dithiodianiline | 106950-44-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: dithiodianiline
• 英文别名: Bis--disulfid；Bis-(diphenylimino)-disulfid；N-(anilinodisulfanyl)aniline
• CAS: 106950-44-1
• 化学式: C₁₂H₁₂N₂S₂
• 分子量: 248.373
• InChiKey: BIHJEIFLAWVSQP-UHFFFAOYSA-N

物化性质

• 沸点：
  384.7±25.0 °C(Predicted)
• 密度：
  1.348±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  74.7
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  dithiodianiline 在 吡啶 、 C₃₃H₅₁N₃OS 、 水 、 三苯基膦 作用下， 以 四氢呋喃 、 甲苯 为溶剂， 反应 96.0h， 生成 (E)-S-(2-(4-methylphenylsulfonamido)phenyl)-3-phenylprop-2-enethioate
  参考文献：
  名称：

  光学活性 1,5-苯并噻嗪类药物的简便净环加成方法

  摘要：

  1,5-苯并硫氮杂是众所周知的多功能药效团，其衍生物有望对抗多种疾病。因此，需要开发一种合成路线，能够简便地对映选择性制备范围广泛的此类衍生物。尽管环加成方法可以被认为是获得这些化合物的可能途径，但迄今为止，还没有此类方案的先例。因此，我们提出了第一个高对映选择性净 [4 + 3] 环加成的例子，通过利用由手性异硫脲催化剂产生的 α,β-不饱和酰基铵中间体来提供 1,5-苯并硫氮杂，该催化剂经历了 2-氨基苯硫酚的两次连续化学选择性亲核攻击. 该方案提供了具有极高区域选择性的环加合物，无论基材的空间和电子特性如何，都可以实现从良好到卓越的立体选择性。因此，该方法为构建用于测定评估的光学活性 1,5-苯并噻嗪类库提供了有前景的合成路线。

  DOI：

  10.1021/jacs.5b02537
• 作为产物：
  描述：

  二氯化二硫 、 苯胺 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 1.0h， 以65%的产率得到dithiodianiline
  参考文献：
  名称：

  Synthesis and antimicrobial activities of structurally novel S,S′-bis(heterosubstituted) disulfides

  摘要：

  The central focus of this study is on the antibacterial and antifungal properties of synthetically produced S,S'-bis(heterosubstituted) disulfides as a means to control the growth of various infection-causing pathogens. Staphylococcus aureus, Francisella tularensis and Candida albicans were each found to be highly susceptible to several of these compounds by agar or broth dilution and Kirby-Bauer diffusion assays. These structurally simple, low molecular weight disulfides have shown promising bioactivities and may serve as leads to the development of effective new antibacterials for pathogenic bacteria such as methicillinresistant S. aureus and F. tularensis. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2012.04.056

文献信息

• Method for producing trimer of indole derivative, and trimer of indole derivative and laminated structure thereof
  申请人：——

  公开号：US20040019097A1

  公开（公告）日：2004-01-29

  The present invention provides an industrial method that allows to produce an indole derivative trimer with high purity in mass, as well as novel indole derivative trimers obtainable by the method, having high conductivity, high oxidation—reduction potential, high oxidation—reduction capacity, and the excellent cycle characteristics. The present invention relates to a method of producing an indole derivative trimer comprising the step of oxidizing an indole derivative in a reaction solution containing an organic solvent and to the novel trimers produced by the method.

  本发明提供了一种工业方法，可以在反应溶液中氧化含有有机溶剂的吲哚衍生物，从而制备高纯度的吲哚衍生物三聚体，并获得具有高电导率、高氧化还原电位、高氧化还原容量和优异循环特性的新型吲哚衍生物三聚体。本发明涉及一种制备吲哚衍生物三聚体的方法，包括氧化含有有机溶剂的吲哚衍生物的步骤，以及通过该方法制备的新型三聚体。
• METHOD FOR PRODUCING TRIMER OF INDOLE DERIVATIVE, AND TRIMER OF INDOLE DERIVATIVE AND LAMINATED STRUCTURE THEREOF
  申请人：Mitsubishi Rayon Co., Ltd.

  公开号：EP1327632A1

  公开（公告）日：2003-07-16

  The present invention provides an industrial method that allows to produce an indole derivative trimer with high purity in mass, as well as novel indole derivative trimers obtainable by the method, having high conductivity, high oxidation - reduction potential, high oxidation - reduction capacity, and the excellent cycle characteristics. The present invention relates to a method of producing an indole derivative trimer comprising the step of oxidizing an indole derivative in a reaction solution containing an organic solvent and to the novel trimers produced by the method.

