bis(4-methoxy-3,5-dimethylphenyl)methanone | 110047-35-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: bis(4-methoxy-3,5-dimethylphenyl)methanone
• 英文别名: 4,4'-dimethoxy-3,3',5,5'-tetramethylbenzophenone；4,4’-dimethoxy-3,3’,5,5’-dimethylbenzophenone；4,4'-dimethoxy-3,5,3',5'-tetramethyl-benzophenone；4,4'-Dimethoxy-3,5,3',5'-tetramethyl-benzophenon
• CAS: 110047-35-3
• 化学式: C₁₉H₂₂O₃
• 分子量: 298.382
• InChiKey: CVENOQACGMUHOV-UHFFFAOYSA-N

物化性质

• 沸点：
  455.6±45.0 °C(Predicted)
• 密度：
  1.063±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  bis(4-methoxy-3,5-dimethylphenyl)methanone 在 1,3-二甲基-2-咪唑啉酮 、 正丁基锂 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 反应 188.0h， 生成 bis(4-methoxy-3,5-dimethylphenyl)(cyclopentadienyl)(octamethyloctahydrodibenzofluorenyl)methane
  参考文献：
  名称：

  Process for producing ethylene/α-olefin copolymer

  摘要：

  提供了一种能够在高聚合温度条件下产生具有高分子量的乙烯/α-烯烃共聚物的工艺。生产乙烯/α-烯烃共聚物的工艺包括在存在包括交联的茂金属化合物（A）和辅助催化剂组分（B）的烯烃聚合催化剂的情况下，共聚乙烯和具有3个或更多碳原子的α-烯烃。在通用公式[I]中，Y从碳原子等中选择，M是钽原子或类似物，R1至R12分别从氢原子、碳氢基团等中选择，R13和R14分别是取代芳基团或类似物，其中R13和R14中至少一个是具有一个或多个电子给予取代基的取代芳基团，其Hammett取代常数σ不超过-0.2，Q从卤素原子等中选择，j是1至4之间的整数。

  公开号：

  US09969827B2
• 作为产物：
  描述：

  2,6-二甲基苯酚 在 sodium hydroxide 、 双氧水 、 zinc(II) chloride 作用下， 生成 bis(4-methoxy-3,5-dimethylphenyl)methanone
  参考文献：
  名称：

  611.二甲苯酚与四卤化碳的缩合

  摘要：

  DOI：

  10.1039/jr9580003009

文献信息

• Sodium Methyl Carbonate as an Effective C1 Synthon. Synthesis of Carboxylic Acids, Benzophenones, and Unsymmetrical Ketones
  作者：Timothy E. Hurst、Julie A. Deichert、Lucas Kapeniak、Roland Lee、Jesse Harris、Philip G. Jessop、Victor Snieckus

  DOI：10.1021/acs.orglett.9b00773

  日期：2019.6.7

  Reported is the synthesis of carboxylic acids, symmetrical ketones, and unsymmetrical ketones with selectivity achieved by exploiting the differential reactivity of sodium methyl carbonate with Grignard and organolithium reagents.

  报道了通过利用碳酸镁钠与格利雅（Grignard）和有机锂试剂的差异反应性而实现的选择性合成羧酸，对称酮和不对称酮的方法。
• Iodine-catalyzed disproportionation of aryl-substituted ethers under solvent-free reaction conditions
  作者：Marjan Jereb、Dejan Vražič

  DOI：10.1039/c3ob27267b

  日期：——

  iodine produced triphenylmethane and the corresponding aldehydes and ketones. The electron-donating substituents facilitated the reaction, while the electron-withdrawing groups retarded it; the difference in reactivity is not very high. Such an observation may be in favour of hydride transfer, predominantly from the less electron rich side of the ether with more stable carbocation formation. With the isotopic

  碘被证明是在无溶剂反应条件下芳基取代的醚歧化的有效催化剂。将各种取代的1,1,1'，1'-四芳基二甲基醚转化为相应的二芳基酮和二芳基甲烷衍生物。由I 2催化的4-甲氧基苯基取代的醚的转化也产生了单烷基化和二烷基化的Friedel-Crafts产品。用催化量的碘处理三苯甲基烷基和三苯甲基苄基醚三苯甲烷以及相应的醛和酮。供电子的取代基促进了反应，而吸电子基团阻止了该反应。反应性差异不是很大。这种观察可能有利于氢化物转移，主要是从醚的电子富集较少的一侧开始，具有更稳定的碳正离子形成。通过同位素研究，可以确定，大部分的C–H键断裂在速率确定步骤中发生，而羰基氧原子则起源于起始醚，而不是空气。转化是在空气和氩气下进行的，HI不是起作用的催化剂。
• METHOD FOR PRODUCING ETHYLENE/ALPHA-OLEFIN COPOLYMER
  申请人：Mitsui Chemicals, Inc.

