ethyl N-methyl-N'-nitroimidocarbamate

• 分子结构分类: 有机化合物 - 有机1,3-偶极化合物 - 烯丙基型1,3-偶极有机化合物
• 英文名称: ethyl N-methyl-N'-nitroimidocarbamate
• 英文别名: O-ethyl-N-methyl-N'-nitroisourea；ethyl N-methyl-N'-nitrocarbamimidate
• 化学式: C₄H₉N₃O₃
• 分子量: 147.134
• InChiKey: GUXRUOISIJHUKH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  79.4
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  O-ethyl-N-nitroisourea 、 盐酸甲胺 在 sodium chloride 、 碳酸氢钠 作用下， 以 水 为溶剂， 反应 15.0h， 以70%的产率得到ethyl N-methyl-N'-nitroimidocarbamate
  参考文献：
  名称：

  EP1985610

  摘要：

  公开号：

文献信息

• Reaction of N-alkyl-N′-(trimethylsilyl)carbodiimides with nitrating agents. The synthesis of N-(tert-butyl)-N′-nitrocarbodiimide
  作者：A. M. Churakov、S. L. Ioffe、A. A. Voronin、V. A. Tartakovsky

  DOI：10.1007/s11172-018-2037-3

  日期：2018.1

  Reaction of N-Alk-N′-(trimethylsilyl)carbodiimides (Alk = Me, But) with nitrating agents (N2O5, (NO2)2SiF6) affords alkyl(nitro)cyanamides and N-alkyl-N′-nitrocarbodiimides. The product ratio depends on the reaction conditions. N-(tert-butyl)-N′-nitrocarbodiimide can be obtained in almost pure form. This compound is stable at temperatures below 10 °C. Its structure was confirmed by 1Н, 13C, and 14N

  N-Alk-N'-(三甲基甲硅烷基)碳二亚胺(Alk = Me, But)与硝化剂(N2O5, (NO2)2SiF6)反应得到烷基(硝基)氰胺和N-烷基-N'-硝基碳二亚胺。产物比例取决于反应条件。N-(叔丁基)-N'-硝基碳二亚胺可以几乎纯的形式获得。该化合物在低于 10 °C 的温度下是稳定的。其结构经 1Н、13C 和 14N NMR 确证。N-(叔丁基)-N'-硝基碳二亚胺与胺的反应为制备N-烷基(芳基)-取代的N'-(叔丁基)-N″-硝基胍提供了一条新途径。
• PROCESS FOR PRODUCING NITROISOUREA DERIVATIVES
  申请人：Kamekawa Hisato

  公开号：US20090018363A1

  公开（公告）日：2009-01-15

  Disclosed is an improved process for producing nitroisourea derivatives which is necessary for producing nitroguanidine derivatives having an insecticidal activity. Specifically disclosed is a process for producing nitroisourea derivatives represented by the following general formula (3), which is characterized in that nitroisourea derivatives represented by the following general formula (1) and amines represented by the following general formula (2) or a salt thereof are reacted in the presence of a catalytic amount of a hydrogen carbonate,

  本发明公开了一种改进的生产硝基异脲衍生物的方法，该方法是生产具有杀虫活性的硝基胍衍生物所必需的。具体公开了一种生产由以下通式（3）表示的硝基异脲衍生物的方法，其特征在于在氢碳酸盐的催化作用下，将由以下通式（1）表示的硝基异脲衍生物和由以下通式（2）表示的胺或其盐反应。
• Process for producing nitroisourea derivatives
  申请人：Mitsui Chemicals, Inc.

  公开号：US07560593B2

  公开（公告）日：2009-07-14

  Disclosed is an improved process for producing nitroisourea derivatives which is necessary for producing nitroguanidine derivatives having an insecticidal activity. Specifically disclosed is a process for producing nitroisourea derivatives represented by the following general formula (3), which is characterized in that nitroisourea derivatives represented by the following general formula (1) and amines represented by the following general formula (2) or a salt thereof are reacted in the presence of a catalytic amount of a hydrogen carbonate,

  公开了一种改进的生产硝基异脲衍生物的方法，这是生产具有杀虫活性的硝基胍衍生物所必需的。具体地，公开了一种生产由下列通式（3）表示的硝基异脲衍生物的方法，其特征在于在氢碳酸盐的催化作用下，将由下列通式（1）表示的硝基异脲衍生物和由下列通式（2）表示的胺或其盐反应。