5-butoxy-valeric acid | 70160-07-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 5-butoxy-valeric acid
• 英文别名: 5-Butyloxy-valeriansaeure；5-Butoxy-valeriansaeure；5-Butoxypentanoic acid
• CAS: 70160-07-5
• 化学式: C₉H₁₈O₃
• 分子量: 174.24
• InChiKey: ZVCZLVOPBPNSIP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  12
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  5-溴戊酸 、 sodium butanolate 生成 5-butoxy-valeric acid
  参考文献：
  名称：

  Fieser et al., Journal of the American Chemical Society, 1948, vol. 70, p. 3209

  摘要：

  DOI：

文献信息

• Phospholipid Ether Analogs as Cancer-Targeting Drug Vehicles
  申请人：Cellectar Biosciences, Inc.

  公开号：US20160136190A1

  公开（公告）日：2016-05-19

  The present invention is directed to therapeutic compounds capable of targeting cancer cells and cancer stem cells. The present invention is further directed to compositions comprising these therapeutic compounds and methods of treating cancer comprising administering these therapeutic compounds.

  本发明旨在针对癌细胞和癌干细胞的治疗化合物。本发明进一步涉及包含这些治疗化合物的组合物和治疗癌症的方法，其中包括给予这些治疗化合物。
• Epithiolone Analogues
  申请人：Tillekeratne Viranga

  公开号：US20090258904A1

  公开（公告）日：2009-10-15

  Epothilone analogues include a molecular scaffold which holds at least one segment of epothilone in a predetermined orientation and which rigidities a region between the macrolactone ring and the aromatic side-chain.

  Epothilone类似物包括一个分子支架，该支架以预定的方向保持至少一个epothilone片段，并使大环内酯环和芳香侧链之间的区域变得坚硬。
• GLS1 INHIBITORS FOR TREATING DISEASE
  申请人：Board of Regents, The University of Texas System

  公开号：US20160002204A1

  公开（公告）日：2016-01-07

  Disclosed herein are compounds and compositions useful in the treatment of GLS1 mediated diseases, such as cancer, having the structure of Formula I: Methods of inhibition GLS1 activity in a human or animal subject are also provided.

  本文披露了一些具有I式结构的化合物和组合物，可用于治疗GLS1介导的疾病，例如癌症。同时，还提供了抑制人类或动物主体中GLS1活性的方法。
• Process for producing 2-acylfuran derivatives
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0268820A2

  公开（公告）日：1988-06-01

  2-acylfuran derivatives (R: alkyl, phenyl, etc.; R1: H, alkyl) are prepared in high yield by reaction, in the presence of a boron trifluoride complex catalyst, of a furan compound with CHXY (X: H, Cl, Br; Y: Cl, Br) or with RCOOH in the presence of (XYCHCO)20.

  在三氟化硼络合物催化剂存在下，通过呋喃化合物与 CHXY（X：H、Cl、Br；Y：Cl、Br）或与 RCOOH 在 (XYCHCO)20 存在下发生反应，可高产制备 2-酰基呋喃衍生物（R：烷基、苯基等；R1：H、烷基）。
• Cover window plate and image display device including the same
  申请人：DONGWOO FINE-CHEM CO., LTD.

  公开号：US10391750B2

  公开（公告）日：2019-08-27

  A cover window plate includes an organic-inorganic hybrid hard coating layer on at least one surface of a polymer substrate film, wherein the plate has a pencil hardness of 4H or more under a load of 1 kg, such that an occurrence of deflection in the plate under severe conditions such as high temperature and high humidity atmospheres may be significantly reduced, thus to achieve excellent durability and optical characteristics when applying to products, as well as excellent anti-fingerprint properties of a surface, and an image display device including the cover window plate.

  一种盖视窗板，包括在聚合物基底薄膜至少一个表面上的有机-无机杂化硬涂层，其中该板在 1 千克负荷下的铅笔硬度为 4H 或更高，从而可显著降低板在高温和高湿环境等恶劣条件下发生变形的可能性，因此在应用于产品时可获得出色的耐用性和光学特性，以及出色的表面防指纹特性，以及包括该盖视窗板的图像显示设备。