  公开号：EP3106475A1

  公开（公告）日：2016-12-21

  A process capable of producing an ethylene/α-olefin copolymer having a high molecular weight even under the conditions of a high polymerization temperature is provided. The process for producing an ethylene/α-olefin copolymer includes copolymerizing ethylene and an α-olefin having 3 or more carbon atoms in the presence of an olefin polymerization catalyst including a crosslinked metallocene compound (A) represented by the following general formula [I] and a cocatalyst component (B). In the general formula [I], Y is selected from a carbon atom, etc. , M is a hafnium atom or the like, R1 to R12 are each selected from a hydrogen atom, a hydrocarbon group, etc., R13 and R14 are each a substituted aryl group or the like, at least one of R13 and R14 is a substituted aryl group having one or more electron-donating substituents having a Hammett substituent constant σ of not more than -0.2, Q is selected from a halogen atom, etc., and j is an integer of 1 to 4.

  提供了一种即使在高聚合温度条件下也能生产高分子量乙烯/α-烯烃共聚物的工艺。生产乙烯/α-烯烃共聚物的工艺包括在烯烃聚合催化剂存在下，使乙烯和具有 3 个或 3 个以上碳原子的 α-烯烃共聚，烯烃聚合催化剂包括由以下通式[I]表示的交联茂金属化合物（A）和助催化剂组分（B）。在通式[I]中，Y 选自碳原子等。M是铪原子或类似物，R1至R12各自选自氢原子、烃基等，R13和R14各自是取代的芳基或类似物，R13和R14中至少有一个是具有一个或多个电子-捐赠取代基的取代芳基，其哈密特取代基常数σ不大于-0.2，Q选自卤素原子等，j是1至4的整数。
• Crystal structures and isometricity comparison of methylated bisphenol F derivatives
  作者：Tobias Gruber、Robert Nestler、Wilhelm Seichter、Petra Bombicz

  DOI：10.1016/j.molstruc.2013.10.060

  日期：2014.1

  The syntheses and X-ray structures of three methylated bisphenol F derivatives and one respective analogue are reported. A special emphasis lies on the influence of methyl groups on the conformation of the common diphenylmethane scaffold. The introduction of four methyl groups to bisphenol F was found not to disturb its typical strong hydrogen bond network, and yet, to change the pattern of the aromatic interactions in the overall packing. According to the isometricity comparison, the addition of methyl groups to the diphenylmethane core has a greater influence on the conformation of the individual molecules, than the presence or absence of hydrogen bonding donors or acceptors. (C) 2013 Elsevier B.V. All rights reserved.
• PROCESS FOR PRODUCING ETHYLENE/ALPHA-OLEFIN COPOLYMER
  申请人：MITSUI CHEMICALS, INC.

  公开号：US20170183432A1

  公开（公告）日：2017-06-29

  A process capable of producing an ethylene/α-olefin copolymer having a high molecular weight even under the conditions of a high polymerization temperature is provided. The process for producing an ethylene/α-olefin copolymer includes copolymerizing ethylene and an α-olefin having 3 or more carbon atoms in the presence of an olefin polymerization catalyst including a crosslinked metallocene compound (A) represented by the following general formula [I] and a cocatalyst component (B). In the general formula [I], Y is selected from a carbon atom, etc., M is a hafnium atom or the like, R 1 to R 12 are each selected from a hydrogen atom, a hydrocarbon group, etc., R 13 and R 14 are each a substituted aryl group or the like, at least one of R 13 and R 14 is a substituted aryl group having one or more electron-donating substituents having a Hammett substituent constant σ of not more than −0.2, Q is selected from a halogen atom, etc., and j is an integer of 1 to 4.