sedumoside A₃ | 933776-88-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: sedumoside A₃
• 英文别名: (2R,3R,4S,5S,6R)-2-[(2S)-2-hydroxy-4-[(1S,4S,6R)-4-hydroxy-2,2,6-trimethylcyclohexyl]butoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
• CAS: 933776-88-6
• 化学式: C₁₉H₃₆O₈
• 分子量: 392.49
• InChiKey: FIZSLWJZMGGTNP-IVBSIHMHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  27
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  140
• 氢给体数：
  6
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  sedumoside A₃ 在 水 、 β-glucosidase 作用下， 反应 16.0h， 以95%的产率得到sarmentol A
  参考文献：
  名称：

  Megastigmanes and Their Glucosides from the Whole Plant of Sedum sarmentosum

  摘要：

  Two new megastigmanes, sarmentoic acid (1) and sarmentol A (2), and six new megastigmane glucosides, sedumosides A(1) (3), A(2) (4), A(3) (5), B (6), C (7), and D (8), were isolated from the whole plant of Sedum sarmentosum together with eight known megastigmanes (9-16). The absolute stereostructures of 1-8 were elucidated on the basis of chemical and physicochemical evidence, including the application of the modified Mosher's method.

  DOI：

  10.1021/np068059s
• 作为产物：
  描述：

  sedumoside C 在 sodium tetrahydroborate 作用下， 以 甲醇 为溶剂， 反应 0.5h， 以14%的产率得到sedumoside A₃
  参考文献：
  名称：

  Megastigmanes and Their Glucosides from the Whole Plant of Sedum sarmentosum

  摘要：

  Two new megastigmanes, sarmentoic acid (1) and sarmentol A (2), and six new megastigmane glucosides, sedumosides A(1) (3), A(2) (4), A(3) (5), B (6), C (7), and D (8), were isolated from the whole plant of Sedum sarmentosum together with eight known megastigmanes (9-16). The absolute stereostructures of 1-8 were elucidated on the basis of chemical and physicochemical evidence, including the application of the modified Mosher's method.

  DOI：

  10.1021/np068059s

文献信息

• Megastigmanes and Their Glucosides from the Whole Plant of <i>Sedum sarmentosum</i>
  作者：Masayuki Yoshikawa、Toshio Morikawa、Yi Zhang、Seikou Nakamura、Osamu Muraoka、Hisashi Matsuda

  DOI：10.1021/np068059s

  日期：2007.4.1

  Two new megastigmanes, sarmentoic acid (1) and sarmentol A (2), and six new megastigmane glucosides, sedumosides A(1) (3), A(2) (4), A(3) (5), B (6), C (7), and D (8), were isolated from the whole plant of Sedum sarmentosum together with eight known megastigmanes (9-16). The absolute stereostructures of 1-8 were elucidated on the basis of chemical and physicochemical evidence, including the application of the modified Mosher's method.