  本发明提供了一种工业方法，该方法可生产出高纯度的吲哚衍生物三聚体，以及可通过该方法获得的新型吲哚衍生物三聚体，该三聚体具有高导电性、高氧化-还原电位、高氧化-还原能力和优异的循环特性。本发明涉及一种生产吲哚衍生物三聚体的方法，该方法包括在含有有机溶剂的反应溶液中氧化吲哚衍生物的步骤，还涉及用该方法生产的新型三聚体。
• INORGANIC/ORGANIC COMPLEX NANO-BEADS AND METHOD FOR MANUFACTURING THE SAME
  申请人：Naoi, Katsuhiko

  公开号：EP1376619A1

  公开（公告）日：2004-01-02

  An inorganic/organic composite material which is advantageous in physical characteristics (mechanical strength), chemical characteristics (thermal stability) and electric characteristics (electric conductivity), as compared with a sole system, as being compounded in nano order. An improved energy storage device using the inorganic/organic composite nano-beads, and especially an improved electrochemical capacitor for covering the range of a power energy density which cannot be achieved with devices of the prior art. A method of producing the inorganic/- organic composite nano-beads. The inorganic/organic composite nano-beads have a three-dimensional structure in which nuclei are made of an inorganic material having a particle diameter of nano order and a high electronic conductivity, and are covered with thin films of an organic conductive material.

  一种无机/有机复合材料，与单一体系相比，纳米级复合材料在物理特性（机械强度）、化学特性（热稳定性）和电气特性（导电性）方面更具优势。一种使用无机/有机复合纳米珠的改进型储能装置，特别是一种改进型电化学电容器，可覆盖现有技术装置无法达到的功率能量密度范围。一种生产无机/有机复合纳米珠的方法。 无机/有机复合纳米珠具有三维结构，其中核由颗粒直径为纳米级且具有高电子导电性的无机材料制成，并覆盖有一层有机导电材料薄膜。
• Antibacterial S-heterosubstituted disulfides
  申请人：Turos Edward

  公开号：US10350177B2

  公开（公告）日：2019-07-16

  Synthetically-derived S,S-heterodisubstituted disulfides that exhibit potent in vitro antibacterial activity against a variety of bacteria, including Staphylococcus aureus, methicillin-resistant Staphylococcus aureus and Francisella tularensis. The present invention provides compounds, methods and compositions effective to treat microbial/bacterial infections, and, especially, infections arising from bacteria which have developed resistance to conventional antibiotics.

  合成衍生的 S,S-互二取代二硫化物对多种细菌（包括金黄色葡萄球菌、耐甲氧西林金黄色葡萄球菌和土拉弗氏菌）具有强效的体外抗菌活性。本发明提供了有效治疗微生物/细菌感染的化合物、方法和组合物，特别是治疗对传统抗生素产生抗药性的细菌引起的感染。
• Inorganic/organic complex nano-beads and method for manufacturing the same
  申请人：——

  公开号：US20040151907A1

  公开（公告）日：2004-08-05

  An inorganic/organic composite material which is advantageous in physical characteristics (mechanical strength), chemical characteristics (thermal stability) and electric characteristics (electric conductivity), as compared with a sole system, as being compounded in nano order. An improved energy storage device using the inorganic/organic composite nano-beads, and especially an improved electrochemical capacitor for covering the range of a power energy density which cannot be achieved with devices of the prior art. A method of producing the inorganic/organic composite nano-beads. The inorganic/organic composite nano-beads have a three-dimensional structure in which nuclei are made of an inorganic material having a particle diameter of nano order and a high electronic conductivity, and are covered with thin films of an organic conductive material.

  一种无机/有机复合材料，与单一体系相比，纳米级复合材料在物理特性（机械强度）、化学特性（热稳定性）和电气特性（导电性）方面更具优势。一种使用无机/有机复合纳米珠的改进型储能装置，特别是一种改进型电化学电容器，可覆盖现有技术装置无法达到的功率能量密度范围。一种生产无机/有机复合纳米珠的方法。无机/有机复合纳米珠具有三维结构，其中核由颗粒直径为纳米级且具有高电子导电性的无机材料制成，并覆盖有一层有机导电材料薄膜。