N-(3-methyl-2-pyridyl)-N-[(E)-3-phenyl-2-propenyl]amine | 256379-28-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(3-methyl-2-pyridyl)-N-[(E)-3-phenyl-2-propenyl]amine
• 英文别名: 3-methyl-N-[(E)-3-phenylprop-2-enyl]pyridin-2-amine
• CAS: 256379-28-9
• 化学式: C₁₅H₁₆N₂
• 分子量: 224.305
• InChiKey: JZYVVVKZCBQSAN-UXBLZVDNSA-N

物化性质

• 沸点：
  413.2±33.0 °C(Predicted)
• 密度：
  1.100±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  24.9
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N-(3-methyl-2-pyridyl)-N-[(E)-3-phenyl-2-propenyl]amine 在 十二羰基三钌 盐酸 作用下， 以 甲苯 为溶剂， 反应 6.0h， 生成 1-phenylnonan-3-one
  参考文献：
  名称：

  Catalytic Activation of C−H and C−C Bonds of Allylamines via Olefin Isomerization by Transition Metal Complexes

  摘要：

  The metal-catalyzed reaction of olefins with allylamines bearing coordination sites (2-pyridyl groups) was studied. With Ru-3(CO)(12) as catalyst, activation of C-H bonds led to the formation of ketimines that were hydrolyzed to give asymmetric ketones. With [(C8H14)(2)RhCl](2), both C-H and C-C bonds were activated and symmetric ketones were formed on hydrolysis. The reaction involves double bond migration of the allylamine to form an aldimine.

  DOI：

  10.1021/ol990357b
• 作为产物：
  描述：

  2-氨基-3-甲基吡啶 、 肉桂基氯 在 正丁基锂 作用下， 以 四氢呋喃 为溶剂， 生成 N-(3-methyl-2-pyridyl)-N-[(E)-3-phenyl-2-propenyl]amine
  参考文献：
  名称：

  Catalytic Activation of C−H and C−C Bonds of Allylamines via Olefin Isomerization by Transition Metal Complexes

  摘要：

  The metal-catalyzed reaction of olefins with allylamines bearing coordination sites (2-pyridyl groups) was studied. With Ru-3(CO)(12) as catalyst, activation of C-H bonds led to the formation of ketimines that were hydrolyzed to give asymmetric ketones. With [(C8H14)(2)RhCl](2), both C-H and C-C bonds were activated and symmetric ketones were formed on hydrolysis. The reaction involves double bond migration of the allylamine to form an aldimine.

  DOI：

  10.1021/ol990357b

文献信息

• Synthesis of Cycloalkanones from Dienes and Allylamines through CbH and CbC Bond Activation Catalyzed by a Rhodium(I) Complex This work was supported by the National Research Laboratory Program (2000-N-NL-01-C-271) administered by Ministry of Science and Technology, and by the Korean Science and Engineering Foundation (20004010).
  作者：Dae-Yon Lee、In-Jung Kim、Chul-Ho Jun

  DOI：10.1002/1521-3773(20020816)41:16<3031::aid-anie3031>3.0.co;2-x

  日期：2002.8.16
• Cleavage of Carbon−Carbon Triple Bond of Alkyne via Hydroiminoacylation by Rh(I) Catalyst
  作者：Chul-Ho Jun、Hyuk Lee、Choong Woon Moon、Hye-Sook Hong

  DOI：10.1021/ja011053z

  日期：2001.9.1
• Catalytic Activation of C−H and C−C Bonds of Allylamines via Olefin Isomerization by Transition Metal Complexes
  作者：Chul-Ho Jun、Hyuk Lee、Jae-Bum Park、Dae-Yon Lee

  DOI：10.1021/ol990357b

  日期：1999.12.1

  The metal-catalyzed reaction of olefins with allylamines bearing coordination sites (2-pyridyl groups) was studied. With Ru-3(CO)(12) as catalyst, activation of C-H bonds led to the formation of ketimines that were hydrolyzed to give asymmetric ketones. With [(C8H14)(2)RhCl](2), both C-H and C-C bonds were activated and symmetric ketones were formed on hydrolysis. The reaction involves double bond migration of the allylamine to form an aldimine.