deoxy D-ketohexose or 6-deoxy D-ketohexose or 1-deoxy L-ketohexose or 6-deoxy L-ketohexose at position 3 to produce the individually corresponding 1-deoxy D-ketohexose or 6-deoxy D-ketohexose or 1-deoxy L-ketohexose or 6-deoxy L-ketohexose as an intended product.

  提供与所有醛己糖、酮己糖和糖醇相对应的1-或6-脱氧产品，如基于脱氧偶氮的产品，以及系统生产这些产品的方法。一种使用源自 Pseudomonas cichorii ST-24 的脱氧酮己糖异构酶（FERM BP-2736）生产脱氧酮己糖及其衍生物的方法、包括将1-脱氧D-酮己糖或6-脱氧D-酮己糖或1-脱氧L-酮己糖或6-脱氧L-酮己糖在位置3处外嵌，以产生单独对应的1-脱氧D-酮己糖或6-脱氧D-酮己糖或1-脱氧L-酮己糖或6-脱氧L-酮己糖作为目的产物。
• Isomerization of deoxyhexoses: green bioproduction of 1-deoxy-d-tagatose from l-fucose and of 6-deoxy-d-tagatose from d-fucose using Enterobacter agglomerans strain 221e
  作者：Akihide Yoshihara、Satoshi Haraguchi、Pushpakiran Gullapalli、Davendar Rao、Kenji Morimoto、Goro Takata、Nigel Jones、Sarah F. Jenkinson、Mark R. Wormald、Raymond A. Dwek、George W.J. Fleet、Ken Izumori

  DOI：10.1016/j.tetasy.2008.02.013

  日期：2008.4

  1-Deoxy-D-tagatose was produced by the hydrogenation of 6-deoxy-L-galactose (L-fucose) to L-fucitol followed by oxidation with Enterobacter agglomerans 221e; a similar sequence on D-fucose afforded 6-deoxy-D-tagatose. Thus, the polylol dehydrogenase recognizes the D-galacto-configuration of both D-fucitol and L-fucitol. The procedures were conducted in water and show the power of green, environmentally friendly biotechnology in the preparation of new monosaccharides with a potential for novel bioactive properties. 6-Deoxy-D-tagatose was also synthesized from D-tagatose via the efficient formation of 1,2:3,4-di-O-isopropylidene-alpha-D-tagatofuranose; a difficult final removal of protecting groups by acid makes the biotechnological route more attractive. (c) 2008 Elsevier Ltd. All rights reserved.
• Yokota, Akira; Sasajima, Ken-ichi, Agricultural and Biological Chemistry, 1984, vol. 48, # 6, p. 1643 - 1646
  作者：Yokota, Akira、Sasajima, Ken-ichi

  DOI：——

  日期：——